These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

134 related articles for article (PubMed ID: 16258850)

  • 1. Differentially expressed genes in transgenic mice carrying human mutant presenilin-2 (N141I): correlation of selenoprotein M with Alzheimer's disease.
    Hwang DY; Cho JS; Oh JH; Shim SB; Jee SW; Lee SH; Seo SJ; Lee SK; Lee SH; Kim YK
    Neurochem Res; 2005 Aug; 30(8):1009-19. PubMed ID: 16258850
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Changes in presenilin 2-binding Wnt proteins, behavior, amyloid-beta 42, gamma-secretase activity, and testosterone sensitivity in transgenic mice coexpressing tetracycline-controlled transactivator and human mutant presenilin 2.
    Hwang DY; Cho JS; Kim CK; Shim SB; Jee SW; Lee SH; Seo SJ; Choi SY; Kim YK
    Neuromolecular Med; 2006; 8(3):415-32. PubMed ID: 16775391
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Increased apoptosis arising from increased expression of the Alzheimer's disease-associated presenilin-2 mutation (N141I).
    Janicki S; Monteiro MJ
    J Cell Biol; 1997 Oct; 139(2):485-95. PubMed ID: 9334350
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Analysis of differentially expressed genes in early- and late-stage APPsw-transgenic and normal mice using cDNA microarray.
    Jee SW; Cho JS; Kim CK; Hwang DY; Shim SB; Lee SH; Sin JS; Kim YS; Park JH; Lee SH; Choi SY; Kim YK
    Int J Mol Med; 2007 Mar; 19(3):461-8. PubMed ID: 17273795
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Alzheimer's phenotypes induced by overexpression of human presenilin 2 mutant proteins stimulate significant changes in key factors of glucose metabolism.
    Lee YJ; Kim JE; Hwang IS; Kwak MH; Lee JH; Jung YJ; An BS; Kwon HS; Kim BC; Kim SJ; Kim JM; Hwang DY
    Mol Med Rep; 2013 May; 7(5):1571-8. PubMed ID: 23546527
    [TBL] [Abstract][Full Text] [Related]  

  • 6. cDNA microarray-based analysis of differentially expressed genes in transgenic brains expressing NSE-controlled APPsw.
    Jee SW; Cho JS; Oh JH; Shim SB; Hwang DY; Lee SH; Song YS; Lee SH; Kim YK
    Int J Mol Med; 2005 Oct; 16(4):547-52. PubMed ID: 16142385
    [TBL] [Abstract][Full Text] [Related]  

  • 7. ERK activation induced by selenium treatment significantly downregulates beta/gamma-secretase activity and Tau phosphorylation in the transgenic rat overexpressing human selenoprotein M.
    Yim SY; Chae KR; Shim SB; Hong JT; Park JY; Lee CY; Son HJ; Sheen YY; Hwang DY
    Int J Mol Med; 2009 Jul; 24(1):91-6. PubMed ID: 19513540
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Early changes in behavior deficits, amyloid beta-42 deposits and MAPK activation in doubly transgenic mice co-expressing NSE-controlled human mutant PS2 and APPsw.
    Hwang DY; Cho JS; Oh JH; Shim SB; Jee SW; Lee SH; Seo SJ; Song CW; Lee SH; Kim YK
    Cell Mol Neurobiol; 2005 Aug; 25(5):881-98. PubMed ID: 16133940
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inorganic arsenic modulates the expression of selenoproteins in mouse embryonic stem cell.
    Huang Z; Li J; Zhang S; Zhang X
    Toxicol Lett; 2009 Jun; 187(2):69-76. PubMed ID: 19429247
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Proteomic analysis of serum proteins in triple transgenic Alzheimer's disease mice: implications for identifying biomarkers for use to screen potential candidate therapeutic drugs for early Alzheimer's disease.
    Sui X; Ren X; Huang P; Li S; Ma Q; Ying M; Ni J; Liu J; Yang X
    J Alzheimers Dis; 2014; 40(3):575-86. PubMed ID: 24496070
    [TBL] [Abstract][Full Text] [Related]  

  • 11. APP processing and amyloid deposition in mice haplo-insufficient for presenilin 1.
    Jankowsky JL; Slunt HH; Gonzales V; Jenkins NA; Copeland NG; Borchelt DR
    Neurobiol Aging; 2004 Aug; 25(7):885-92. PubMed ID: 15212842
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Overexpression of human selenoprotein M differentially regulates the concentrations of antioxidants and H2O2, the activity of antioxidant enzymes, and the composition of white blood cells in a transgenic rat.
    Hwang DY; Sin JS; Kim MS; Yim SY; Kim YK; Kim CK; Kim BG; Shim SB; Jee SW; Lee SH; Bae CJ; Lee BC; Jang MK; Cho JS; Chae KR
    Int J Mol Med; 2008 Feb; 21(2):169-79. PubMed ID: 18204783
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Overexpression of N141I PS2 increases γ-secretase activity through up-regulation of Presenilin and Pen-2 in brain mitochondria of NSE/hPS2m transgenic mice.
    Yun WB; Park JJ; Kim JE; Sung JE; Lee HA; Lee JH; Bae CJ; Hwang DY
    Lab Anim Res; 2016 Dec; 32(4):249-256. PubMed ID: 28053619
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Aberrant presenilin-1 expression downregulates LDL receptor-related protein (LRP): is LRP central to Alzheimer's disease pathogenesis?
    Van Uden E; Carlson G; St George-Hyslop P; Westaway D; Orlando R; Mallory M; Rockenstein E; Masliah E
    Mol Cell Neurosci; 1999 Aug; 14(2):129-40. PubMed ID: 10479411
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Mutant presenilin 2 increases acetylcholinesterase activity in neuronal cells.
    Nguyen HN; Hwang DY; Kim YK; Yoon DY; Kim JH; Lee MS; Lee MK; Yun YP; Oh KW; Hong JT
    Arch Pharm Res; 2005 Sep; 28(9):1073-8. PubMed ID: 16212240
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Transcriptome differences between the frontal cortex and hippocampus of wild-type and humanized presenilin-1 transgenic mice.
    Unger T; Korade Z; Lazarov O; Terrano D; Schor NF; Sisodia SS; Mirnics K
    Am J Geriatr Psychiatry; 2005 Dec; 13(12):1041-51. PubMed ID: 16319296
    [TBL] [Abstract][Full Text] [Related]  

  • 17. RNA-Seq analysis of frontal cortex and cerebellum from 5XFAD mice at early stage of disease pathology.
    Kim KH; Moon M; Yu SB; Mook-Jung I; Kim JI
    J Alzheimers Dis; 2012; 29(4):793-808. PubMed ID: 22507954
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Distinct Expression of Long Non-Coding RNAs in an Alzheimer's Disease Model.
    Lee DY; Moon J; Lee ST; Jung KH; Park DK; Yoo JS; Sunwoo JS; Byun JI; Shin JW; Jeon D; Jung KY; Kim M; Lee SK; Chu K
    J Alzheimers Dis; 2015; 45(3):837-49. PubMed ID: 25624420
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Inhibition of cyclooxygenase as potential novel therapeutic strategy in N141I presenilin-2 familial Alzheimer's disease.
    Qin W; Peng Y; Ksiezak-Reding H; Ho L; Stetka B; Lovati E; Pasinetti GM
    Mol Psychiatry; 2006 Feb; 11(2):172-81. PubMed ID: 16331303
    [TBL] [Abstract][Full Text] [Related]  

  • 20. [Alzheimer's disease due to presenilin mutations].
    Tabira T
    Nihon Rinsho; 2004 Jan; 62 Suppl():90-4. PubMed ID: 15011327
    [No Abstract]   [Full Text] [Related]  

    [Next]    [New Search]
    of 7.