These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

136 related articles for article (PubMed ID: 16248033)

  • 1. Nm 283, an efficient prodrug of the potent anti-HCV agent 2'-C-methylcytidine.
    Pierra C; Benzaria S; Amador A; Moussa A; Mathieu S; Storer R; Gosselin G
    Nucleosides Nucleotides Nucleic Acids; 2005; 24(5-7):767-70. PubMed ID: 16248033
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis and pharmacokinetics of valopicitabine (NM283), an efficient prodrug of the potent anti-HCV agent 2'-C-methylcytidine.
    Pierra C; Amador A; Benzaria S; Cretton-Scott E; D'Amours M; Mao J; Mathieu S; Moussa A; Bridges EG; Standring DN; Sommadossi JP; Storer R; Gosselin G
    J Med Chem; 2006 Nov; 49(22):6614-20. PubMed ID: 17064080
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Synthesis and characterization of 1'-C-cyano-2'-fluoro-2'-C-methyl pyrimidine nucleosides as HCV polymerase inhibitors.
    Kirschberg TA; Mish MR; Zhang L; Squires NH; Wang KY; Cho A; Feng JY; Fenaux M; Babusis D; Park Y; Ray AS; Kim CU
    Bioorg Med Chem Lett; 2015 Mar; 25(5):1040-3. PubMed ID: 25650256
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Monoval-LdC: efficient prodrug of 2'-deoxy-beta-L-cytidine (L-dC), a potent and selective anti-HBV agent.
    Benzaria S; Pierra C; Bardiot D; Cretton-Scott E; Bridges EG; Zhou XJ; Standring D; Gosselin G
    Nucleosides Nucleotides Nucleic Acids; 2003; 22(5-8):1003-6. PubMed ID: 14565331
    [TBL] [Abstract][Full Text] [Related]  

  • 5. 6-Hydrazinopurine 2'-methyl ribonucleosides and their 5'-monophosphate prodrugs as potent hepatitis C virus inhibitors.
    Gunic E; Chow S; Rong F; Ramasamy K; Raney A; Li DY; Huang J; Hamatake RK; Hong Z; Girardet JL
    Bioorg Med Chem Lett; 2007 May; 17(9):2456-8. PubMed ID: 17331718
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Cyclic monophosphate prodrugs of base-modified 2'-C-methyl ribonucleosides as potent inhibitors of hepatitis C virus RNA replication.
    Gunic E; Girardet JL; Ramasamy K; Stoisavljevic-Petkov V; Chow S; Yeh LT; Hamatake RK; Raney A; Hong Z
    Bioorg Med Chem Lett; 2007 May; 17(9):2452-5. PubMed ID: 17331721
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Antiviral efficacy upon administration of a HepDirect prodrug of 2'-C-methylcytidine to hepatitis C virus-infected chimpanzees.
    Carroll SS; Koeplinger K; Vavrek M; Zhang NR; Handt L; MacCoss M; Olsen DB; Reddy KR; Sun Z; van Poelje PD; Fujitaki JM; Boyer SH; Linemeyer DL; Hecker SJ; Erion MD
    Antimicrob Agents Chemother; 2011 Aug; 55(8):3854-60. PubMed ID: 21628542
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis of 3'-C-hydroxymethyl-substituted pyrimidine and purine nucleosides as potential anti-hepatitis C virus (HCV) agents.
    Pei X; Choi WJ; Kim YM; Zhao LX; Jeong LS
    Arch Pharm Res; 2008 Jul; 31(7):843-9. PubMed ID: 18704325
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis of 2-C-hydroxymethylribofuranosylpurines as potent anti-hepatitis C virus (HCV) agents.
    Yoo BN; Kim HO; Moon HR; Seol SK; Jang SK; Lee KM; Jeong LS
    Bioorg Med Chem Lett; 2006 Aug; 16(16):4190-4. PubMed ID: 16781148
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The application of phosphoramidate ProTide technology to the potent anti-HCV compound 4'-azidocytidine (R1479).
    McGuigan C; Kelleher MR; Perrone P; Mulready S; Luoni G; Daverio F; Rajyaguru S; Le Pogam S; Najera I; Martin JA; Klumpp K; Smith DB
    Bioorg Med Chem Lett; 2009 Aug; 19(15):4250-4. PubMed ID: 19505826
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Design, synthesis, and evaluation of liver-specific gemcitabine prodrugs for potential treatment of hepatitis C virus infection and hepatocellular carcinoma.
    Stephenson AA; Cao S; Taggart DJ; Vyavahare VP; Suo Z
    Eur J Med Chem; 2021 Mar; 213():113135. PubMed ID: 33454548
    [TBL] [Abstract][Full Text] [Related]  

  • 12. [Bicyclic furano[2,3-D] derivatives of pyrimidine nucleosides--synthesis and antiviral properties].
    Ivanov MA; Aleksandrova LA
    Bioorg Khim; 2013; 39(1):26-45. PubMed ID: 23844505
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Bifunctional aryloxyphosphoramidate prodrugs of 2'-C-Me-uridine: synthesis and anti-HCV activity.
    Maiti M; Gao LJ; Huang C; Ptak RG; Murray MG; De Jonghe S; Herdewijn P
    Org Biomol Chem; 2016 Sep; 14(37):8743-8757. PubMed ID: 27714209
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis and evaluation of 5'-modified 2'-deoxyadenosine analogues as anti-hepatitis C virus agents.
    Ikejiri M; Ohshima T; Fukushima A; Shimotohno K; Maruyama T
    Bioorg Med Chem Lett; 2008 Aug; 18(16):4638-41. PubMed ID: 18644724
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Design, synthesis, and antiviral activity of 2'-deoxy-2'-fluoro-2'-C-methylcytidine, a potent inhibitor of hepatitis C virus replication.
    Clark JL; Hollecker L; Mason JC; Stuyver LJ; Tharnish PM; Lostia S; McBrayer TR; Schinazi RF; Watanabe KA; Otto MJ; Furman PA; Stec WJ; Patterson SE; Pankiewicz KW
    J Med Chem; 2005 Aug; 48(17):5504-8. PubMed ID: 16107149
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis and biological evaluation of (3'S)-3'-deoxy-3'-fluoro-3'-C-ethynylcytidine.
    Clark JL; Clark CB; Mason JC
    Nucleosides Nucleotides Nucleic Acids; 2012 Apr; 31(4):286-92. PubMed ID: 22444191
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis and in vitro anti-HCV activity of beta-D- and 1-2'-deoxy-2'-fluororibonucleosides.
    Shi J; Du J; Ma T; Pankiewicz KW; Patterson SE; Hassan AE; Tharnish PM; McBrayer TR; Lostia S; Stuyver LJ; Watanabe KA; Chu CK; Schinazi RF; Otto MJ
    Nucleosides Nucleotides Nucleic Acids; 2005; 24(5-7):875-9. PubMed ID: 16248053
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Cyclic phosphoramidates as prodrugs of 2'-C-methylcytidine.
    Meppen M; Pacini B; Bazzo R; Koch U; Leone JF; Koeplinger KA; Rowley M; Altamura S; Di Marco A; Fiore F; Giuliano C; Gonzalez-Paz O; Laufer R; Pucci V; Narjes F; Gardelli C
    Eur J Med Chem; 2009 Sep; 44(9):3765-70. PubMed ID: 19493593
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synthesis and anti-hepatitis C virus (HCV) activity of 3'-C-substituted-methyl pyrimidine and purine nucleosides.
    Choi WJ; Kim YM; Kim HO; Lee HW; Kim DE; Park KS; Chong Y; Jeong LS
    Bioorg Med Chem; 2010 Jul; 18(13):4812-20. PubMed ID: 20627592
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The phosphoramidate ProTide approach greatly enhances the activity of beta-2'-C-methylguanosine against hepatitis C virus.
    McGuigan C; Perrone P; Madela K; Neyts J
    Bioorg Med Chem Lett; 2009 Aug; 19(15):4316-20. PubMed ID: 19523820
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.