BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

324 related articles for article (PubMed ID: 16280358)

  • 1. Granule-mediated killing by granzyme B and perforin requires a mannose 6-phosphate receptor and is augmented by cell surface heparan sulfate.
    Veugelers K; Motyka B; Goping IS; Shostak I; Sawchuk T; Bleackley RC
    Mol Biol Cell; 2006 Feb; 17(2):623-33. PubMed ID: 16280358
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Serglycin-deficient cytotoxic T lymphocytes display defective secretory granule maturation and granzyme B storage.
    Grujic M; Braga T; Lukinius A; Eloranta ML; Knight SD; Pejler G; Abrink M
    J Biol Chem; 2005 Sep; 280(39):33411-8. PubMed ID: 16046402
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A clathrin/dynamin- and mannose-6-phosphate receptor-independent pathway for granzyme B-induced cell death.
    Trapani JA; Sutton VR; Thia KY; Li YQ; Froelich CJ; Jans DA; Sandrin MS; Browne KA
    J Cell Biol; 2003 Jan; 160(2):223-33. PubMed ID: 12538642
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Apoptosis induced by granzyme B-glycosaminoglycan complexes: implications for granule-mediated apoptosis in vivo.
    Galvin JP; Spaeny-Dekking LH; Wang B; Seth P; Hack CE; Froelich CJ
    J Immunol; 1999 May; 162(9):5345-50. PubMed ID: 10228010
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Serglycin determines secretory granule repertoire and regulates natural killer cell and cytotoxic T lymphocyte cytotoxicity.
    Sutton VR; Brennan AJ; Ellis S; Danne J; Thia K; Jenkins MR; Voskoboinik I; Pejler G; Johnstone RW; Andrews DM; Trapani JA
    FEBS J; 2016 Mar; 283(5):947-61. PubMed ID: 26756195
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Entry and trafficking of granzyme B in target cells during granzyme B-perforin-mediated apoptosis.
    Pinkoski MJ; Hobman M; Heibein JA; Tomaselli K; Li F; Seth P; Froelich CJ; Bleackley RC
    Blood; 1998 Aug; 92(3):1044-54. PubMed ID: 9680374
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The granzyme B-serglycin complex from cytotoxic granules requires dynamin for endocytosis.
    Veugelers K; Motyka B; Frantz C; Shostak I; Sawchuk T; Bleackley RC
    Blood; 2004 May; 103(10):3845-53. PubMed ID: 14739229
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Killing by cytotoxic T cells and natural killer cells: multiple granule serine proteases as initiators of DNA fragmentation.
    Trapani JA; Smyth MJ
    Immunol Cell Biol; 1993 Jun; 71 ( Pt 3)():201-8. PubMed ID: 8349302
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cytotoxic granule-mediated apoptosis: unraveling the complex mechanism.
    Raja SM; Metkar SS; Froelich CJ
    Curr Opin Immunol; 2003 Oct; 15(5):528-32. PubMed ID: 14499261
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Interaction of chondroitin sulfate with perforin and granzymes of cytolytic T-cells is dependent on pH.
    Masson D; Peters PJ; Geuze HJ; Borst J; Tschopp J
    Biochemistry; 1990 Dec; 29(51):11229-35. PubMed ID: 2125503
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Cytotoxic cell granule-mediated apoptosis: perforin delivers granzyme B-serglycin complexes into target cells without plasma membrane pore formation.
    Metkar SS; Wang B; Aguilar-Santelises M; Raja SM; Uhlin-Hansen L; Podack E; Trapani JA; Froelich CJ
    Immunity; 2002 Mar; 16(3):417-28. PubMed ID: 11911826
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Cytotoxic T lymphocyte granules are secretory lysosomes, containing both perforin and granzymes.
    Peters PJ; Borst J; Oorschot V; Fukuda M; Krähenbühl O; Tschopp J; Slot JW; Geuze HJ
    J Exp Med; 1991 May; 173(5):1099-109. PubMed ID: 2022921
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Serial killing by cytotoxic T lymphocytes: T cell receptor triggers degranulation, re-filling of the lytic granules and secretion of lytic proteins via a non-granule pathway.
    Isaaz S; Baetz K; Olsen K; Podack E; Griffiths GM
    Eur J Immunol; 1995 Apr; 25(4):1071-9. PubMed ID: 7737276
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Granzyme-mediated cytotoxicity does not involve the mannose 6-phosphate receptors on target cells.
    Dressel R; Raja SM; Höning S; Seidler T; Froelich CJ; von Figura K; Günther E
    J Biol Chem; 2004 May; 279(19):20200-10. PubMed ID: 14985351
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Cytosolic delivery of granzyme B by bacterial toxins: evidence that endosomal disruption, in addition to transmembrane pore formation, is an important function of perforin.
    Browne KA; Blink E; Sutton VR; Froelich CJ; Jans DA; Trapani JA
    Mol Cell Biol; 1999 Dec; 19(12):8604-15. PubMed ID: 10567584
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Cutting edge: granzymes A and B are not essential for perforin-mediated tumor rejection.
    Smyth MJ; Street SE; Trapani JA
    J Immunol; 2003 Jul; 171(2):515-8. PubMed ID: 12847210
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Target cell apoptosis induced by cytotoxic T cells and natural killer cells involves synergy between the pore-forming protein, perforin, and the serine protease, granzyme B.
    Trapani JA
    Aust N Z J Med; 1995 Dec; 25(6):793-9. PubMed ID: 8770355
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mannose 6-phosphate/insulin-like growth factor II receptor is a death receptor for granzyme B during cytotoxic T cell-induced apoptosis.
    Motyka B; Korbutt G; Pinkoski MJ; Heibein JA; Caputo A; Hobman M; Barry M; Shostak I; Sawchuk T; Holmes CF; Gauldie J; Bleackley RC
    Cell; 2000 Oct; 103(3):491-500. PubMed ID: 11081635
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A novel mechanism for protein delivery: granzyme B undergoes electrostatic exchange from serglycin to target cells.
    Raja SM; Metkar SS; Höning S; Wang B; Russin WA; Pipalia NH; Menaa C; Belting M; Cao X; Dressel R; Froelich CJ
    J Biol Chem; 2005 May; 280(21):20752-61. PubMed ID: 15788411
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Granzyme B induces smooth muscle cell apoptosis in the absence of perforin: involvement of extracellular matrix degradation.
    Choy JC; Hung VH; Hunter AL; Cheung PK; Motyka B; Goping IS; Sawchuk T; Bleackley RC; Podor TJ; McManus BM; Granville DJ
    Arterioscler Thromb Vasc Biol; 2004 Dec; 24(12):2245-50. PubMed ID: 15472125
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.