These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

302 related articles for article (PubMed ID: 16236767)

  • 1. Mice deficient in Ext2 lack heparan sulfate and develop exostoses.
    Stickens D; Zak BM; Rougier N; Esko JD; Werb Z
    Development; 2005 Nov; 132(22):5055-68. PubMed ID: 16236767
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Compound heterozygous loss of Ext1 and Ext2 is sufficient for formation of multiple exostoses in mouse ribs and long bones.
    Zak BM; Schuksz M; Koyama E; Mundy C; Wells DE; Yamaguchi Y; Pacifici M; Esko JD
    Bone; 2011 May; 48(5):979-87. PubMed ID: 21310272
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Heparan sulfate abnormalities in exostosis growth plates.
    Hecht JT; Hall CR; Snuggs M; Hayes E; Haynes R; Cole WG
    Bone; 2002 Jul; 31(1):199-204. PubMed ID: 12110435
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Transgenic expression of the EXT2 gene in developing chondrocytes enhances the synthesis of heparan sulfate and bone formation in mice.
    Morimoto K; Shimizu T; Furukawa K; Morio H; Kurosawa H; Shirasawa T
    Biochem Biophys Res Commun; 2002 Apr; 292(4):999-1009. PubMed ID: 11944914
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Epiphyseal abnormalities, trabecular bone loss and articular chondrocyte hypertrophy develop in the long bones of postnatal Ext1-deficient mice.
    Sgariglia F; Candela ME; Huegel J; Jacenko O; Koyama E; Yamaguchi Y; Pacifici M; Enomoto-Iwamoto M
    Bone; 2013 Nov; 57(1):220-31. PubMed ID: 23958822
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The pathogenic roles of heparan sulfate deficiency in hereditary multiple exostoses.
    Pacifici M
    Matrix Biol; 2018 Oct; 71-72():28-39. PubMed ID: 29277722
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Differentiation-induced loss of heparan sulfate in human exostosis derived chondrocytes.
    Hecht JT; Hayes E; Haynes R; Cole WG; Long RJ; Farach-Carson MC; Carson DD
    Differentiation; 2005 Jun; 73(5):212-21. PubMed ID: 16026543
    [TBL] [Abstract][Full Text] [Related]  

  • 8. EXT genes are differentially expressed in bone and cartilage during mouse embryogenesis.
    Stickens D; Brown D; Evans GA
    Dev Dyn; 2000 Jul; 218(3):452-64. PubMed ID: 10878610
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Loss of function in heparan sulfate elongation genes EXT1 and EXT 2 results in improved nitric oxide bioavailability and endothelial function.
    Mooij HL; Cabrales P; Bernelot Moens SJ; Xu D; Udayappan SD; Tsai AG; van der Sande MA; de Groot E; Intaglietta M; Kastelein JJ; Dallinga-Thie GM; Esko JD; Stroes ES; Nieuwdorp M
    J Am Heart Assoc; 2014 Dec; 3(6):e001274. PubMed ID: 25468659
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Disruption of gastrulation and heparan sulfate biosynthesis in EXT1-deficient mice.
    Lin X; Wei G; Shi Z; Dryer L; Esko JD; Wells DE; Matzuk MM
    Dev Biol; 2000 Aug; 224(2):299-311. PubMed ID: 10926768
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Heparan sulfate deficiency leads to hypertrophic chondrocytes by increasing bone morphogenetic protein signaling.
    Kawashima K; Ogawa H; Komura S; Ishihara T; Yamaguchi Y; Akiyama H; Matsumoto K
    Osteoarthritis Cartilage; 2020 Nov; 28(11):1459-1470. PubMed ID: 32818603
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Unsuspected osteochondroma-like outgrowths in the cranial base of Hereditary Multiple Exostoses patients and modeling and treatment with a BMP antagonist in mice.
    Sinha S; Mundy C; Bechtold T; Sgariglia F; Ibrahim MM; Billings PC; Carroll K; Koyama E; Jones KB; Pacifici M
    PLoS Genet; 2017 Apr; 13(4):e1006742. PubMed ID: 28445472
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Association of EXT1 and EXT2, hereditary multiple exostoses gene products, in Golgi apparatus.
    Kobayashi S; Morimoto K; Shimizu T; Takahashi M; Kurosawa H; Shirasawa T
    Biochem Biophys Res Commun; 2000 Feb; 268(3):860-7. PubMed ID: 10679296
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Contribution of EXT1, EXT2, and EXTL3 to heparan sulfate chain elongation.
    Busse M; Feta A; Presto J; Wilén M; Grønning M; Kjellén L; Kusche-Gullberg M
    J Biol Chem; 2007 Nov; 282(45):32802-10. PubMed ID: 17761672
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Haploinsufficiency of EXT1 and Heparan Sulphate Deficiency Associated with Hereditary Multiple Exostoses in a Pakistani Family.
    Ajmal M; Muhammad H; Nasir M; Shoaib M; Malik SA; Ullah I
    Medicina (Kaunas); 2022 Dec; 59(1):. PubMed ID: 36676722
    [No Abstract]   [Full Text] [Related]  

  • 16. The putative tumour suppressor EXT1 alters the expression of cell-surface heparan sulfate.
    McCormick C; Leduc Y; Martindale D; Mattison K; Esford LE; Dyer AP; Tufaro F
    Nat Genet; 1998 Jun; 19(2):158-61. PubMed ID: 9620772
    [TBL] [Abstract][Full Text] [Related]  

  • 17. A mouse model of chondrocyte-specific somatic mutation reveals a role for Ext1 loss of heterozygosity in multiple hereditary exostoses.
    Matsumoto K; Irie F; Mackem S; Yamaguchi Y
    Proc Natl Acad Sci U S A; 2010 Jun; 107(24):10932-7. PubMed ID: 20534475
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Heparan sulfate in skeletal development, growth, and pathology: the case of hereditary multiple exostoses.
    Huegel J; Sgariglia F; Enomoto-Iwamoto M; Koyama E; Dormans JP; Pacifici M
    Dev Dyn; 2013 Sep; 242(9):1021-32. PubMed ID: 23821404
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Hereditary multiple exostoses and heparan sulfate polymerization.
    Zak BM; Crawford BE; Esko JD
    Biochim Biophys Acta; 2002 Dec; 1573(3):346-55. PubMed ID: 12417417
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Signaling systems affecting the severity of multiple osteochondromas.
    Piombo V; Jochmann K; Hoffmann D; Wuelling M; Vortkamp A
    Bone; 2018 Jun; 111():71-81. PubMed ID: 29545125
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 16.