BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

196 related articles for article (PubMed ID: 16254058)

  • 1. Reversing hypoxic cell chemoresistance in vitro using genetic and small molecule approaches targeting hypoxia inducible factor-1.
    Brown LM; Cowen RL; Debray C; Eustace A; Erler JT; Sheppard FC; Parker CA; Stratford IJ; Williams KJ
    Mol Pharmacol; 2006 Feb; 69(2):411-8. PubMed ID: 16254058
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Topotecan inhibits vascular endothelial growth factor production and angiogenic activity induced by hypoxia in human neuroblastoma by targeting hypoxia-inducible factor-1alpha and -2alpha.
    Puppo M; Battaglia F; Ottaviano C; Delfino S; Ribatti D; Varesio L; Bosco MC
    Mol Cancer Ther; 2008 Jul; 7(7):1974-84. PubMed ID: 18645007
    [TBL] [Abstract][Full Text] [Related]  

  • 3. HIF-1alpha modulation by topoisomerase inhibitors in non-small cell lung cancer cell lines.
    Choi YJ; Rho JK; Lee SJ; Jang WS; Lee SS; Kim CH; Lee JC
    J Cancer Res Clin Oncol; 2009 Aug; 135(8):1047-53. PubMed ID: 19148680
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Hypoxia induced paclitaxel resistance in human ovarian cancers via hypoxia-inducible factor 1alpha.
    Huang L; Ao Q; Zhang Q; Yang X; Xing H; Li F; Chen G; Zhou J; Wang S; Xu G; Meng L; Lu Y; Ma D
    J Cancer Res Clin Oncol; 2010 Mar; 136(3):447-56. PubMed ID: 19760195
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Expression of AGPAT2, an enzyme involved in the glycerophospholipid/triacylglycerol biosynthesis pathway, is directly regulated by HIF-1 and promotes survival and etoposide resistance of cancer cells under hypoxia.
    Triantafyllou EA; Georgatsou E; Mylonis I; Simos G; Paraskeva E
    Biochim Biophys Acta Mol Cell Biol Lipids; 2018 Sep; 1863(9):1142-1152. PubMed ID: 29908837
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Hypoxia-induced cytotoxic drug resistance in osteosarcoma is independent of HIF-1Alpha.
    Adamski J; Price A; Dive C; Makin G
    PLoS One; 2013; 8(6):e65304. PubMed ID: 23785417
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Lenticular cytoprotection. Part 1: the role of hypoxia inducible factors-1α and -2α and vascular endothelial growth factor in lens epithelial cell survival in hypoxia.
    Neelam S; Brooks MM; Cammarata PR
    Mol Vis; 2013; 19():1-15. PubMed ID: 23335846
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Identification of novel small molecule inhibitors of hypoxia-inducible factor-1 that differentially block hypoxia-inducible factor-1 activity and hypoxia-inducible factor-1alpha induction in response to hypoxic stress and growth factors.
    Chau NM; Rogers P; Aherne W; Carroll V; Collins I; McDonald E; Workman P; Ashcroft M
    Cancer Res; 2005 Jun; 65(11):4918-28. PubMed ID: 15930314
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Effects of lentivirus-mediated HIF-1alpha knockdown on hypoxia-related cisplatin resistance and their dependence on p53 status in fibrosarcoma cells.
    Hao J; Song X; Song B; Liu Y; Wei L; Wang X; Yu J
    Cancer Gene Ther; 2008 Jul; 15(7):449-55. PubMed ID: 18421307
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Targeting the PAS-A domain of HIF-1alpha for development of small molecule inhibitors of HIF-1.
    Park EJ; Kong D; Fisher R; Cardellina J; Shoemaker RH; Melillo G
    Cell Cycle; 2006 Aug; 5(16):1847-53. PubMed ID: 16861921
    [TBL] [Abstract][Full Text] [Related]  

  • 11. An Akt/hypoxia-inducible factor-1alpha/platelet-derived growth factor-BB autocrine loop mediates hypoxia-induced chemoresistance in liver cancer cells and tumorigenic hepatic progenitor cells.
    Lau CK; Yang ZF; Ho DW; Ng MN; Yeoh GC; Poon RT; Fan ST
    Clin Cancer Res; 2009 May; 15(10):3462-71. PubMed ID: 19447872
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Sestrin2 inhibits hypoxia-inducible factor-1α accumulation via AMPK-mediated prolyl hydroxylase regulation.
    Seo K; Seo S; Ki SH; Shin SM
    Free Radic Biol Med; 2016 Dec; 101():511-523. PubMed ID: 27840318
    [TBL] [Abstract][Full Text] [Related]  

  • 13. [Effect of hypoxia on the chemotherapeutic sensitivity of human ovarian cancer cells to paclitaxel and its mechanism].
    Huang L; Zhang QH; Ao QL; Xing H; Lu YP; Ma D
    Zhonghua Zhong Liu Za Zhi; 2007 Feb; 29(2):96-100. PubMed ID: 17645840
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Hypoxia-induced resistance to cisplatin and doxorubicin in non-small cell lung cancer is inhibited by silencing of HIF-1alpha gene.
    Song X; Liu X; Chi W; Liu Y; Wei L; Wang X; Yu J
    Cancer Chemother Pharmacol; 2006 Dec; 58(6):776-84. PubMed ID: 16532342
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Shikonin suppresses proliferation and induces cell cycle arrest through the inhibition of hypoxia-inducible factor-1α signaling.
    Li MY; Mi C; Wang KS; Wang Z; Zuo HX; Piao LX; Xu GH; Li X; Ma J; Jin X
    Chem Biol Interact; 2017 Aug; 274():58-67. PubMed ID: 28684144
    [TBL] [Abstract][Full Text] [Related]  

  • 16. [Impact of RNA interference targeting hypoxia-inducible factor-1alpha on chemosensitivity in esophageal squamous cell carcinoma cells under hypoxia].
    Wu XA; Sun Y; Fan QX; Wang LX; Wang RL; Zhang L
    Zhonghua Yi Xue Za Zhi; 2007 Oct; 87(37):2640-4. PubMed ID: 18162154
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Small interfering RNA targeting HIF-1α reduces hypoxia-dependent transcription and radiosensitizes hypoxic HT 1080 human fibrosarcoma cells in vitro.
    Staab A; Fleischer M; Loeffler J; Said HM; Katzer A; Plathow C; Einsele H; Flentje M; Vordermark D
    Strahlenther Onkol; 2011 Apr; 187(4):252-9. PubMed ID: 21437769
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The oxygen sensor factor-inhibiting hypoxia-inducible factor-1 controls expression of distinct genes through the bifunctional transcriptional character of hypoxia-inducible factor-1alpha.
    Dayan F; Roux D; Brahimi-Horn MC; Pouyssegur J; Mazure NM
    Cancer Res; 2006 Apr; 66(7):3688-98. PubMed ID: 16585195
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Antiapoptotic Effect of Gene Therapy with Recombinant Adenovirus Vector Containing Hypoxia-inducible Factor-1α after Cerebral Ischemia and Reperfusion in Rats.
    Yang ML; Tao T; Xu J; Liu Z; Xu D
    Chin Med J (Engl); 2017 Jul; 130(14):1700-1706. PubMed ID: 28685721
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Hydrogen sulfide inhibits hypoxia- but not anoxia-induced hypoxia-inducible factor 1 activation in a von hippel-lindau- and mitochondria-dependent manner.
    Kai S; Tanaka T; Daijo H; Harada H; Kishimoto S; Suzuki K; Takabuchi S; Takenaga K; Fukuda K; Hirota K
    Antioxid Redox Signal; 2012 Feb; 16(3):203-16. PubMed ID: 22004513
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.