BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

374 related articles for article (PubMed ID: 16251482)

  • 1. Cisplatin-induced hepatotoxicity is enhanced by elevated expression of cytochrome P450 2E1.
    Lu Y; Cederbaum AI
    Toxicol Sci; 2006 Feb; 89(2):515-23. PubMed ID: 16251482
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Cytochrome P450 2E1 potentiates ethanol induction of hypoxia and HIF-1α in vivo.
    Wang X; Wu D; Yang L; Gan L; Cederbaum AI
    Free Radic Biol Med; 2013 Oct; 63():175-86. PubMed ID: 23669278
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The liver-selective nitric oxide donor O2-vinyl 1-(pyrrolidin-1-yl)diazen-1-ium-1,2-diolate (V-PYRRO/NO) protects HepG2 cells against cytochrome P450 2E1-dependent toxicity.
    Gong P; Cederbaum AI; Nieto N
    Mol Pharmacol; 2004 Jan; 65(1):130-8. PubMed ID: 14722244
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The mode of cisplatin-induced cell death in CYP2E1-overexpressing HepG2 cells: modulation by ERK, ROS, glutathione, and thioredoxin.
    Lu Y; Cederbaum A
    Free Radic Biol Med; 2007 Oct; 43(7):1061-75. PubMed ID: 17761302
    [TBL] [Abstract][Full Text] [Related]  

  • 5. S-adenosyl-L-methionine attenuates hepatotoxicity induced by agonistic Jo2 Fas antibody following CYP2E1 induction in mice.
    Wang X; Cederbaum AI
    J Pharmacol Exp Ther; 2006 Apr; 317(1):44-52. PubMed ID: 16373529
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Heme oxygenase-1 protects HepG2 cells against cytochrome P450 2E1-dependent toxicity.
    Gong P; Cederbaum AI; Nieto N
    Free Radic Biol Med; 2004 Feb; 36(3):307-18. PubMed ID: 15036350
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Increased toxicity by transforming growth factor-beta 1 in liver cells overexpressing CYP2E1.
    Zhuge J; Cederbaum AI
    Free Radic Biol Med; 2006 Oct; 41(7):1100-12. PubMed ID: 16962935
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Increased prooxidant production and enhanced susceptibility to glutathione depletion in HepG2 cells co-expressing HCV core protein and CYP2E1.
    Wen F; Abdalla MY; Aloman C; Xiang J; Ahmad IM; Walewski J; McCormick ML; Brown KE; Branch AD; Spitz DR; Britigan BE; Schmidt WN
    J Med Virol; 2004 Feb; 72(2):230-40. PubMed ID: 14695664
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Nrf2 and antioxidant defense against CYP2E1 toxicity.
    Cederbaum AI
    Subcell Biochem; 2013; 67():105-30. PubMed ID: 23400918
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Geldanamycin, an inhibitor of Hsp90, potentiates cytochrome P4502E1-mediated toxicity in HepG2 cells.
    Dey A; Cederbaum AI
    J Pharmacol Exp Ther; 2006 Jun; 317(3):1391-9. PubMed ID: 16513847
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Opposite action of S-adenosyl methionine and its metabolites on CYP2E1-mediated toxicity in pyrazole-induced rat hepatocytes and HepG2 E47 cells.
    Wu D; Cederbaum AI
    Am J Physiol Gastrointest Liver Physiol; 2006 Apr; 290(4):G674-84. PubMed ID: 16306132
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Induction of cytochrome P450 2E1 increases hepatotoxicity caused by Fas agonistic Jo2 antibody in mice.
    Wang X; Lu Y; Cederbaum AI
    Hepatology; 2005 Aug; 42(2):400-10. PubMed ID: 16025513
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Nrf2 and antioxidant defense against CYP2E1 toxicity.
    Cederbaum A
    Expert Opin Drug Metab Toxicol; 2009 Oct; 5(10):1223-44. PubMed ID: 19671018
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Differential role of ethanol and acetaldehyde in the induction of oxidative stress in HEP G2 cells: effect on transcription factors AP-1 and NF-kappaB.
    Román J; Colell A; Blasco C; Caballeria J; Parés A; Rodés J; Fernández-Checa JC
    Hepatology; 1999 Dec; 30(6):1473-80. PubMed ID: 10573527
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Serum deprivation-induced HepG2 cell death is potentiated by CYP2E1.
    Zhuge J; Cederbaum AI
    Free Radic Biol Med; 2006 Jan; 40(1):63-74. PubMed ID: 16337880
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Induction of cytochrome P450 2E1 [corrected] promotes liver injury in ob/ob mice.
    Dey A; Cederbaum AI
    Hepatology; 2007 Jun; 45(6):1355-65. PubMed ID: 17538970
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Inhibition of autophagy promotes CYP2E1-dependent toxicity in HepG2 cells via elevated oxidative stress, mitochondria dysfunction and activation of p38 and JNK MAPK.
    Wu D; Cederbaum AI
    Redox Biol; 2013; 1(1):552-65. PubMed ID: 24273738
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Nrf2 is increased by CYP2E1 in rodent liver and HepG2 cells and protects against oxidative stress caused by CYP2E1.
    Gong P; Cederbaum AI
    Hepatology; 2006 Jan; 43(1):144-53. PubMed ID: 16374848
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Green tea polyphenol epigallocatechin-3-gallate protects HepG2 cells against CYP2E1-dependent toxicity.
    Jimenez-Lopez JM; Cederbaum AI
    Free Radic Biol Med; 2004 Feb; 36(3):359-70. PubMed ID: 15036355
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Glutathione depletion in CYP2E1-expressing liver cells induces toxicity due to the activation of p38 mitogen-activated protein kinase and reduction of nuclear factor-kappaB DNA binding activity.
    Wu D; Cederbaum A
    Mol Pharmacol; 2004 Sep; 66(3):749-60. PubMed ID: 15322268
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.