212 related articles for article (PubMed ID: 16274290)
1. Functional dissection of the HNF-1alpha transcription factor: a study on nuclear localization and transcriptional activation.
Bjørkhaug L; Bratland A; Njølstad PR; Molven A
DNA Cell Biol; 2005 Nov; 24(11):661-9. PubMed ID: 16274290
[TBL] [Abstract][Full Text] [Related]
2. Mutation P291fsinsC in the transcription factor hepatocyte nuclear factor-1alpha is dominant negative.
Yamagata K; Yang Q; Yamamoto K; Iwahashi H; Miyagawa J; Okita K; Yoshiuchi I; Miyazaki J; Noguchi T; Nakajima H; Namba M; Hanafusa T; Matsuzawa Y
Diabetes; 1998 Aug; 47(8):1231-5. PubMed ID: 9703322
[TBL] [Abstract][Full Text] [Related]
3. MODY associated with two novel hepatocyte nuclear factor-1alpha loss-of-function mutations (P112L and Q466X).
Bjørkhaug L; Ye H; Horikawa Y; Søvik O; Molven A; Njølstad PR
Biochem Biophys Res Commun; 2000 Dec; 279(3):792-8. PubMed ID: 11162430
[TBL] [Abstract][Full Text] [Related]
4. Functional defect of truncated hepatocyte nuclear factor-1alpha (G554fsX556) associated with maturity-onset diabetes of the young.
Kooptiwut S; Sujjitjoon J; Plengvidhya N; Boonyasrisawat W; Chongjaroen N; Jungtrakoon P; Semprasert N; Furuta H; Nanjo K; Banchuin N; Yenchitsomanus PT
Biochem Biophys Res Commun; 2009 May; 383(1):68-72. PubMed ID: 19336222
[TBL] [Abstract][Full Text] [Related]
5. Human insulin gene is a target gene of hepatocyte nuclear factor-1alpha (HNF-1alpha) and HNF-1beta.
Okita K; Yang Q; Yamagata K; Hangenfeldt KA; Miyagawa J; Kajimoto Y; Nakajima H; Namba M; Wollheim CB; Hanafusa T; Matsuzawa Y
Biochem Biophys Res Commun; 1999 Sep; 263(2):566-9. PubMed ID: 10491332
[TBL] [Abstract][Full Text] [Related]
6. Structure/function studies of hepatocyte nuclear factor-1alpha, a diabetes-associated transcription factor.
Yang Q; Yamagata K; Yamamoto K; Miyagawa J; Takeda J; Iwasaki N; Iwahashi H; Yoshiuchi I; Namba M; Miyazaki J; Hanafusa T; Matsuzawa Y
Biochem Biophys Res Commun; 1999 Dec; 266(1):196-202. PubMed ID: 10581189
[TBL] [Abstract][Full Text] [Related]
7. Mutant HNF-1alpha and mutant HNF-1beta identified in MODY3 and MODY5 downregulate DPP-IV gene expression in Caco-2 cells.
Gu N; Adachi T; Matsunaga T; Takeda J; Tsujimoto G; Ishihara A; Yasuda K; Tsuda K
Biochem Biophys Res Commun; 2006 Aug; 346(3):1016-23. PubMed ID: 16781669
[TBL] [Abstract][Full Text] [Related]
8. Analysis of a non-functional HNF-1alpha (TCF1) mutation in Japanese subjects with familial type 1 diabetes.
Yoshiuchi I; Yamagata K; Yoshimoto M; Zhu Q; Yang Q; Nammo T; Uenaka R; Kinoshita E; Hanafusa T; Miyagawa Ji ; Matsuzawa Y
Hum Mutat; 2001 Oct; 18(4):345-51. PubMed ID: 11668618
[TBL] [Abstract][Full Text] [Related]
9. Differential effects of HNF-1α mutations associated with familial young-onset diabetes on target gene regulation.
Galán M; García-Herrero CM; Azriel S; Gargallo M; Durán M; Gorgojo JJ; Andía VM; Navas MA
Mol Med; 2011; 17(3-4):256-65. PubMed ID: 21170474
[TBL] [Abstract][Full Text] [Related]
10. Mechanisms of mutual functional interactions between HNF-4alpha and HNF-1alpha revealed by mutations that cause maturity onset diabetes of the young.
Rowley CW; Staloch LJ; Divine JK; McCaul SP; Simon TC
Am J Physiol Gastrointest Liver Physiol; 2006 Mar; 290(3):G466-75. PubMed ID: 16223942
[TBL] [Abstract][Full Text] [Related]
11. Identification of seven novel nucleotide variants in the hepatocyte nuclear factor-1alpha (TCF1) promoter region in MODY patients.
Godart F; Bellanné-Chantelot C; Clauin S; Gragnoli C; Abderrahmani A; Blanché H; Boutin P; Chèvre JC; Froguel P; Bailleul B
Hum Mutat; 2000; 15(2):173-80. PubMed ID: 10649494
[TBL] [Abstract][Full Text] [Related]
12. The dimerization domain of HNF-1alpha: structure and plasticity of an intertwined four-helix bundle with application to diabetes mellitus.
Narayana N; Hua Q; Weiss MA
J Mol Biol; 2001 Jul; 310(3):635-58. PubMed ID: 11439029
[TBL] [Abstract][Full Text] [Related]
13. Effect of mutations in HNF-1alpha and HNF-1beta on the transcriptional regulation of human sucrase-isomaltase in Caco-2 cells.
Gu N; Suzuki N; Takeda J; Adachi T; Tsujimoto G; Aoki N; Ishihara A; Tsuda K; Yasuda K
Biochem Biophys Res Commun; 2004 Dec; 325(1):308-13. PubMed ID: 15522234
[TBL] [Abstract][Full Text] [Related]
14. Cloning and characterization of the human beta2-glycoprotein I (beta2-GPI) gene promoter: roles of the atypical TATA box and hepatic nuclear factor-1alpha in regulating beta2-GPI promoter activity.
Wang HH; Chiang AN
Biochem J; 2004 Jun; 380(Pt 2):455-63. PubMed ID: 14984368
[TBL] [Abstract][Full Text] [Related]
15. Regulation of human insulin, IGF-I, and multidrug resistance protein 2 promoter activity by hepatocyte nuclear factor (HNF)-1beta and HNF-1alpha and the abnormality of HNF-1beta mutants.
Kitanaka S; Sato U; Igarashi T
J Endocrinol; 2007 Jan; 192(1):141-7. PubMed ID: 17210751
[TBL] [Abstract][Full Text] [Related]
16. Structural basis of dimerization, coactivator recognition and MODY3 mutations in HNF-1alpha.
Rose RB; Bayle JH; Endrizzi JA; Cronk JD; Crabtree GR; Alber T
Nat Struct Biol; 2000 Sep; 7(9):744-8. PubMed ID: 10966642
[TBL] [Abstract][Full Text] [Related]
17. Evidence for haploinsufficiency of the human HNF1alpha gene revealed by functional characterization of MODY3-associated mutations.
Thomas H; Badenberg B; Bulman M; Lemm I; Lausen J; Kind L; Roosen S; Ellard S; Hattersley AT; Ryffel GU
Biol Chem; 2002 Nov; 383(11):1691-700. PubMed ID: 12530534
[TBL] [Abstract][Full Text] [Related]
18. Identification of three new mutations of the HNF-1 alpha gene in Japanese MODY families.
Ikema T; Shimajiri Y; Komiya I; Tawata M; Sunakawa S; Yogi H; Shimabukuro M; Takasu N
Diabetologia; 2002 Dec; 45(12):1713-8. PubMed ID: 12488962
[TBL] [Abstract][Full Text] [Related]
19. High-resolution structure of the HNF-1alpha dimerization domain.
Rose RB; Endrizzi JA; Cronk JD; Holton J; Alber T
Biochemistry; 2000 Dec; 39(49):15062-70. PubMed ID: 11106484
[TBL] [Abstract][Full Text] [Related]
20. The activity of the activation function 2 of the human hepatocyte nuclear factor 4 (HNF-4alpha) is differently modulated by F domains from various origins.
Suaud L; Formstecher P; Laine B
Biochem J; 1999 May; 340 ( Pt 1)(Pt 1):161-9. PubMed ID: 10229671
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]