BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

204 related articles for article (PubMed ID: 16284303)

  • 1. Mechanism of action of a novel human ether-a-go-go-related gene channel activator.
    Casis O; Olesen SP; Sanguinetti MC
    Mol Pharmacol; 2006 Feb; 69(2):658-65. PubMed ID: 16284303
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Activation of human ether-a-go-go-related gene potassium channels by the diphenylurea 1,3-bis-(2-hydroxy-5-trifluoromethyl-phenyl)-urea (NS1643).
    Hansen RS; Diness TG; Christ T; Demnitz J; Ravens U; Olesen SP; Grunnet M
    Mol Pharmacol; 2006 Jan; 69(1):266-77. PubMed ID: 16219910
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Strong activation of ether-à-go-go-related gene 1 K+ channel isoforms by NS1643 in human embryonic kidney 293 and Chinese hamster ovary cells.
    Schuster AM; Glassmeier G; Bauer CK
    Mol Pharmacol; 2011 Nov; 80(5):930-42. PubMed ID: 21856740
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Potent activation of large-conductance Ca2+-activated K+ channels by the diphenylurea 1,3-bis-[2-hydroxy-5-(trifluoromethyl)phenyl]urea (NS1643) in pituitary tumor (GH3) cells.
    Wu SN; Peng H; Chen BS; Wang YJ; Wu PY; Lin MW
    Mol Pharmacol; 2008 Dec; 74(6):1696-704. PubMed ID: 18809671
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Probing the binding sites and mechanisms of action of two human ether-a-go-go-related gene channel activators, 1,3-bis-(2-hydroxy-5-trifluoromethyl-phenyl)-urea (NS1643) and 2-[2-(3,4-dichloro-phenyl)-2,3-dihydro-1H-isoindol-5-ylamino]-nicotinic acid (PD307243).
    Xu X; Recanatini M; Roberti M; Tseng GN
    Mol Pharmacol; 2008 Jun; 73(6):1709-21. PubMed ID: 18372399
    [TBL] [Abstract][Full Text] [Related]  

  • 6. NS1643 enhances ionic currents in a G604S-WT hERG co-expression system associated with long QT syndrome 2.
    Huo J; Guo X; Lu Q; Qiang H; Liu P; Bai L; Huang CL; Zhang Y; Ma A
    Clin Exp Pharmacol Physiol; 2017 Nov; 44(11):1125-1133. PubMed ID: 28741726
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Block of wild-type and inactivation-deficient human ether-a-go-go-related gene K+ channels by halofantrine.
    Sánchez-Chapula JA; Navarro-Polanco RA; Sanguinetti MC
    Naunyn Schmiedebergs Arch Pharmacol; 2004 Dec; 370(6):484-91. PubMed ID: 15558243
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Molecular determinants of human ether-à-go-go-related gene 1 (hERG1) K+ channel activation by NS1643.
    Grunnet M; Abbruzzese J; Sachse FB; Sanguinetti MC
    Mol Pharmacol; 2011 Jan; 79(1):1-9. PubMed ID: 20876384
    [TBL] [Abstract][Full Text] [Related]  

  • 9. NS1643 interacts around L529 of hERG to alter voltage sensor movement on the path to activation.
    Guo J; Cheng YM; Lees-Miller JP; Perissinotti LL; Claydon TW; Hull CM; Thouta S; Roach DE; Durdagi S; Noskov SY; Duff HJ
    Biophys J; 2015 Mar; 108(6):1400-1413. PubMed ID: 25809253
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The human ether-a-go-go-related gene activator NS1643 enhances epilepsy-associated KCNQ channels.
    Li P; Chen X; Zhang Q; Zheng Y; Jiang H; Yang H; Gao Z
    J Pharmacol Exp Ther; 2014 Dec; 351(3):596-604. PubMed ID: 25232191
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structure-guided topographic mapping and mutagenesis to elucidate binding sites for the human ether-a-go-go-related gene 1 potassium channel (KCNH2) activator NS1643.
    Durdagi S; Guo J; Lees-Miller JP; Noskov SY; Duff HJ
    J Pharmacol Exp Ther; 2012 Aug; 342(2):441-52. PubMed ID: 22573844
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A mutation in the pore region of HERG K+ channels expressed in Xenopus oocytes reduces rectification by shifting the voltage dependence of inactivation.
    Zou A; Xu QP; Sanguinetti MC
    J Physiol; 1998 May; 509 ( Pt 1)(Pt 1):129-37. PubMed ID: 9547387
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Differential effects of Kv11.1 activators on Kv11.1a, Kv11.1b and Kv11.1a/Kv11.1b channels.
    Larsen AP; Bentzen BH; Grunnet M
    Br J Pharmacol; 2010 Oct; 161(3):614-28. PubMed ID: 20880400
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Altered gating of HERG potassium channels by cobalt and lanthanum.
    Sanchez-Chapula JA; Sanguinetti MC
    Pflugers Arch; 2000 Jun; 440(2):264-74. PubMed ID: 10898527
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Activation of ERG2 potassium channels by the diphenylurea NS1643.
    Elmedyb P; Olesen SP; Grunnet M
    Neuropharmacology; 2007 Aug; 53(2):283-94. PubMed ID: 17610913
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Effects of the small molecule HERG activator NS1643 on Kv11.3 channels.
    Bilet A; Bauer CK
    PLoS One; 2012; 7(11):e50886. PubMed ID: 23226420
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Blockade of the human ether-a-go-go-related gene potassium channel by ketanserin.
    Tu DN; Zou AR; Liao YH; Du YM; Wang XP; Li L
    Sheng Li Xue Bao; 2008 Aug; 60(4):525-34. PubMed ID: 18690396
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The inhibitory effect of the antipsychotic drug haloperidol on HERG potassium channels expressed in Xenopus oocytes.
    Suessbrich H; Schönherr R; Heinemann SH; Attali B; Lang F; Busch AE
    Br J Pharmacol; 1997 Mar; 120(5):968-74. PubMed ID: 9138706
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Biophysical characterization of the new human ether-a-go-go-related gene channel opener NS3623 [N-(4-bromo-2-(1H-tetrazol-5-yl)-phenyl)-N'-(3'-trifluoromethylphenyl)urea].
    Hansen RS; Diness TG; Christ T; Wettwer E; Ravens U; Olesen SP; Grunnet M
    Mol Pharmacol; 2006 Oct; 70(4):1319-29. PubMed ID: 16825484
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Enhancement of HERG K+ currents by Cd2+ destabilization of the inactivated state.
    Johnson JP; Balser JR; Bennett PB
    Biophys J; 1999 Nov; 77(5):2534-41. PubMed ID: 10545354
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.