BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

140 related articles for article (PubMed ID: 16289482)

  • 1. Synthesis and evaluation of 7-amino-2-(2(3)-furyl)-5-phenylethylamino-oxazolo[5,4-d]pyrimidines as potential A2A adenosine receptor antagonists for positron emission tomography (PET).
    Holschbach MH; Bier D; Stüsgen S; Wutz W; Sihver W; Coenen HH; Olsson RA
    Eur J Med Chem; 2006 Jan; 41(1):7-15. PubMed ID: 16289482
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Derivatives of 4,6-diamino-1,2-dihydro-2-phenyl-1,2,4-triazolo[4,3-a]quinoxalin-2H-1-one: potential antagonist ligands for imaging the A2A adenosine receptor by positron emission tomography (PET).
    Holschbach MH; Bier D; Wutz W; Sihver W; Schüller M; Olsson RA
    Eur J Med Chem; 2005 May; 40(5):421-37. PubMed ID: 15893016
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Chiral pyrrolo[2,3-d]pyrimidine and pyrimido[4,5-b]indole derivatives: structure-activity relationships of potent, highly stereoselective A1-adenosine receptor antagonists.
    Müller CE; Geis U; Grahner B; Lanzner W; Eger K
    J Med Chem; 1996 Jun; 39(13):2482-91. PubMed ID: 8691445
    [TBL] [Abstract][Full Text] [Related]  

  • 4. 7-Substituted 5-amino-2-(2-furyl)pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidines as A2A adenosine receptor antagonists: a study on the importance of modifications at the side chain on the activity and solubility.
    Baraldi PG; Cacciari B; Romagnoli R; Spalluto G; Monopoli A; Ongini E; Varani K; Borea PA
    J Med Chem; 2002 Jan; 45(1):115-26. PubMed ID: 11754583
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Design, synthesis, and biological evaluation of C9- and C2-substituted pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidines as new A2A and A3 adenosine receptors antagonists.
    Baraldi PG; Fruttarolo F; Tabrizi MA; Preti D; Romagnoli R; El-Kashef H; Moorman A; Varani K; Gessi S; Merighi S; Borea PA
    J Med Chem; 2003 Mar; 46(7):1229-41. PubMed ID: 12646033
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Autoradiographic comparison of in vitro binding characteristics of various tritiated adenosine A2A receptor ligands in rat, mouse and pig brain and first ex vivo results.
    Sihver W; Schulze A; Wutz W; Stüsgen S; Olsson RA; Bier D; Holschbach MH
    Eur J Pharmacol; 2009 Aug; 616(1-3):107-14. PubMed ID: 19545560
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Development of [18F]-labeled pyrazolo[4,3-e]-1,2,4- triazolo[1,5-c]pyrimidine (SCH442416) analogs for the imaging of cerebral adenosine A2A receptors with positron emission tomography.
    Khanapur S; Paul S; Shah A; Vatakuti S; Koole MJ; Zijlma R; Dierckx RA; Luurtsema G; Garg P; van Waarde A; Elsinga PH
    J Med Chem; 2014 Aug; 57(15):6765-80. PubMed ID: 25061687
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The role of 5-arylalkylamino- and 5-piperazino- moieties on the 7-aminopyrazolo[4,3-d]pyrimidine core in affecting adenosine A
    Squarcialupi L; Betti M; Catarzi D; Varano F; Falsini M; Ravani A; Pasquini S; Vincenzi F; Salmaso V; Sturlese M; Varani K; Moro S; Colotta V
    J Enzyme Inhib Med Chem; 2017 Dec; 32(1):248-263. PubMed ID: 28114825
    [TBL] [Abstract][Full Text] [Related]  

  • 9. 7-Amino-2-phenylpyrazolo[4,3-d]pyrimidine derivatives: structural investigations at the 5-position to target human A₁ and A(2A) adenosine receptors. Molecular modeling and pharmacological studies.
    Squarcialupi L; Colotta V; Catarzi D; Varano F; Betti M; Varani K; Vincenzi F; Borea PA; Porta N; Ciancetta A; Moro S
    Eur J Med Chem; 2014 Sep; 84():614-27. PubMed ID: 25063944
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Replacement of amide with bioisosteres led to a new series of potent adenosine A2A receptor antagonists.
    Yang Z; Li X; Ma H; Zheng J; Zhen X; Zhang X
    Bioorg Med Chem Lett; 2014 Jan; 24(1):152-5. PubMed ID: 24332624
    [TBL] [Abstract][Full Text] [Related]  

  • 11. 2,4,6-trisubstituted pyrimidines as a new class of selective adenosine A1 receptor antagonists.
    Chang LC; Spanjersberg RF; von Frijtag Drabbe Künzel JK; Mulder-Krieger T; van den Hout G; Beukers MW; Brussee J; Ijzerman AP
    J Med Chem; 2004 Dec; 47(26):6529-40. PubMed ID: 15588088
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Development of
    Lai TH; Schröder S; Toussaint M; Dukić-Stefanović S; Kranz M; Ludwig FA; Fischer S; Steinbach J; Deuther-Conrad W; Brust P; Moldovan RP
    Int J Mol Sci; 2021 Feb; 22(5):. PubMed ID: 33669003
    [TBL] [Abstract][Full Text] [Related]  

  • 13. JNJ-40255293, a novel adenosine A2A/A1 antagonist with efficacy in preclinical models of Parkinson's disease.
    Atack JR; Shook BC; Rassnick S; Jackson PF; Rhodes K; Drinkenburg WH; Ahnaou A; Te Riele P; Langlois X; Hrupka B; De Haes P; Hendrickx H; Aerts N; Hens K; Wellens A; Vermeire J; Megens AA
    ACS Chem Neurosci; 2014 Oct; 5(10):1005-19. PubMed ID: 25203719
    [TBL] [Abstract][Full Text] [Related]  

  • 14. 2-Aminopyrimidines as dual adenosine A1/A2A antagonists.
    Robinson SJ; Petzer JP; Terre'Blanche G; Petzer A; van der Walt MM; Bergh JJ; Lourens AC
    Eur J Med Chem; 2015 Nov; 104():177-88. PubMed ID: 26462195
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Allosteric Antagonism of the A
    Gao ZG; Toti KS; Campbell R; Suresh RR; Yang H; Jacobson KA
    Cells; 2020 May; 9(5):. PubMed ID: 32408534
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The significance of 2-furyl ring substitution with a 2-(para-substituted) aryl group in a new series of pyrazolo-triazolo-pyrimidines as potent and highly selective hA(3) adenosine receptors antagonists: new insights into structure-affinity relationship and receptor-antagonist recognition.
    Cheong SL; Dolzhenko A; Kachler S; Paoletta S; Federico S; Cacciari B; Dolzhenko A; Klotz KN; Moro S; Spalluto G; Pastorin G
    J Med Chem; 2010 Apr; 53(8):3361-75. PubMed ID: 20307065
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis and in vivo Evaluation of Fluorine-18 and Iodine-123 Pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidine Derivatives as PET and SPECT Radiotracers for Mapping A2A Receptors.
    Vala C; Morley TJ; Zhang X; Papin C; Tavares AA; Lee HS; Constantinescu C; Barret O; Carroll VM; Baldwin RM; Tamagnan GD; Alagille D
    ChemMedChem; 2016 Sep; 11(17):1936-43. PubMed ID: 27407017
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Potential Therapeutic Applications of Adenosine A
    van Waarde A; Dierckx RAJO; Zhou X; Khanapur S; Tsukada H; Ishiwata K; Luurtsema G; de Vries EFJ; Elsinga PH
    Med Res Rev; 2018 Jan; 38(1):5-56. PubMed ID: 28128443
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Discovery of 7-(Prolinol-N-yl)-2-phenylamino-thiazolo[5,4-d]pyrimidines as Novel Non-Nucleoside Partial Agonists for the A2A Adenosine Receptor: Prediction from Molecular Modeling.
    Bharate SB; Singh B; Kachler S; Oliveira A; Kumar V; Bharate SS; Vishwakarma RA; Klotz KN; Gutiérrez de Terán H
    J Med Chem; 2016 Jun; 59(12):5922-8. PubMed ID: 27227326
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Design, synthesis and biological evaluation of Tozadenant analogues as adenosine A
    Renk DR; Skraban M; Bier D; Schulze A; Wabbals E; Wedekind F; Neumaier F; Neumaier B; Holschbach M
    Eur J Med Chem; 2021 Mar; 214():113214. PubMed ID: 33548636
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.