189 related articles for article (PubMed ID: 1627140)
1. N-and O-acetylation of aromatic and heterocyclic amine carcinogens by human monomorphic and polymorphic acetyltransferases expressed in COS-1 cells.
Minchin RF; Reeves PT; Teitel CH; McManus ME; Mojarrabi B; Ilett KF; Kadlubar FF
Biochem Biophys Res Commun; 1992 Jun; 185(3):839-44. PubMed ID: 1627140
[TBL] [Abstract][Full Text] [Related]
2. Metabolic activation of carcinogenic heterocyclic aromatic amines by human liver and colon.
Turesky RJ; Lang NP; Butler MA; Teitel CH; Kadlubar FF
Carcinogenesis; 1991 Oct; 12(10):1839-45. PubMed ID: 1934265
[TBL] [Abstract][Full Text] [Related]
3. Purification of hepatic polymorphic arylamine N-acetyltransferase from homozygous rapid acetylator inbred hamster: identity with polymorphic N-hydroxyarylamine-O-acetyltransferase.
Trinidad A; Hein DW; Rustan TD; Ferguson RJ; Miller LS; Bucher KD; Kirlin WG; Ogolla F; Andrews AF
Cancer Res; 1990 Dec; 50(24):7942-9. PubMed ID: 2253236
[TBL] [Abstract][Full Text] [Related]
4. Metabolic activation and deactivation of arylamine carcinogens by recombinant human NAT1 and polymorphic NAT2 acetyltransferases.
Hein DW; Doll MA; Rustan TD; Gray K; Feng Y; Ferguson RJ; Grant DM
Carcinogenesis; 1993 Aug; 14(8):1633-8. PubMed ID: 8353847
[TBL] [Abstract][Full Text] [Related]
5. Metabolic activation of N-hydroxy-2-aminofluorene and N-hydroxy-2-acetylaminofluorene by monomorphic N-acetyltransferase (NAT1) and polymorphic N-acetyltransferase (NAT2) in colon cytosols of Syrian hamsters congenic at the NAT2 locus.
Hein DW; Doll MA; Gray K; Rustan TD; Ferguson RJ
Cancer Res; 1993 Feb; 53(3):509-14. PubMed ID: 8425184
[TBL] [Abstract][Full Text] [Related]
6. Acetylator genotype-dependent metabolic activation of carcinogenic N-hydroxyarylamines by S-acetyl coenzyme A-dependent enzymes of inbred hamster tissue cytosols: relationship to arylamine N-acetyltransferase.
Hein DW; Flammang TJ; Kirlin WG; Trinidad A; Ogolla F
Carcinogenesis; 1987 Dec; 8(12):1767-74. PubMed ID: 3677303
[TBL] [Abstract][Full Text] [Related]
7. Metabolic activation of aromatic and heterocyclic N-hydroxyarylamines by wild-type and mutant recombinant human NAT1 and NAT2 acetyltransferases.
Hein DW; Rustan TD; Ferguson RJ; Doll MA; Gray K
Arch Toxicol; 1994; 68(2):129-33. PubMed ID: 8179482
[TBL] [Abstract][Full Text] [Related]
8. Identification and kinetic characterization of acetylator genotype-dependent and -independent arylamine carcinogen N-acetyltransferases in hamster bladder cytosol.
Yerokun T; Kirlin WG; Trinidad A; Ferguson RJ; Ogolla F; Andrews AF; Brady PK; Hein DW
Drug Metab Dispos; 1989; 17(3):231-7. PubMed ID: 2568902
[TBL] [Abstract][Full Text] [Related]
9. Metabolic activation of heterocyclic aromatic amines catalyzed by human arylamine N-acetyltransferase isozymes (NAT1 and NAT2) expressed in Salmonella typhimurium.
Wild D; Feser W; Michel S; Lord HL; Josephy PD
Carcinogenesis; 1995 Mar; 16(3):643-8. PubMed ID: 7697826
[TBL] [Abstract][Full Text] [Related]
10. Monomorphic and polymorphic human arylamine N-acetyltransferases: a comparison of liver isozymes and expressed products of two cloned genes.
Grant DM; Blum M; Beer M; Meyer UA
Mol Pharmacol; 1991 Feb; 39(2):184-91. PubMed ID: 1996083
[TBL] [Abstract][Full Text] [Related]
11. The S-acetyl coenzyme A-dependent metabolic activation of the carcinogen N-hydroxy-2-aminofluorene by human liver cytosol and its relationship to the aromatic amine N-acetyltransferase phenotype.
Flammang TJ; Yamazoe Y; Guengerich FP; Kadlubar FF
Carcinogenesis; 1987 Dec; 8(12):1967-70. PubMed ID: 3677322
[TBL] [Abstract][Full Text] [Related]
12. Cloning, sequencing, and recombinant expression of NAT1, NAT2, and NAT3 derived from the C3H/HeJ (rapid) and A/HeJ (slow) acetylator inbred mouse: functional characterization of the activation and deactivation of aromatic amine carcinogens.
Fretland AJ; Doll MA; Gray K; Feng Y; Hein DW
Toxicol Appl Pharmacol; 1997 Feb; 142(2):360-6. PubMed ID: 9070359
[TBL] [Abstract][Full Text] [Related]
13. The effect of the rs1799931 G857A (G286E) polymorphism on N-acetyltransferase 2-mediated carcinogen metabolism and genotoxicity differs with heterocyclic amine exposure.
Hein DW; Salazar-González RA; Doll MA; Zang Y
Arch Toxicol; 2023 Oct; 97(10):2697-2705. PubMed ID: 37592049
[TBL] [Abstract][Full Text] [Related]
14. Acetyltransferases and susceptibility to chemicals.
Hein DW; Rustan TD; Doll MA; Bucher KD; Ferguson RJ; Feng Y; Furman EJ; Gray K
Toxicol Lett; 1992 Dec; 64-65 Spec No():123-30. PubMed ID: 1471166
[TBL] [Abstract][Full Text] [Related]
15. Construction of Syrian hamster lines congenic at the polymorphic acetyltransferase locus (NAT2): acetylator genotype-dependent N- and O-acetylation of arylamine carcinogens.
Hein DW; Doll MA; Rustan TD; Gray K; Ferguson RJ; Feng Y
Toxicol Appl Pharmacol; 1994 Jan; 124(1):16-24. PubMed ID: 8291057
[TBL] [Abstract][Full Text] [Related]
16. Metabolic activation of 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine in Syrian hamsters congenic at the N-acetyltransferase 2 (NAT2) locus.
Fretland AJ; Devanaboyina US; Doll MA; Zhao S; Xiao GH; Hein DW
Toxicol Sci; 2003 Aug; 74(2):253-9. PubMed ID: 12773763
[TBL] [Abstract][Full Text] [Related]
17. Polymorphic and monomorphic expression of arylamine carcinogen N-acetyltransferase isozymes in tumor target organ cytosols of Syrian hamsters congenic at the polymorphic acetyltransferase locus.
Hein DW; Rustan TD; Bucher KD; Miller LS
J Pharmacol Exp Ther; 1991 Nov; 259(2):699-704. PubMed ID: 1941618
[TBL] [Abstract][Full Text] [Related]
18. Rodent models of the human acetylation polymorphism: comparisons of recombinant acetyltransferases.
Hein DW; Doll MA; Fretland AJ; Gray K; Deitz AC; Feng Y; Jiang W; Rustan TD; Satran SL; Wilkie TR
Mutat Res; 1997 May; 376(1-2):101-6. PubMed ID: 9202744
[TBL] [Abstract][Full Text] [Related]
19. Interindividual variation in the metabolic activation of heterocyclic amines and their N-hydroxy derivatives in primary cultures of human mammary epithelial cells.
Stone EM; Williams JA; Grover PL; Gusterson BA; Phillips DH
Carcinogenesis; 1998 May; 19(5):873-9. PubMed ID: 9635877
[TBL] [Abstract][Full Text] [Related]
20. Properties of cutaneous acetyltransferase catalyzing N- and O-acetylation of carcinogenic arylamines and N-hydroxyarylamine.
Kawakubo Y; Manabe S; Yamazoe Y; Nishikawa T; Kato R
Biochem Pharmacol; 1988 Jan; 37(2):265-70. PubMed ID: 3342083
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]