198 related articles for article (PubMed ID: 16246051)
1. The role of cell-derived oligomers of Abeta in Alzheimer's disease and avenues for therapeutic intervention.
Walsh DM; Klyubin I; Shankar GM; Townsend M; Fadeeva JV; Betts V; Podlisny MB; Cleary JP; Ashe KH; Rowan MJ; Selkoe DJ
Biochem Soc Trans; 2005 Nov; 33(Pt 5):1087-90. PubMed ID: 16246051
[TBL] [Abstract][Full Text] [Related]
2. Synaptic plasticity disruption by amyloid beta protein: modulation by potential Alzheimer's disease modifying therapies.
Rowan MJ; Klyubin I; Wang Q; Anwyl R
Biochem Soc Trans; 2005 Aug; 33(Pt 4):563-7. PubMed ID: 16042545
[TBL] [Abstract][Full Text] [Related]
3. Amyloid beta protein immunotherapy neutralizes Abeta oligomers that disrupt synaptic plasticity in vivo.
Klyubin I; Walsh DM; Lemere CA; Cullen WK; Shankar GM; Betts V; Spooner ET; Jiang L; Anwyl R; Selkoe DJ; Rowan MJ
Nat Med; 2005 May; 11(5):556-61. PubMed ID: 15834427
[TBL] [Abstract][Full Text] [Related]
4. Orally available compound prevents deficits in memory caused by the Alzheimer amyloid-beta oligomers.
Townsend M; Cleary JP; Mehta T; Hofmeister J; Lesne S; O'Hare E; Walsh DM; Selkoe DJ
Ann Neurol; 2006 Dec; 60(6):668-76. PubMed ID: 17192927
[TBL] [Abstract][Full Text] [Related]
5. Synaptic memory mechanisms: Alzheimer's disease amyloid beta-peptide-induced dysfunction.
Rowan MJ; Klyubin I; Wang Q; Hu NW; Anwyl R
Biochem Soc Trans; 2007 Nov; 35(Pt 5):1219-23. PubMed ID: 17956317
[TBL] [Abstract][Full Text] [Related]
6. Synaptic plasticity in animal models of early Alzheimer's disease.
Rowan MJ; Klyubin I; Cullen WK; Anwyl R
Philos Trans R Soc Lond B Biol Sci; 2003 Apr; 358(1432):821-8. PubMed ID: 12740129
[TBL] [Abstract][Full Text] [Related]
7. LPYFDa neutralizes amyloid-beta-induced memory impairment and toxicity.
Granic I; Masman MF; Kees Mulder C; Nijholt IM; Naude PJ; de Haan A; Borbély E; Penke B; Luiten PG; Eisel UL
J Alzheimers Dis; 2010; 19(3):991-1005. PubMed ID: 20157254
[TBL] [Abstract][Full Text] [Related]
8. Mechanisms of the inhibitory effects of amyloid beta-protein on synaptic plasticity.
Rowan MJ; Klyubin I; Wang Q; Anwyl R
Exp Gerontol; 2004; 39(11-12):1661-7. PubMed ID: 15582282
[TBL] [Abstract][Full Text] [Related]
9. Soluble amyloid-beta peptides potently disrupt hippocampal synaptic plasticity in the absence of cerebrovascular dysfunction in vivo.
Hu NW; Smith IM; Walsh DM; Rowan MJ
Brain; 2008 Sep; 131(Pt 9):2414-24. PubMed ID: 18678563
[TBL] [Abstract][Full Text] [Related]
10. PP1 inhibition by Abeta peptide as a potential pathological mechanism in Alzheimer's disease.
Vintém AP; Henriques AG; da Cruz E Silva OA; da Cruz E Silva EF
Neurotoxicol Teratol; 2009; 31(2):85-8. PubMed ID: 19028567
[TBL] [Abstract][Full Text] [Related]
11. Engineered antibody intervention strategies for Alzheimer's disease and related dementias by targeting amyloid and toxic oligomers.
Robert R; Dolezal O; Waddington L; Hattarki MK; Cappai R; Masters CL; Hudson PJ; Wark KL
Protein Eng Des Sel; 2009 Mar; 22(3):199-208. PubMed ID: 18927231
[TBL] [Abstract][Full Text] [Related]
12. Analysis of Abeta interactions using ProteinChip technology.
Giannakis E; Hung LW; Camacaro KP; Smith DP; Barnham KJ; Wade JD
Methods Mol Biol; 2008; 494():71-86. PubMed ID: 18726569
[TBL] [Abstract][Full Text] [Related]
13. Formation of highly toxic soluble amyloid beta oligomers by the molecular chaperone prefoldin.
Sakono M; Zako T; Ueda H; Yohda M; Maeda M
FEBS J; 2008 Dec; 275(23):5982-93. PubMed ID: 19021772
[TBL] [Abstract][Full Text] [Related]
14. Beta-amyloid pathology in the entorhinal cortex of rats induces memory deficits: implications for Alzheimer's disease.
Sipos E; Kurunczi A; Kasza A; Horváth J; Felszeghy K; Laroche S; Toldi J; Párducz A; Penke B; Penke Z
Neuroscience; 2007 Jun; 147(1):28-36. PubMed ID: 17499931
[TBL] [Abstract][Full Text] [Related]
15. Direct in vivo intracellular selection of conformation-sensitive antibody domains targeting Alzheimer's amyloid-beta oligomers.
Meli G; Visintin M; Cannistraci I; Cattaneo A
J Mol Biol; 2009 Apr; 387(3):584-606. PubMed ID: 19361429
[TBL] [Abstract][Full Text] [Related]
16. RS-0406 arrests amyloid-beta oligomer-induced behavioural deterioration in vivo.
O'Hare E; Scopes DI; Treherne JM; Norwood K; Spanswick D; Kim EM
Behav Brain Res; 2010 Jun; 210(1):32-7. PubMed ID: 20138088
[TBL] [Abstract][Full Text] [Related]
17. Begacestat (GSI-953): a novel, selective thiophene sulfonamide inhibitor of amyloid precursor protein gamma-secretase for the treatment of Alzheimer's disease.
Martone RL; Zhou H; Atchison K; Comery T; Xu JZ; Huang X; Gong X; Jin M; Kreft A; Harrison B; Mayer SC; Aschmies S; Gonzales C; Zaleska MM; Riddell DR; Wagner E; Lu P; Sun SC; Sonnenberg-Reines J; Oganesian A; Adkins K; Leach MW; Clarke DW; Huryn D; Abou-Gharbia M; Magolda R; Bard J; Frick G; Raje S; Forlow SB; Balliet C; Burczynski ME; Reinhart PH; Wan HI; Pangalos MN; Jacobsen JS
J Pharmacol Exp Ther; 2009 Nov; 331(2):598-608. PubMed ID: 19671883
[TBL] [Abstract][Full Text] [Related]
18. Insulin rescues amyloid beta-induced impairment of hippocampal long-term potentiation.
Lee CC; Kuo YM; Huang CC; Hsu KS
Neurobiol Aging; 2009 Mar; 30(3):377-87. PubMed ID: 17692997
[TBL] [Abstract][Full Text] [Related]
19. The essential role of lipids in Alzheimer's disease.
Florent-Béchard S; Desbène C; Garcia P; Allouche A; Youssef I; Escanyé MC; Koziel V; Hanse M; Malaplate-Armand C; Stenger C; Kriem B; Yen-Potin FT; Olivier JL; Pillot T; Oster T
Biochimie; 2009 Jun; 91(6):804-9. PubMed ID: 19303044
[TBL] [Abstract][Full Text] [Related]
20. Virus and virus-like particle-based immunogens for Alzheimer's disease induce antibody responses against amyloid-beta without concomitant T cell responses.
Chackerian B; Rangel M; Hunter Z; Peabody DS
Vaccine; 2006 Sep; 24(37-39):6321-31. PubMed ID: 16806604
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]