251 related articles for article (PubMed ID: 16292827)
1. Synthesis and evaluation of 1-deoxy-D-xylulose 5-phosphate analogues as chelation-based inhibitors of methylerythritol phosphate synthase.
Walker JR; Poulter CD
J Org Chem; 2005 Nov; 70(24):9955-9. PubMed ID: 16292827
[TBL] [Abstract][Full Text] [Related]
2. Synthesis and evaluation of 1-deoxy-D-xylulose 5-phosphoric acid analogues as alternate substrates for methylerythritol phosphate synthase.
Fox DT; Poulter CD
J Org Chem; 2005 Mar; 70(6):1978-85. PubMed ID: 15760175
[TBL] [Abstract][Full Text] [Related]
3. Isoprenoid biosynthesis via the methylerythritol phosphate pathway: structural variations around phosphonate anchor and spacer of fosmidomycin, a potent inhibitor of deoxyxylulose phosphate reductoisomerase.
Zinglé C; Kuntz L; Tritsch D; Grosdemange-Billiard C; Rohmer M
J Org Chem; 2010 May; 75(10):3203-7. PubMed ID: 20429517
[TBL] [Abstract][Full Text] [Related]
4. 1-Deoxy-D-xylulose 5-phosphate reductoisomerase: an overview.
Proteau PJ
Bioorg Chem; 2004 Dec; 32(6):483-93. PubMed ID: 15530989
[TBL] [Abstract][Full Text] [Related]
5. Synthesis and analysis of a fluorinated product analogue as an inhibitor for 1-deoxy-D-xylulose 5-phosphate reductoisomerase.
Munos JW; Pu X; Liu HW
Bioorg Med Chem Lett; 2008 May; 18(10):3090-4. PubMed ID: 18078746
[TBL] [Abstract][Full Text] [Related]
6. Evaluation of fosmidomycin analogs as inhibitors of the Synechocystis sp. PCC6803 1-deoxy-D-xylulose 5-phosphate reductoisomerase.
Woo YH; Fernandes RP; Proteau PJ
Bioorg Med Chem; 2006 Apr; 14(7):2375-85. PubMed ID: 16310360
[TBL] [Abstract][Full Text] [Related]
7. Study of 1-deoxy-D-xylulose-5-phosphate reductoisomerase: synthesis and evaluation of fluorinated substrate analogues.
Wong A; Munos JW; Devasthali V; Johnson KA; Liu HW
Org Lett; 2004 Sep; 6(20):3625-8. PubMed ID: 15387564
[TBL] [Abstract][Full Text] [Related]
8. Mechanistic studies with 2-C-methyl-D-erythritol 4-phosphate synthase from Escherichia coli.
Fox DT; Poulter CD
Biochemistry; 2005 Jun; 44(23):8360-8. PubMed ID: 15938625
[TBL] [Abstract][Full Text] [Related]
9. Methylerythritol phosphate pathway to isoprenoids: kinetic modeling and in silico enzyme inhibitions in Plasmodium falciparum.
Singh VK; Ghosh I
FEBS Lett; 2013 Sep; 587(17):2806-17. PubMed ID: 23816706
[TBL] [Abstract][Full Text] [Related]
10. Substrate analogs for the investigation of deoxyxylulose 5-phosphate reductoisomerase inhibition: synthesis and evaluation.
Phaosiri C; Proteau PJ
Bioorg Med Chem Lett; 2004 Nov; 14(21):5309-12. PubMed ID: 15454217
[TBL] [Abstract][Full Text] [Related]
11. Isoprenoid biosynthesis via the MEP pathway. Synthesis of (3,4)-3,4-dihydroxy-5-oxohexylphosphonic acid, an isosteric analogue of 1-deoxy-D-xylulose 5-phosphate, the substrate of the 1-deoxy-D-xylulose 5-phosphate reducto-isomerase.
Meyer O; Grosdemange-Billiard C; Tritsch D; Rohmer M
Org Biomol Chem; 2003 Dec; 1(24):4367-72. PubMed ID: 14685307
[TBL] [Abstract][Full Text] [Related]
12. Synthesis and biological evaluation of cyclopropyl analogues of fosmidomycin as potent Plasmodium falciparum growth inhibitors.
Devreux V; Wiesner J; Goeman JL; Van der Eycken J; Jomaa H; Van Calenbergh S
J Med Chem; 2006 Apr; 49(8):2656-60. PubMed ID: 16610809
[TBL] [Abstract][Full Text] [Related]
13. Towards new antimalarial drugs: synthesis of non-hydrolyzable phosphate mimics as feed for a predictive QSAR study on 1-deoxy-D-xylulose-5-phosphate reductoisomerase inhibitors.
Giessmann D; Heidler P; Haemers T; Van Calenbergh S; Reichenberg A; Jomaa H; Weidemeyer C; Sanderbrand S; Wiesner J; Link A
Chem Biodivers; 2008 Apr; 5(4):643-56. PubMed ID: 18421757
[TBL] [Abstract][Full Text] [Related]
14. Kinetic and chemical mechanism of Mycobacterium tuberculosis 1-deoxy-D-xylulose-5-phosphate isomeroreductase.
Argyrou A; Blanchard JS
Biochemistry; 2004 Apr; 43(14):4375-84. PubMed ID: 15065882
[TBL] [Abstract][Full Text] [Related]
15. A high-throughput screening assay for simultaneous selection of inhibitors of Mycobacterium tuberculosis 1-deoxy-D-xylulose-5-phosphate synthase (Dxs) or 1-deoxy-D-xylulose 5-phosphate reductoisomerase (Dxr).
Humnabadkar V; Jha RK; Ghatnekar N; De Sousa SM
J Biomol Screen; 2011 Mar; 16(3):303-12. PubMed ID: 21335601
[TBL] [Abstract][Full Text] [Related]
16. Synthesis and evaluation of alpha,beta-unsaturated alpha-aryl-substituted fosmidomycin analogues as DXR inhibitors.
Devreux V; Wiesner J; Jomaa H; Van der Eycken J; Van Calenbergh S
Bioorg Med Chem Lett; 2007 Sep; 17(17):4920-3. PubMed ID: 17583502
[TBL] [Abstract][Full Text] [Related]
17. Coordination chemistry based approach to lipophilic inhibitors of 1-deoxy-D-xylulose-5-phosphate reductoisomerase.
Deng L; Sundriyal S; Rubio V; Shi ZZ; Song Y
J Med Chem; 2009 Nov; 52(21):6539-42. PubMed ID: 19888756
[TBL] [Abstract][Full Text] [Related]
18. Novel deoxyxylulosephosphate-reductoisomerase inhibitors: fosmidomycin derivatives with spacious acyl residues.
Ortmann R; Wiesner J; Silber K; Klebe G; Jomaa H; Schlitzer M
Arch Pharm (Weinheim); 2007 Sep; 340(9):483-90. PubMed ID: 17806130
[TBL] [Abstract][Full Text] [Related]
19. Studies addressing the importance of charge in the binding of fosmidomycin-like molecules to deoxyxylulosephosphate reductoisomerase.
Perruchon J; Ortmann R; Altenkämper M; Silber K; Wiesner J; Jomaa H; Klebe G; Schlitzer M
ChemMedChem; 2008 Aug; 3(8):1232-41. PubMed ID: 18470849
[TBL] [Abstract][Full Text] [Related]
20. Mutation in the flexible loop of 1-deoxy-D-xylulose 5-phosphate reductoisomerase broadens substrate utilization.
Fernandes RP; Phaosiri C; Proteau PJ
Arch Biochem Biophys; 2005 Dec; 444(2):159-64. PubMed ID: 16289362
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
