218 related articles for article (PubMed ID: 16244363)
1. Long QT syndrome-associated I593R mutation in HERG potassium channel activates ER stress pathways.
Keller SH; Platoshyn O; Yuan JX
Cell Biochem Biophys; 2005; 43(3):365-77. PubMed ID: 16244363
[TBL] [Abstract][Full Text] [Related]
2. Trafficking-deficient G572R-hERG and E637K-hERG activate stress and clearance pathways in endoplasmic reticulum.
Wang Y; Huang X; Zhou J; Yang X; Li D; Mao H; Sun HH; Liu N; Lian J
PLoS One; 2012; 7(1):e29885. PubMed ID: 22242185
[TBL] [Abstract][Full Text] [Related]
3. Mechanisms of pharmacological rescue of trafficking-defective hERG mutant channels in human long QT syndrome.
Gong Q; Jones MA; Zhou Z
J Biol Chem; 2006 Feb; 281(7):4069-74. PubMed ID: 16361248
[TBL] [Abstract][Full Text] [Related]
4. HERG-F463L potassium channels linked to long QT syndrome reduce I(Kr) current by a trafficking-deficient mechanism.
Yang HT; Sun CF; Cui CC; Xue XL; Zhang AF; Li HB; Wang DQ; Shu J
Clin Exp Pharmacol Physiol; 2009 Aug; 36(8):822-7. PubMed ID: 19215240
[TBL] [Abstract][Full Text] [Related]
5. Inhibitory effects and mechanism of dihydroberberine on hERG channels expressed in HEK293 cells.
Yu D; Lv L; Fang L; Zhang B; Wang J; Zhan G; Zhao L; Zhao X; Li B
PLoS One; 2017; 12(8):e0181823. PubMed ID: 28763460
[TBL] [Abstract][Full Text] [Related]
6. Trafficking-deficient hERG K⁺ channels linked to long QT syndrome are regulated by a microtubule-dependent quality control compartment in the ER.
Smith JL; McBride CM; Nataraj PS; Bartos DC; January CT; Delisle BP
Am J Physiol Cell Physiol; 2011 Jul; 301(1):C75-85. PubMed ID: 21490315
[TBL] [Abstract][Full Text] [Related]
7. Pharmacological correction of long QT-linked mutations in KCNH2 (hERG) increases the trafficking of Kv11.1 channels stored in the transitional endoplasmic reticulum.
Smith JL; Reloj AR; Nataraj PS; Bartos DC; Schroder EA; Moss AJ; Ohno S; Horie M; Anderson CL; January CT; Delisle BP
Am J Physiol Cell Physiol; 2013 Nov; 305(9):C919-30. PubMed ID: 23864605
[TBL] [Abstract][Full Text] [Related]
8. hERG quality control and the long QT syndrome.
Foo B; Williamson B; Young JC; Lukacs G; Shrier A
J Physiol; 2016 May; 594(9):2469-81. PubMed ID: 26718903
[TBL] [Abstract][Full Text] [Related]
9. [Progress in research on defective protein trafficking and functional restoration in HERG-associated long QT syndrome].
Fang P; Lian J
Zhonghua Yi Xue Yi Chuan Xue Za Zhi; 2016 Feb; 33(1):101-4. PubMed ID: 26829745
[TBL] [Abstract][Full Text] [Related]
10. Re-trafficking of hERG reverses long QT syndrome 2 phenotype in human iPS-derived cardiomyocytes.
Mehta A; Sequiera GL; Ramachandra CJ; Sudibyo Y; Chung Y; Sheng J; Wong KY; Tan TH; Wong P; Liew R; Shim W
Cardiovasc Res; 2014 Jun; 102(3):497-506. PubMed ID: 24623279
[TBL] [Abstract][Full Text] [Related]
11. Mouse ERG K(+) channel clones reveal differences in protein trafficking and function.
Lin EC; Moungey BM; Lim E; Concannon SP; Anderson CL; Kyle JW; Makielski JC; Balijepalli SY; January CT
J Am Heart Assoc; 2014 Dec; 3(6):e001491. PubMed ID: 25497881
[TBL] [Abstract][Full Text] [Related]
12. Human ether-a-go-go related gene (hERG) K+ channels: function and dysfunction.
Perrin MJ; Subbiah RN; Vandenberg JI; Hill AP
Prog Biophys Mol Biol; 2008; 98(2-3):137-48. PubMed ID: 19027781
[TBL] [Abstract][Full Text] [Related]
13. Hsp90 prevents interaction between CHIP and HERG proteins to facilitate maturation of wild-type and mutant HERG proteins.
Iwai C; Li P; Kurata Y; Hoshikawa Y; Morikawa K; Maharani N; Higaki K; Sasano T; Notsu T; Ishido Y; Miake J; Yamamoto Y; Shirayoshi Y; Ninomiya H; Nakai A; Murata S; Yoshida A; Yamamoto K; Hiraoka M; Hisatome I
Cardiovasc Res; 2013 Dec; 100(3):520-8. PubMed ID: 23963841
[TBL] [Abstract][Full Text] [Related]
14. Retention in the endoplasmic reticulum as a mechanism of dominant-negative current suppression in human long QT syndrome.
Ficker E; Dennis AT; Obejero-Paz CA; Castaldo P; Taglialatela M; Brown AM
J Mol Cell Cardiol; 2000 Dec; 32(12):2327-37. PubMed ID: 11113008
[TBL] [Abstract][Full Text] [Related]
15. Identification and functional characterization of the novel human ether-a-go-go-related gene (hERG) R744P mutant associated with hereditary long QT syndrome 2.
Aidery P; Kisselbach J; Gaspar H; Baldea I; Schweizer PA; Becker R; Katus HA; Thomas D
Biochem Biophys Res Commun; 2012 Feb; 418(4):830-5. PubMed ID: 22314138
[TBL] [Abstract][Full Text] [Related]
16. C-terminal HERG (LQT2) mutations disrupt IKr channel regulation through 14-3-3epsilon.
Choe CU; Schulze-Bahr E; Neu A; Xu J; Zhu ZI; Sauter K; Bähring R; Priori S; Guicheney P; Mönnig G; Neapolitano C; Heidemann J; Clancy CE; Pongs O; Isbrandt D
Hum Mol Genet; 2006 Oct; 15(19):2888-902. PubMed ID: 16923798
[TBL] [Abstract][Full Text] [Related]
17. HERG mutation predicts short QT based on channel kinetics but causes long QT by heterotetrameric trafficking deficiency.
Paulussen AD; Raes A; Jongbloed RJ; Gilissen RA; Wilde AA; Snyders DJ; Smeets HJ; Aerssens J
Cardiovasc Res; 2005 Aug; 67(3):467-75. PubMed ID: 15958262
[TBL] [Abstract][Full Text] [Related]
18. A splice site mutation in hERG leads to cryptic splicing in human long QT syndrome.
Gong Q; Zhang L; Moss AJ; Vincent GM; Ackerman MJ; Robinson JC; Jones MA; Tester DJ; Zhou Z
J Mol Cell Cardiol; 2008 Mar; 44(3):502-9. PubMed ID: 18272172
[TBL] [Abstract][Full Text] [Related]
19. Intracellular Mechanism of Rosuvastatin-Induced Decrease in Mature hERG Protein Expression on Membrane.
Feng PF; Zhang B; Zhao L; Fang Q; Liu Y; Wang JN; Xu XQ; Xue H; Li Y; Yan CC; Zhao X; Li BX
Mol Pharm; 2019 Apr; 16(4):1477-1488. PubMed ID: 30807184
[TBL] [Abstract][Full Text] [Related]
20. Identification and functional characterization of the human ether-a-go-go-related gene Q738X mutant associated with hereditary long QT syndrome type 2.
Han SN; Yang SH; Zhang Y; Sun XY; Duan YY; Hu XJ; Fan TL; Huang CZ; Yang G; Zhang Z; Zhang L
Int J Mol Med; 2014 Sep; 34(3):810-5. PubMed ID: 24993425
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]