442 related articles for article (PubMed ID: 16248670)
21. Structures, dynamics, and stabilities of fully modified locked nucleic acid (β-D-LNA and α-L-LNA) duplexes in comparison to pure DNA and RNA duplexes.
Suresh G; Priyakumar UD
J Phys Chem B; 2013 May; 117(18):5556-64. PubMed ID: 23617391
[TBL] [Abstract][Full Text] [Related]
22. Nuclease resistant methylphosphonate-DNA/LNA chimeric oligonucleotides.
Nagahama K; Veedu RN; Wengel J
Bioorg Med Chem Lett; 2009 May; 19(10):2707-9. PubMed ID: 19375912
[TBL] [Abstract][Full Text] [Related]
23. Free-radical ring closure to conformationally locked α-L-carba-LNAs and synthesis of their oligos: nuclease stability, target RNA specificity, and elicitation of RNase H.
Li Q; Yuan F; Zhou C; Plashkevych O; Chattopadhyaya J
J Org Chem; 2010 Sep; 75(18):6122-40. PubMed ID: 20738147
[TBL] [Abstract][Full Text] [Related]
24. Solution structures of DNA.RNA hybrids with purine-rich and pyrimidine-rich strands: comparison with the homologous DNA and RNA duplexes.
Gyi JI; Lane AN; Conn GL; Brown T
Biochemistry; 1998 Jan; 37(1):73-80. PubMed ID: 9425027
[TBL] [Abstract][Full Text] [Related]
25. Structural characterization of LNA and alpha-L-LNA hybridized to RNA.
Petersen M; Nielsen JT; Bondensgaard K; Wengel J; Jacobsen JP
Nucleosides Nucleotides Nucleic Acids; 2003; 22(5-8):1691-3. PubMed ID: 14565497
[TBL] [Abstract][Full Text] [Related]
26. Determination of affinity constants of locked nucleic acid (LNA) and DNA duplex formation using label free sensor technology.
Möhrle BP; Kumpf M; Gauglitz G
Analyst; 2005 Dec; 130(12):1634-8. PubMed ID: 16284662
[TBL] [Abstract][Full Text] [Related]
27. Thermodynamic, counterion and hydration effects for the incorporation of locked nucleic acid (LNA) nucleotides in duplex.
Kaur H; Arora A; Wengel J; Maiti S
Nucleic Acids Symp Ser (Oxf); 2008; (52):425-6. PubMed ID: 18776435
[TBL] [Abstract][Full Text] [Related]
28. Effect of LNA modifications on small molecule binding to nucleic acids.
Marin V; Hansen HF; Koch T; Armitage BA
J Biomol Struct Dyn; 2004 Jun; 21(6):841-50. PubMed ID: 15107006
[TBL] [Abstract][Full Text] [Related]
29. LNA (locked nucleic acid) and the diastereoisomeric alpha-L-LNA: conformational tuning and high-affinity recognition of DNA/RNA targets.
Wengel J; Petersen M; Nielsen KE; Jensen GA; Håkansson AE; Kumar R; Sørensen MD; Rajwanshi VK; Bryld T; Jacobsen JP
Nucleosides Nucleotides Nucleic Acids; 2001; 20(4-7):389-96. PubMed ID: 11563053
[TBL] [Abstract][Full Text] [Related]
30. Fine tuning of electrostatics around the internucleotidic phosphate through incorporation of modified 2',4'-carbocyclic-LNAs and -ENAs leads to significant modulation of antisense properties.
Zhou C; Liu Y; Andaloussi M; Badgujar N; Plashkevych O; Chattopadhyaya J
J Org Chem; 2009 Jan; 74(1):118-34. PubMed ID: 19055352
[TBL] [Abstract][Full Text] [Related]
31. Structural effect of complete [Rp]-phosphorothioate and phosphorodithioate substitutions in the DNA strand of a model antisense inhibitor-target RNA complex.
Furrer P; Billeci TM; Donati A; Kojima C; Karwowski B; Sierzchala A; Stec W; James TL
J Mol Biol; 1999 Jan; 285(4):1609-22. PubMed ID: 9917400
[TBL] [Abstract][Full Text] [Related]
32. Parallel RNA-strand recognition by 2'-amino-beta-L-LNA.
Kumar TS; Ostergaard ME; Sharma PK; Nielsen P; Wengel J; Hrdlicka PJ
Bioorg Med Chem Lett; 2009 May; 19(9):2396-9. PubMed ID: 19356930
[TBL] [Abstract][Full Text] [Related]
33. Energetic aspects of locked nucleic acids quadruplex association and dissociation.
Petraccone L; Erra E; Randazzo A; Giancola C
Biopolymers; 2006 Dec; 83(6):584-94. PubMed ID: 16944520
[TBL] [Abstract][Full Text] [Related]
34. Relationship of DNA structure to internal dynamics: correlation of helical parameters from NOE-based NMR solution structures of d(GCGTACGC)(2) and d(CGCTAGCG)(2) with (13)C order parameters implies conformational coupling in dinucleotide units.
Isaacs RJ; Spielmann HP
J Mol Biol; 2001 Mar; 307(2):525-40. PubMed ID: 11254380
[TBL] [Abstract][Full Text] [Related]
35. Locked nucleic acids and intercalating nucleic acids in the design of easily denaturing nucleic acids: thermal stability studies.
Filichev VV; Christensen UB; Pedersen EB; Babu BR; Wengel J
Chembiochem; 2004 Dec; 5(12):1673-9. PubMed ID: 15532065
[TBL] [Abstract][Full Text] [Related]
36. Interplay of LNA and 2'-O-methyl RNA in the structure and thermodynamics of RNA hybrid systems: a molecular dynamics study using the revised AMBER force field and comparison with experimental results.
Yildirim I; Kierzek E; Kierzek R; Schatz GC
J Phys Chem B; 2014 Dec; 118(49):14177-87. PubMed ID: 25268896
[TBL] [Abstract][Full Text] [Related]
37. Solution structures of 5-fluorouracil-substituted DNA and RNA decamer duplexes.
Sahasrabudhe PV; Pon RT; Gmeiner WH
Biochemistry; 1996 Oct; 35(42):13597-608. PubMed ID: 8885839
[TBL] [Abstract][Full Text] [Related]
38. Properties of nicked and circular dumbbell RNA-DNA chimeric oligonucleotides.
Yamakawa H; Hosono K; Ishibashi T; Takai K; Takaku H
Nucleic Acids Symp Ser; 1995; (34):133-4. PubMed ID: 8841588
[TBL] [Abstract][Full Text] [Related]
39. NMR and UV studies of 3'-S-phosphorothiolate modified DNA in a DNA : RNA hybrid dodecamer duplex; implications for antisense drug design.
Beevers AP; Fettes KJ; Sabbagh G; Murad FK; Arnold JR; Cosstick R; Fisher J
Org Biomol Chem; 2004 Jan; 2(1):114-9. PubMed ID: 14737669
[TBL] [Abstract][Full Text] [Related]
40. Conformational influence of the ribose 2'-hydroxyl group: crystal structures of DNA-RNA chimeric duplexes.
Egli M; Usman N; Rich A
Biochemistry; 1993 Apr; 32(13):3221-37. PubMed ID: 7681688
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]
