374 related articles for article (PubMed ID: 16251482)
1. Cisplatin-induced hepatotoxicity is enhanced by elevated expression of cytochrome P450 2E1.
Lu Y; Cederbaum AI
Toxicol Sci; 2006 Feb; 89(2):515-23. PubMed ID: 16251482
[TBL] [Abstract][Full Text] [Related]
2. Cytochrome P450 2E1 potentiates ethanol induction of hypoxia and HIF-1α in vivo.
Wang X; Wu D; Yang L; Gan L; Cederbaum AI
Free Radic Biol Med; 2013 Oct; 63():175-86. PubMed ID: 23669278
[TBL] [Abstract][Full Text] [Related]
3. The liver-selective nitric oxide donor O2-vinyl 1-(pyrrolidin-1-yl)diazen-1-ium-1,2-diolate (V-PYRRO/NO) protects HepG2 cells against cytochrome P450 2E1-dependent toxicity.
Gong P; Cederbaum AI; Nieto N
Mol Pharmacol; 2004 Jan; 65(1):130-8. PubMed ID: 14722244
[TBL] [Abstract][Full Text] [Related]
4. The mode of cisplatin-induced cell death in CYP2E1-overexpressing HepG2 cells: modulation by ERK, ROS, glutathione, and thioredoxin.
Lu Y; Cederbaum A
Free Radic Biol Med; 2007 Oct; 43(7):1061-75. PubMed ID: 17761302
[TBL] [Abstract][Full Text] [Related]
5. S-adenosyl-L-methionine attenuates hepatotoxicity induced by agonistic Jo2 Fas antibody following CYP2E1 induction in mice.
Wang X; Cederbaum AI
J Pharmacol Exp Ther; 2006 Apr; 317(1):44-52. PubMed ID: 16373529
[TBL] [Abstract][Full Text] [Related]
6. Heme oxygenase-1 protects HepG2 cells against cytochrome P450 2E1-dependent toxicity.
Gong P; Cederbaum AI; Nieto N
Free Radic Biol Med; 2004 Feb; 36(3):307-18. PubMed ID: 15036350
[TBL] [Abstract][Full Text] [Related]
7. Increased toxicity by transforming growth factor-beta 1 in liver cells overexpressing CYP2E1.
Zhuge J; Cederbaum AI
Free Radic Biol Med; 2006 Oct; 41(7):1100-12. PubMed ID: 16962935
[TBL] [Abstract][Full Text] [Related]
8. Increased prooxidant production and enhanced susceptibility to glutathione depletion in HepG2 cells co-expressing HCV core protein and CYP2E1.
Wen F; Abdalla MY; Aloman C; Xiang J; Ahmad IM; Walewski J; McCormick ML; Brown KE; Branch AD; Spitz DR; Britigan BE; Schmidt WN
J Med Virol; 2004 Feb; 72(2):230-40. PubMed ID: 14695664
[TBL] [Abstract][Full Text] [Related]
9. Nrf2 and antioxidant defense against CYP2E1 toxicity.
Cederbaum AI
Subcell Biochem; 2013; 67():105-30. PubMed ID: 23400918
[TBL] [Abstract][Full Text] [Related]
10. Geldanamycin, an inhibitor of Hsp90, potentiates cytochrome P4502E1-mediated toxicity in HepG2 cells.
Dey A; Cederbaum AI
J Pharmacol Exp Ther; 2006 Jun; 317(3):1391-9. PubMed ID: 16513847
[TBL] [Abstract][Full Text] [Related]
11. Opposite action of S-adenosyl methionine and its metabolites on CYP2E1-mediated toxicity in pyrazole-induced rat hepatocytes and HepG2 E47 cells.
Wu D; Cederbaum AI
Am J Physiol Gastrointest Liver Physiol; 2006 Apr; 290(4):G674-84. PubMed ID: 16306132
[TBL] [Abstract][Full Text] [Related]
12. Induction of cytochrome P450 2E1 increases hepatotoxicity caused by Fas agonistic Jo2 antibody in mice.
Wang X; Lu Y; Cederbaum AI
Hepatology; 2005 Aug; 42(2):400-10. PubMed ID: 16025513
[TBL] [Abstract][Full Text] [Related]
13. Nrf2 and antioxidant defense against CYP2E1 toxicity.
Cederbaum A
Expert Opin Drug Metab Toxicol; 2009 Oct; 5(10):1223-44. PubMed ID: 19671018
[TBL] [Abstract][Full Text] [Related]
14. Differential role of ethanol and acetaldehyde in the induction of oxidative stress in HEP G2 cells: effect on transcription factors AP-1 and NF-kappaB.
Román J; Colell A; Blasco C; Caballeria J; Parés A; Rodés J; Fernández-Checa JC
Hepatology; 1999 Dec; 30(6):1473-80. PubMed ID: 10573527
[TBL] [Abstract][Full Text] [Related]
15. Serum deprivation-induced HepG2 cell death is potentiated by CYP2E1.
Zhuge J; Cederbaum AI
Free Radic Biol Med; 2006 Jan; 40(1):63-74. PubMed ID: 16337880
[TBL] [Abstract][Full Text] [Related]
16. Induction of cytochrome P450 2E1 [corrected] promotes liver injury in ob/ob mice.
Dey A; Cederbaum AI
Hepatology; 2007 Jun; 45(6):1355-65. PubMed ID: 17538970
[TBL] [Abstract][Full Text] [Related]
17. Inhibition of autophagy promotes CYP2E1-dependent toxicity in HepG2 cells via elevated oxidative stress, mitochondria dysfunction and activation of p38 and JNK MAPK.
Wu D; Cederbaum AI
Redox Biol; 2013; 1(1):552-65. PubMed ID: 24273738
[TBL] [Abstract][Full Text] [Related]
18. Nrf2 is increased by CYP2E1 in rodent liver and HepG2 cells and protects against oxidative stress caused by CYP2E1.
Gong P; Cederbaum AI
Hepatology; 2006 Jan; 43(1):144-53. PubMed ID: 16374848
[TBL] [Abstract][Full Text] [Related]
19. Green tea polyphenol epigallocatechin-3-gallate protects HepG2 cells against CYP2E1-dependent toxicity.
Jimenez-Lopez JM; Cederbaum AI
Free Radic Biol Med; 2004 Feb; 36(3):359-70. PubMed ID: 15036355
[TBL] [Abstract][Full Text] [Related]
20. Glutathione depletion in CYP2E1-expressing liver cells induces toxicity due to the activation of p38 mitogen-activated protein kinase and reduction of nuclear factor-kappaB DNA binding activity.
Wu D; Cederbaum A
Mol Pharmacol; 2004 Sep; 66(3):749-60. PubMed ID: 15322268
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]