150 related articles for article (PubMed ID: 16257201)
1. Privileged structure-based quinazolinone natural product-templated libraries: identification of novel tubulin polymerization inhibitors.
Liu JF; Wilson CJ; Ye P; Sprague K; Sargent K; Si Y; Beletsky G; Yohannes D; Ng SC
Bioorg Med Chem Lett; 2006 Feb; 16(3):686-90. PubMed ID: 16257201
[TBL] [Abstract][Full Text] [Related]
2. Synthesis and structure-activity relationships of 1-benzyl-4,5,6-trimethoxyindoles as a novel class of potent antimitotic agents.
Lai MJ; Kuo CC; Yeh TK; Hsieh HP; Chen LT; Pan WY; Hsu KY; Chang JY; Liou JP
ChemMedChem; 2009 Apr; 4(4):588-93. PubMed ID: 19266513
[TBL] [Abstract][Full Text] [Related]
3. Oxadiazole derivatives as a novel class of antimitotic agents: Synthesis, inhibition of tubulin polymerization, and activity in tumor cell lines.
Ouyang X; Piatnitski EL; Pattaropong V; Chen X; He HY; Kiselyov AS; Velankar A; Kawakami J; Labelle M; Smith L; Lohman J; Lee SP; Malikzay A; Fleming J; Gerlak J; Wang Y; Rosler RL; Zhou K; Mitelman S; Camara M; Surguladze D; Doody JF; Tuma MC
Bioorg Med Chem Lett; 2006 Mar; 16(5):1191-6. PubMed ID: 16377187
[TBL] [Abstract][Full Text] [Related]
4. Synthesis and biological evaluation of 2- and 3-aminobenzo[b]thiophene derivatives as antimitotic agents and inhibitors of tubulin polymerization.
Romagnoli R; Baraldi PG; Carrion MD; Lopez Cara C; Preti D; Fruttarolo F; Pavani MG; Tabrizi MA; Tolomeo M; Grimaudo S; Di Cristina A; Balzarini J; Hadfield JA; Brancale A; Hamel E
J Med Chem; 2007 May; 50(9):2273-7. PubMed ID: 17419607
[TBL] [Abstract][Full Text] [Related]
5. Indole, a core nucleus for potent inhibitors of tubulin polymerization.
Brancale A; Silvestri R
Med Res Rev; 2007 Mar; 27(2):209-38. PubMed ID: 16788980
[TBL] [Abstract][Full Text] [Related]
6. Identification of novel antimitotic agents acting at the tubulin level by computer-assisted evaluation of differential cytotoxicity data.
Paull KD; Lin CM; Malspeis L; Hamel E
Cancer Res; 1992 Jul; 52(14):3892-900. PubMed ID: 1617665
[TBL] [Abstract][Full Text] [Related]
7. Synthesis and biological evaluation of 1-methyl-2-(3',4',5'-trimethoxybenzoyl)-3-aminoindoles as a new class of antimitotic agents and tubulin inhibitors.
Romagnoli R; Baraldi PG; Sarkar T; Carrion MD; Cara CL; Cruz-Lopez O; Preti D; Tabrizi MA; Tolomeo M; Grimaudo S; Di Cristina A; Zonta N; Balzarini J; Brancale A; Hsieh HP; Hamel E
J Med Chem; 2008 Mar; 51(5):1464-8. PubMed ID: 18260616
[TBL] [Abstract][Full Text] [Related]
8. Design and synthesis of a quinazolinone natural product-templated library with cytotoxic activity.
Liu JF; Kaselj M; Isome Y; Ye P; Sargent K; Sprague K; Cherrak D; Wilson CJ; Si Y; Yohannes D; Ng SC
J Comb Chem; 2006; 8(1):7-10. PubMed ID: 16398546
[No Abstract] [Full Text] [Related]
9. Antimitotic activity of lobaric acid and a new benzofuran, sakisacaulon A from Stereocaulon sasakii.
Morita H; Tsuchiya T; Kishibe K; Noya S; Shiro M; Hirasawa Y
Bioorg Med Chem Lett; 2009 Jul; 19(13):3679-81. PubMed ID: 19481447
[TBL] [Abstract][Full Text] [Related]
10. Effects of alpha-substitutions on structure and biological activity of anticancer chalcones.
Lawrence NJ; Patterson RP; Ooi LL; Cook D; Ducki S
Bioorg Med Chem Lett; 2006 Nov; 16(22):5844-8. PubMed ID: 16949281
[TBL] [Abstract][Full Text] [Related]
11. Cellular analysis of disorazole C and structure-activity relationship of analogs of the natural product.
Wipf P; Graham TH; Vogt A; Sikorski RP; Ducruet AP; Lazo JS
Chem Biol Drug Des; 2006 Jan; 67(1):66-73. PubMed ID: 16492150
[TBL] [Abstract][Full Text] [Related]
12. Structure-based identification of the binding site for the hemiasterlin analogue HTI-286 on tubulin.
Ravi M; Zask A; Rush TS
Biochemistry; 2005 Dec; 44(48):15871-9. PubMed ID: 16313189
[TBL] [Abstract][Full Text] [Related]
13. Synthesis of novel diaryl ethers and their evaluation as antimitotic agents.
In JK; Lee MS; Yang JE; Kwak JH; Lee H; Boovanahalli SK; Lee K; Kim SJ; Moon SK; Lee S; Choi NS; Ahn SK; Jung JK
Bioorg Med Chem Lett; 2007 Mar; 17(6):1799-802. PubMed ID: 17276056
[TBL] [Abstract][Full Text] [Related]
14. Novel carbazole and acyl-indole antimitotics.
Barta TE; Barabasz AF; Foley BE; Geng L; Hall SE; Hanson GJ; Jenks M; Ma W; Rice JW; Veal J
Bioorg Med Chem Lett; 2009 Jun; 19(11):3078-80. PubMed ID: 19394222
[TBL] [Abstract][Full Text] [Related]
15. Tubulin-based antimitotic mechanism of E7974, a novel analogue of the marine sponge natural product hemiasterlin.
Kuznetsov G; TenDyke K; Towle MJ; Cheng H; Liu J; Marsh JP; Schiller SE; Spyvee MR; Yang H; Seletsky BM; Shaffer CJ; Marceau V; Yao Y; Suh EM; Campagna S; Fang FG; Kowalczyk JJ; Littlefield BA
Mol Cancer Ther; 2009 Oct; 8(10):2852-60. PubMed ID: 19825803
[TBL] [Abstract][Full Text] [Related]
16. Synthesis and biological evaluation of 6H-pyrido[2',1':2,3]imidazo[4,5-c]isoquinolin-5(6H)-ones as antimitotic agents and inhibitors of tubulin polymerization.
Meng T; Wang W; Zhang Z; Ma L; Zhang Y; Miao Z; Shen J
Bioorg Med Chem; 2014 Jan; 22(2):848-55. PubMed ID: 24360827
[TBL] [Abstract][Full Text] [Related]
17. Benzopyridooxathiazepine derivatives as novel potent antimitotic agents.
Gallet S; Flouquet N; Carato P; Pfeiffer B; Renard P; Léonce S; Pierré A; Berthelot P; Lebegue N
Bioorg Med Chem; 2009 Feb; 17(3):1132-8. PubMed ID: 19162484
[TBL] [Abstract][Full Text] [Related]
18. Synthesis and biological evaluation of cinnamido linked pyrrolo[2,1-c][1,4]benzodiazepines as antimitotic agents.
Kamal A; Balakishan G; Ramakrishna G; Shaik TB; Sreekanth K; Balakrishna M; Rajender ; Dastagiri D; Kalivendi SV
Eur J Med Chem; 2010 Sep; 45(9):3870-84. PubMed ID: 20554354
[TBL] [Abstract][Full Text] [Related]
19. Synthesis and biological activity of 7-phenyl-6,9-dihydro-3H-pyrrolo[3,2-f]quinolin-9-ones: a new class of antimitotic agents devoid of aromatase activity.
Gasparotto V; Castagliuolo I; Chiarelotto G; Pezzi V; Montanaro D; Brun P; Palù G; Viola G; Ferlin MG
J Med Chem; 2006 Mar; 49(6):1910-5. PubMed ID: 16539377
[TBL] [Abstract][Full Text] [Related]
20. Novel Natural Product- and Privileged Scaffold-Based Tubulin Inhibitors Targeting the Colchicine Binding Site.
Dong M; Liu F; Zhou H; Zhai S; Yan B
Molecules; 2016 Oct; 21(10):. PubMed ID: 27754459
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
