BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

258 related articles for article (PubMed ID: 16280588)

  • 1. Silencing primary dystonia: lentiviral-mediated RNA interference therapy for DYT1 dystonia.
    Gonzalez-Alegre P; Bode N; Davidson BL; Paulson HL
    J Neurosci; 2005 Nov; 25(45):10502-9. PubMed ID: 16280588
    [TBL] [Abstract][Full Text] [Related]  

  • 2. siRNA knock-down of mutant torsinA restores processing through secretory pathway in DYT1 dystonia cells.
    Hewett JW; Nery FC; Niland B; Ge P; Tan P; Hadwiger P; Tannous BA; Sah DW; Breakefield XO
    Hum Mol Genet; 2008 May; 17(10):1436-45. PubMed ID: 18258738
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Dystonia-associated protein torsinA is not detectable at the nerve terminals of central neurons.
    Koh JY; Iwabuchi S; Harata NC
    Neuroscience; 2013 Dec; 253():316-29. PubMed ID: 24025868
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Aberrant cellular behavior of mutant torsinA implicates nuclear envelope dysfunction in DYT1 dystonia.
    Gonzalez-Alegre P; Paulson HL
    J Neurosci; 2004 Mar; 24(11):2593-601. PubMed ID: 15028751
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Consequences of the DYT1 mutation on torsinA oligomerization and degradation.
    Gordon KL; Gonzalez-Alegre P
    Neuroscience; 2008 Dec; 157(3):588-95. PubMed ID: 18940237
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The nuclear envelope localization of DYT1 dystonia torsinA-ΔE requires the SUN1 LINC complex component.
    Jungwirth MT; Kumar D; Jeong DY; Goodchild RE
    BMC Cell Biol; 2011 May; 12():24. PubMed ID: 21627841
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Toward therapy for DYT1 dystonia: allele-specific silencing of mutant TorsinA.
    Gonzalez-Alegre P; Miller VM; Davidson BL; Paulson HL
    Ann Neurol; 2003 Jun; 53(6):781-7. PubMed ID: 12783425
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Efficient RNA interference-based knockdown of mutant torsinA reveals reversibility of PERK-eIF2α pathway dysregulation in DYT1 transgenic rats in vivo.
    Beauvais G; Watson JL; Aguirre JA; Tecedor L; Ehrlich ME; Gonzalez-Alegre P
    Brain Res; 2019 Mar; 1706():24-31. PubMed ID: 30366018
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A novel conditional knock-in approach defines molecular and circuit effects of the DYT1 dystonia mutation.
    Weisheit CE; Dauer WT
    Hum Mol Genet; 2015 Nov; 24(22):6459-72. PubMed ID: 26370418
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Chemical enhancement of torsinA function in cell and animal models of torsion dystonia.
    Cao S; Hewett JW; Yokoi F; Lu J; Buckley AC; Burdette AJ; Chen P; Nery FC; Li Y; Breakefield XO; Caldwell GA; Caldwell KA
    Dis Model Mech; 2010; 3(5-6):386-96. PubMed ID: 20223934
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Transcriptional and proteomic profiling in a cellular model of DYT1 dystonia.
    Martin JN; Bair TB; Bode N; Dauer WT; Gonzalez-Alegre P
    Neuroscience; 2009 Dec; 164(2):563-72. PubMed ID: 19665049
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synaptic vesicle recycling is enhanced by torsinA that harbors the DYT1 dystonia mutation.
    Kakazu Y; Koh JY; Ho KW; Gonzalez-Alegre P; Harata NC
    Synapse; 2012 May; 66(5):453-64. PubMed ID: 22213465
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structure of the Golgi apparatus is not influenced by a GAG deletion mutation in the dystonia-associated gene Tor1a.
    Mitchell SB; Iwabuchi S; Kawano H; Yuen TMT; Koh JY; Ho KWD; Harata NC
    PLoS One; 2018; 13(11):e0206123. PubMed ID: 30403723
    [TBL] [Abstract][Full Text] [Related]  

  • 14. RNAi blocks DYT1 mutant torsinA inclusions in neurons.
    Kock N; Allchorne AJ; Sena-Esteves M; Woolf CJ; Breakefield XO
    Neurosci Lett; 2006 Mar; 395(3):201-5. PubMed ID: 16332410
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The zebrafish homologue of the human DYT1 dystonia gene is widely expressed in CNS neurons but non-essential for early motor system development.
    Sager JJ; Torres GE; Burton EA
    PLoS One; 2012; 7(9):e45175. PubMed ID: 23028827
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The ubiquitin ligase F-box/G-domain protein 1 promotes the degradation of the disease-linked protein torsinA through the ubiquitin-proteasome pathway and macroautophagy.
    Gordon KL; Glenn KA; Bode N; Wen HM; Paulson HL; Gonzalez-Alegre P
    Neuroscience; 2012 Nov; 224():160-71. PubMed ID: 22917612
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Disruption of Protein Processing in the Endoplasmic Reticulum of DYT1 Knock-in Mice Implicates Novel Pathways in Dystonia Pathogenesis.
    Beauvais G; Bode NM; Watson JL; Wen H; Glenn KA; Kawano H; Harata NC; Ehrlich ME; Gonzalez-Alegre P
    J Neurosci; 2016 Oct; 36(40):10245-10256. PubMed ID: 27707963
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Pre-synaptic release deficits in a DYT1 dystonia mouse model.
    Yokoi F; Cheetham CC; Campbell SL; Sweatt JD; Li Y
    PLoS One; 2013; 8(8):e72491. PubMed ID: 23967309
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cerebellothalamocortical pathway abnormalities in torsinA DYT1 knock-in mice.
    Uluğ AM; Vo A; Argyelan M; Tanabe L; Schiffer WK; Dewey S; Dauer WT; Eidelberg D
    Proc Natl Acad Sci U S A; 2011 Apr; 108(16):6638-43. PubMed ID: 21464304
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Characterization of the porcine TOR1A gene: The first step towards generation of a pig model for dystonia.
    Henriksen C; Madsen LB; Bendixen C; Larsen K
    Gene; 2009 Feb; 430(1-2):105-15. PubMed ID: 19028553
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.