These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

77 related articles for article (PubMed ID: 16260035)

  • 1. Depsipeptide-resistant KU812 cells show reversible P-glycoprotein expression, hyper-acetylated histones, and modulated gene expression profile.
    Yamada H; Arakawa Y; Saito S; Agawa M; Kano Y; Horiguchi-Yamada J
    Leuk Res; 2006 Jun; 30(6):723-34. PubMed ID: 16260035
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Involvement of extracellular signal-regulated kinase activation in human osteosarcoma cell resistance to the histone deacetylase inhibitor FK228 [(1S,4S,7Z,10S,16E,21R)-7-ethylidene-4,21-bis(propan-2-yl)-2-oxa-12,13-dithia-5,8,20,23-tetraazabicyclo[8.7.6]tricos-16-ene-3,6,9,19,22-pentone].
    Matsubara H; Watanabe M; Imai T; Yui Y; Mizushima Y; Hiraumi Y; Kamitsuji Y; Watanabe K; Nishijo K; Toguchida J; Nakahata T; Adachi S
    J Pharmacol Exp Ther; 2009 Mar; 328(3):839-48. PubMed ID: 19073909
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Histone deacetylase 1 gene expression and sensitization of multidrug-resistant neuroblastoma cell lines to cytotoxic agents by depsipeptide.
    Keshelava N; Davicioni E; Wan Z; Ji L; Sposto R; Triche TJ; Reynolds CP
    J Natl Cancer Inst; 2007 Jul; 99(14):1107-19. PubMed ID: 17623797
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Defining the role of gene regulation in resistance to HDAC inhibitors--mechanisms beyond P-glycoprotein.
    Glaser KB
    Leuk Res; 2006 Jun; 30(6):651-2. PubMed ID: 16376987
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Histone deacetylase inhibitor FK228 activates tumor suppressor Prdx1 with apoptosis induction in esophageal cancer cells.
    Hoshino I; Matsubara H; Hanari N; Mori M; Nishimori T; Yoneyama Y; Akutsu Y; Sakata H; Matsushita K; Seki N; Ochiai T
    Clin Cancer Res; 2005 Nov; 11(21):7945-52. PubMed ID: 16278420
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Depsipeptide a histone deacetlyase inhibitor down regulates levels of matrix metalloproteinases 2 and 9 mRNA and protein expressions in lung cancer cells (A549).
    Vinodhkumar R; Song YS; Ravikumar V; Ramakrishnan G; Devaki T
    Chem Biol Interact; 2007 Feb; 165(3):220-9. PubMed ID: 17240363
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Chemoresistance to depsipeptide FK228 [(E)-(1S,4S,10S,21R)-7-[(Z)-ethylidene]-4,21-diisopropyl-2-oxa-12,13-dithia-5,8,20,23-tetraazabicyclo[8,7,6]-tricos-16-ene-3,6,9,22-pentanone] is mediated by reversible MDR1 induction in human cancer cell lines.
    Xiao JJ; Huang Y; Dai Z; Sadée W; Chen J; Liu S; Marcucci G; Byrd J; Covey JM; Wright J; Grever M; Chan KK
    J Pharmacol Exp Ther; 2005 Jul; 314(1):467-75. PubMed ID: 15833893
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Combined treatment of P-gp-positive L1210/VCR cells by verapamil and all-trans retinoic acid induces down-regulation of P-glycoprotein expression and transport activity.
    Sulová Z; Macejová D; Seres M; Sedlák J; Brtko J; Breier A
    Toxicol In Vitro; 2008 Feb; 22(1):96-105. PubMed ID: 17920233
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Differential modulation of nuclear texture, histone acetylation, and MDR1 gene expression in human drug-sensitive and -resistant OV1 cell lines.
    Yatouji S; El-Khoury V; Trentesaux C; Trussardi-Regnier A; Benabid R; Bontems F; Dufer J
    Int J Oncol; 2007 Apr; 30(4):1003-9. PubMed ID: 17332941
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Decreased acetylation of histone H3 in renal cell carcinoma: a potential target of histone deacetylase inhibitors.
    Kanao K; Mikami S; Mizuno R; Shinojima T; Murai M; Oya M
    J Urol; 2008 Sep; 180(3):1131-6. PubMed ID: 18639283
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The histone deacetylase inhibitor trichostatin A downregulates human MDR1 (ABCB1) gene expression by a transcription-dependent mechanism in a drug-resistant small cell lung carcinoma cell line model.
    El-Khoury V; Breuzard G; Fourré N; Dufer J
    Br J Cancer; 2007 Aug; 97(4):562-73. PubMed ID: 17667922
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A putative role for histone deacetylase in the differentiation of human erythroid cells.
    Fujieda A; Katayama N; Ohishi K; Yamamura K; Shibasaki T; Sugimoto Y; Miyata E; Nishi K; Masuya M; Ueda H; Nakajima H; Shiku H
    Int J Oncol; 2005 Sep; 27(3):743-8. PubMed ID: 16077924
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Evaluation of the antitumor efficacy, pharmacokinetics, and pharmacodynamics of the histone deacetylase inhibitor depsipeptide in childhood cancer models in vivo.
    Graham C; Tucker C; Creech J; Favours E; Billups CA; Liu T; Fouladi M; Freeman BB; Stewart CF; Houghton PJ
    Clin Cancer Res; 2006 Jan; 12(1):223-34. PubMed ID: 16397046
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Romidepsin (depsipeptide) induced cell cycle arrest, apoptosis and histone hyperacetylation in lung carcinoma cells (A549) are associated with increase in p21 and hypophosphorylated retinoblastoma proteins expression.
    Vinodhkumar R; Song YS; Devaki T
    Biomed Pharmacother; 2008 Feb; 62(2):85-93. PubMed ID: 17644301
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Marker genes to predict sensitivity to FK228, a histone deacetylase inhibitor.
    Sasakawa Y; Naoe Y; Sogo N; Inoue T; Sasakawa T; Matsuo M; Manda T; Mutoh S
    Biochem Pharmacol; 2005 Feb; 69(4):603-16. PubMed ID: 15670579
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Proteomic analysis identifies protein targets responsible for depsipeptide sensitivity in tumor cells.
    Chen G; Li A; Zhao M; Gao Y; Zhou T; Xu Y; Du Z; Zhang X; Yu X
    J Proteome Res; 2008 Jul; 7(7):2733-42. PubMed ID: 18549279
    [TBL] [Abstract][Full Text] [Related]  

  • 17. FK228 (depsipeptide): a HDAC inhibitor with pleiotropic antitumor activities.
    Konstantinopoulos PA; Vandoros GP; Papavassiliou AG
    Cancer Chemother Pharmacol; 2006 Nov; 58(5):711-5. PubMed ID: 16435156
    [TBL] [Abstract][Full Text] [Related]  

  • 18. REIC/Dkk-3 overexpression downregulates P-glycoprotein in multidrug-resistant MCF7/ADR cells and induces apoptosis in breast cancer.
    Kawasaki K; Watanabe M; Sakaguchi M; Ogasawara Y; Ochiai K; Nasu Y; Doihara H; Kashiwakura Y; Huh NH; Kumon H; Date H
    Cancer Gene Ther; 2009 Jan; 16(1):65-72. PubMed ID: 18654608
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Downregulation of taurine uptake in multidrug resistant Ehrlich ascites tumor cells.
    Poulsen KA; Litman T; Eriksen J; Mollerup J; Lambert IH
    Amino Acids; 2002 Jun; 22(4):333-50. PubMed ID: 12107761
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Gene expression profiling induced by histone deacetylase inhibitor, FK228, in human esophageal squamous cancer cells.
    Hoshino I; Matsubara H; Akutsu Y; Nishimori T; Yoneyama Y; Murakami K; Komatsu A; Sakata H; Matsushita K; Ochiai T
    Oncol Rep; 2007 Sep; 18(3):585-92. PubMed ID: 17671705
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 4.