BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

220 related articles for article (PubMed ID: 16259761)

  • 1. Design and synthesis of long-chain arylpiperazines with mixed affinity for serotonin transporter (SERT) and 5-HT(1A) receptor.
    Perrone R; Berardi F; Colabufo NA; Lacivita E; Larizza C; Leopoldo M; Tortorella V
    J Pharm Pharmacol; 2005 Oct; 57(10):1319-27. PubMed ID: 16259761
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structure-affinity relationship study on N-(1,2,3,4-tetrahydronaphthalen-1-yl)-4-aryl-1-piperazinealkylamides, a new class of 5-hydroxytryptamine7 receptor agents.
    Leopoldo M; Berardi F; Colabufo NA; Contino M; Lacivita E; Niso M; Perrone R; Tortorella V
    J Med Chem; 2004 Dec; 47(26):6616-24. PubMed ID: 15588097
    [TBL] [Abstract][Full Text] [Related]  

  • 3. New arylpiperazine 5-HT(1A) receptor ligands containing the pyrimido[2,1-f]purine fragment: synthesis, in vitro, and in vivo pharmacological evaluation.
    Jurczyk S; Kołaczkowski M; Maryniak E; Zajdel P; Pawłowski M; Tatarczyńska E; Kłodzińska A; Chojnacka-Wójcik E; Bojarski AJ; Charakchieva-Minol S; Duszyńska B; Nowak G; Maciag D
    J Med Chem; 2004 May; 47(10):2659-66. PubMed ID: 15115407
    [TBL] [Abstract][Full Text] [Related]  

  • 4. New 5-hydroxytryptamine(1A) receptor ligands containing a norbornene nucleus: synthesis and in vitro pharmacological evaluation.
    Fiorino F; Perissutti E; Severino B; Santagada V; Cirillo D; Terracciano S; Massarelli P; Bruni G; Collavoli E; Renner C; Caliendo G
    J Med Chem; 2005 Aug; 48(17):5495-503. PubMed ID: 16107148
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Allosteric modulation of 5-HT(1A) receptors by zinc: Binding studies.
    Barrondo S; Sallés J
    Neuropharmacology; 2009 Feb; 56(2):455-62. PubMed ID: 18951909
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Studies on 1-arylpiperazine derivatives with affinity for rat 5-HT7 and 5-HT1A receptors.
    Leopoldo M; Berardi F; Colabufo NA; Contino M; Lacivita E; Perrone R; Tortorella V
    J Pharm Pharmacol; 2004 Feb; 56(2):247-55. PubMed ID: 15005884
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Differential effects of the 5-hydroxytryptamine (5-HT)1A receptor inverse agonists Rec 27/0224 and Rec 27/0074 on electrophysiological responses to 5-HT1A receptor activation in rat dorsal raphe nucleus and hippocampus in vitro.
    Corradetti R; Mlinar B; Falsini C; Pugliese AM; Cilia A; Destefani C; Testa R
    J Pharmacol Exp Ther; 2005 Oct; 315(1):109-17. PubMed ID: 15951403
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Novel class of arylpiperazines containing N-acylated amino acids: their synthesis, 5-HT1A, 5-HT2A receptor affinity, and in vivo pharmacological evaluation.
    Zajdel P; Subra G; Bojarski AJ; Duszyńska B; Tatarczyńska E; Nikiforuk A; Chojnacka-Wójcik E; Pawłowski M; Martinez J
    Bioorg Med Chem; 2007 Apr; 15(8):2907-19. PubMed ID: 17321139
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Stress-induced hyperthermia and basal body temperature are mediated by different 5-HT(1A) receptor populations: a study in SERT knockout rats.
    Olivier JD; Cools AR; Olivier B; Homberg JR; Cuppen E; Ellenbroek BA
    Eur J Pharmacol; 2008 Aug; 590(1-3):190-7. PubMed ID: 18606402
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Benzimidazole derivatives. Part 5: design and synthesis of new benzimidazole-arylpiperazine derivatives acting as mixed 5-HT1A/5-HT3 ligands.
    López-Rodríguez ML; Benhamú B; Morcillo MJ; Tejada I; Avila D; Marco I; Schiapparelli L; Frechilla D; Del Río J
    Bioorg Med Chem; 2004 Oct; 12(19):5181-91. PubMed ID: 15351401
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Indolebutylamines as selective 5-HT(1A) agonists.
    Heinrich T; Böttcher H; Bartoszyk GD; Greiner HE; Seyfried CA; Van Amsterdam C
    J Med Chem; 2004 Sep; 47(19):4677-83. PubMed ID: 15341483
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synthesis and molecular modeling of new 1-aryl-3-[4-arylpiperazin-1-yl]-1-propane derivatives with high affinity at the serotonin transporter and at 5-HT(1A) receptors.
    Orús L; Pérez-Silanes S; Oficialdegui AM; Martínez-Esparza J; Del Castillo JC; Mourelle M; Langer T; Guccione S; Donzella G; Krovat EM; Poptodorov K; Lasheras B; Ballaz S; Hervías I; Tordera R; Del Río J; Monge A
    J Med Chem; 2002 Sep; 45(19):4128-39. PubMed ID: 12213056
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Studies toward the discovery of the next generation of antidepressants. Part 6: Dual 5-HT1A receptor and serotonin transporter affinity within a class of arylpiperazinyl-cyclohexyl indole derivatives.
    Zhou D; Zhou P; Evrard DA; Meagher K; Webb M; Harrison BL; Huryn DM; Golembieski J; Hornby GA; Schechter LE; Smith DL; Andree TH; Mewshaw RE
    Bioorg Med Chem; 2008 Jul; 16(14):6707-23. PubMed ID: 18571421
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structure-affinity relationship studies on arylpiperazine derivatives related to quipazine as serotonin transporter ligands. Molecular basis of the selectivity SERT/5HT3 receptor.
    Cappelli A; Giuliani G; Gallelli A; Valenti S; Anzini M; Mennuni L; Makovec F; Cupello A; Vomero S
    Bioorg Med Chem; 2005 May; 13(10):3455-60. PubMed ID: 15848758
    [TBL] [Abstract][Full Text] [Related]  

  • 15. 1,3-Dioxolane-based ligands as rigid analogues of naftopidil: structure-affinity/activity relationships at alpha1 and 5-HT1A receptors.
    Sorbi C; Franchini S; Tait A; Prandi A; Gallesi R; Angeli P; Marucci G; Pirona L; Poggesi E; Brasili L
    ChemMedChem; 2009 Mar; 4(3):393-9. PubMed ID: 19152363
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Studies toward the discovery of the next generation of antidepressants. 3. Dual 5-HT1A and serotonin transporter affinity within a class of N-aryloxyethylindolylalkylamines.
    Mewshaw RE; Zhou D; Zhou P; Shi X; Hornby G; Spangler T; Scerni R; Smith D; Schechter LE; Andree TH
    J Med Chem; 2004 Jul; 47(15):3823-42. PubMed ID: 15239661
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis, anticonvulsant activity and 5-HT1A, 5-HT2A receptor affinity of new N-[(4-arylpiperazin-1-yl)-alkyl] derivatives of 2-azaspiro[4.4]nonane and [4.5]decane-1,3-dione.
    Obniska J; Kołaczkowski M; Bojarski AJ; Duszyńska B
    Eur J Med Chem; 2006 Jul; 41(7):874-81. PubMed ID: 16600439
    [TBL] [Abstract][Full Text] [Related]  

  • 18. N-[omega-[4-(2-methoxyphenyl)-1-piperazinyl]alkyl]-2-quinolinamines as high-affinity fluorescent 5-HT1A receptor ligands.
    Lacivita E; Leopoldo M
    J Med Chem; 2008 Mar; 51(5):1492-5. PubMed ID: 18269229
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Role of peripheral 5-HT1A receptors in detrusor over activity associated with partial bladder outlet obstruction in female rats.
    Mittra S; Malhotra S; Naruganahalli KS; Chugh A
    Eur J Pharmacol; 2007 Apr; 561(1-3):189-93. PubMed ID: 17320854
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis and pharmacological evaluation of new arylpiperazines N-[4-[4-(aryl) piperazine-1-yl]-phenyl]-amine derivatives: putative role of 5-HT1A receptors.
    Khatri M; Rai SK; Alam S; Vij A; Tiwari M
    Bioorg Med Chem; 2009 Mar; 17(5):1890-7. PubMed ID: 19223188
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.