BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

359 related articles for article (PubMed ID: 16257523)

  • 1. Functional assays for screening GPCR targets.
    Thomsen W; Frazer J; Unett D
    Curr Opin Biotechnol; 2005 Dec; 16(6):655-65. PubMed ID: 16257523
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Innovation and greater probability of success in drug discovery and development -- from target to biomarkers.
    Kola I; Hazuda D
    Curr Opin Biotechnol; 2005 Dec; 16(6):644-6. PubMed ID: 16263257
    [No Abstract]   [Full Text] [Related]  

  • 3. Label-free optical biosensor: a tool for G protein-coupled receptors pharmacology profiling and inverse agonists identification.
    Lee PH
    J Recept Signal Transduct Res; 2009; 29(3-4):146-53. PubMed ID: 19594401
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Resonant waveguide grating biosensor for whole-cell GPCR assays.
    Fang Y; Ferrie AM; Tran E
    Methods Mol Biol; 2009; 552():239-52. PubMed ID: 19513654
    [TBL] [Abstract][Full Text] [Related]  

  • 5. G-protein-coupled receptors in drug discovery: nanosizing using cell-free technologies and molecular biology approaches.
    Leifert WR; Aloia AL; Bucco O; Glatz RV; McMurchie EJ
    J Biomol Screen; 2005 Dec; 10(8):765-79. PubMed ID: 16234342
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The 7 TM G-protein-coupled receptor target family.
    Jacoby E; Bouhelal R; Gerspacher M; Seuwen K
    ChemMedChem; 2006 Aug; 1(8):761-82. PubMed ID: 16902930
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Assessing GPCR activation using protein complementation: a novel technique for HTS.
    Eglen RM
    Biochem Soc Trans; 2007 Aug; 35(Pt 4):746-8. PubMed ID: 17635139
    [TBL] [Abstract][Full Text] [Related]  

  • 8. G-protein-coupled receptor-focused drug discovery using a target class platform approach.
    Heilker R; Wolff M; Tautermann CS; Bieler M
    Drug Discov Today; 2009 Mar; 14(5-6):231-40. PubMed ID: 19121411
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Real-time monitoring of morphological changes in living cells by electronic cell sensor arrays: an approach to study G protein-coupled receptors.
    Yu N; Atienza JM; Bernard J; Blanc S; Zhu J; Wang X; Xu X; Abassi YA
    Anal Chem; 2006 Jan; 78(1):35-43. PubMed ID: 16383308
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Cell-based assays in GPCR drug discovery. In this issue.
    Biotechnol J; 2008 Apr; 3(4):430. PubMed ID: 18412181
    [No Abstract]   [Full Text] [Related]  

  • 11. Ligand screening system using fusion proteins of G protein-coupled receptors with G protein alpha subunits.
    Suga H; Haga T
    Neurochem Int; 2007; 51(2-4):140-64. PubMed ID: 17659814
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Optical techniques to analyze real-time activation and signaling of G-protein-coupled receptors.
    Lohse MJ; Nikolaev VO; Hein P; Hoffmann C; Vilardaga JP; Bünemann M
    Trends Pharmacol Sci; 2008 Mar; 29(3):159-65. PubMed ID: 18262662
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cell-based assays in GPCR drug discovery.
    Siehler S
    Biotechnol J; 2008 Apr; 3(4):471-83. PubMed ID: 18383022
    [TBL] [Abstract][Full Text] [Related]  

  • 14. GloSensor assay for discovery of GPCR-selective ligands.
    Kumar BA; Kumari P; Sona C; Yadav PN
    Methods Cell Biol; 2017; 142():27-50. PubMed ID: 28964338
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The structure and dynamics of GPCR oligomers: a new focus in models of cell-signaling mechanisms and drug design.
    Filizola M; Weinstein H
    Curr Opin Drug Discov Devel; 2005 Sep; 8(5):577-84. PubMed ID: 16159019
    [TBL] [Abstract][Full Text] [Related]  

  • 16. G protein-coupled receptor internalization assays in the high-content screening format.
    Haasen D; Schnapp A; Valler MJ; Heilker R
    Methods Enzymol; 2006; 414():121-39. PubMed ID: 17110190
    [TBL] [Abstract][Full Text] [Related]  

  • 17. From purified GPCRs to drug discovery: the promise of protein-based methodologies.
    Alkhalfioui F; Magnin T; Wagner R
    Curr Opin Pharmacol; 2009 Oct; 9(5):629-35. PubMed ID: 19443270
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Cell imaging assays for G protein-coupled receptor internalization: application to high-throughput screening.
    Lee S; Howell B; Kunapuli P
    Methods Enzymol; 2006; 414():79-98. PubMed ID: 17110188
    [TBL] [Abstract][Full Text] [Related]  

  • 19. New approaches to in-cell detection of protein activity: genetically encoded chemiluminescence probes pave the way to robust HTS assays.
    Hodgson L
    ACS Chem Biol; 2008 Jun; 3(6):335-7. PubMed ID: 18570352
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Bioinformatics-based discovery and identification of new biologically active peptides for GPCR deorphanization.
    Colette J; Avé E; Grenier-Boley B; Coquel AS; Lesellier K; Puget K
    J Pept Sci; 2007 Sep; 13(9):568-74. PubMed ID: 17694568
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.