BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

450 related articles for article (PubMed ID: 16293762)

  • 1. DISC1 and PDE4B are interacting genetic factors in schizophrenia that regulate cAMP signaling.
    Millar JK; Pickard BS; Mackie S; James R; Christie S; Buchanan SR; Malloy MP; Chubb JE; Huston E; Baillie GS; Thomson PA; Hill EV; Brandon NJ; Rain JC; Camargo LM; Whiting PJ; Houslay MD; Blackwood DH; Muir WJ; Porteous DJ
    Science; 2005 Nov; 310(5751):1187-91. PubMed ID: 16293762
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Isoform-selective susceptibility of DISC1/phosphodiesterase-4 complexes to dissociation by elevated intracellular cAMP levels.
    Murdoch H; Mackie S; Collins DM; Hill EV; Bolger GB; Klussmann E; Porteous DJ; Millar JK; Houslay MD
    J Neurosci; 2007 Aug; 27(35):9513-24. PubMed ID: 17728464
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Disrupted in schizophrenia 1 and phosphodiesterase 4B: towards an understanding of psychiatric illness.
    Millar JK; Mackie S; Clapcote SJ; Murdoch H; Pickard BS; Christie S; Muir WJ; Blackwood DH; Roder JC; Houslay MD; Porteous DJ
    J Physiol; 2007 Oct; 584(Pt 2):401-5. PubMed ID: 17823207
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Role of DISC1 in neural development and schizophrenia.
    Mackie S; Millar JK; Porteous DJ
    Curr Opin Neurobiol; 2007 Feb; 17(1):95-102. PubMed ID: 17258902
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Genetics. Two genes link two distinct psychoses.
    Sawa A; Snyder SH
    Science; 2005 Nov; 310(5751):1128-9. PubMed ID: 16293746
    [No Abstract]   [Full Text] [Related]  

  • 6. Disrupted in schizophrenia 1: building brains and memories.
    Porteous DJ; Millar JK
    Trends Mol Med; 2006 Jun; 12(6):255-61. PubMed ID: 16679065
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Disrupted-in-schizophrenia-1 (DISC1): a key susceptibility factor for major mental illnesses.
    Sawamura N; Sawa A
    Ann N Y Acad Sci; 2006 Nov; 1086():126-33. PubMed ID: 17185511
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Antipsychotic profile of rolipram: efficacy in rats and reduced sensitivity in mice deficient in the phosphodiesterase-4B (PDE4B) enzyme.
    Siuciak JA; Chapin DS; McCarthy SA; Martin AN
    Psychopharmacology (Berl); 2007 Jun; 192(3):415-24. PubMed ID: 17333137
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The PDE4B gene confers sex-specific protection against schizophrenia.
    Pickard BS; Thomson PA; Christoforou A; Evans KL; Morris SW; Porteous DJ; Blackwood DH; Muir WJ
    Psychiatr Genet; 2007 Jun; 17(3):129-33. PubMed ID: 17417055
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The phosphodiesterase PDE4B limits cAMP-associated PI3K/AKT-dependent apoptosis in diffuse large B-cell lymphoma.
    Smith PG; Wang F; Wilkinson KN; Savage KJ; Klein U; Neuberg DS; Bollag G; Shipp MA; Aguiar RC
    Blood; 2005 Jan; 105(1):308-16. PubMed ID: 15331441
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Specific Inhibition of Phosphodiesterase-4B Results in Anxiolysis and Facilitates Memory Acquisition.
    McGirr A; Lipina TV; Mun HS; Georgiou J; Al-Amri AH; Ng E; Zhai D; Elliott C; Cameron RT; Mullins JG; Liu F; Baillie GS; Clapcote SJ; Roder JC
    Neuropsychopharmacology; 2016 Mar; 41(4):1080-92. PubMed ID: 26272049
    [TBL] [Abstract][Full Text] [Related]  

  • 12. PGE(1) stimulation of HEK293 cells generates multiple contiguous domains with different [cAMP]: role of compartmentalized phosphodiesterases.
    Terrin A; Di Benedetto G; Pertegato V; Cheung YF; Baillie G; Lynch MJ; Elvassore N; Prinz A; Herberg FW; Houslay MD; Zaccolo M
    J Cell Biol; 2006 Nov; 175(3):441-51. PubMed ID: 17088426
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Selective up-regulation of phosphodiesterase-4 cyclic adenosine 3',5'-monophosphate (cAMP)-specific phosphodiesterase variants by elevated cAMP content in human myometrial cells in culture.
    Méhats C; Tanguy G; Dallot E; Robert B; Rebourcet R; Ferré F; Leroy MJ
    Endocrinology; 1999 Jul; 140(7):3228-37. PubMed ID: 10385419
    [TBL] [Abstract][Full Text] [Related]  

  • 14. PDE4B5, a novel, super-short, brain-specific cAMP phosphodiesterase-4 variant whose isoform-specifying N-terminal region is identical to that of cAMP phosphodiesterase-4D6 (PDE4D6).
    Cheung YF; Kan Z; Garrett-Engele P; Gall I; Murdoch H; Baillie GS; Camargo LM; Johnson JM; Houslay MD; Castle JC
    J Pharmacol Exp Ther; 2007 Aug; 322(2):600-9. PubMed ID: 17519386
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Regulation of cAMP-specific phosphodiesterases type 4B and 4D (PDE4) splice variants by cAMP signaling in primary cortical neurons.
    D'Sa C; Tolbert LM; Conti M; Duman RS
    J Neurochem; 2002 May; 81(4):745-57. PubMed ID: 12065634
    [TBL] [Abstract][Full Text] [Related]  

  • 16. DISC1, PDE4B, and NDE1 at the centrosome and synapse.
    Bradshaw NJ; Ogawa F; Antolin-Fontes B; Chubb JE; Carlyle BC; Christie S; Claessens A; Porteous DJ; Millar JK
    Biochem Biophys Res Commun; 2008 Dec; 377(4):1091-6. PubMed ID: 18983980
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synergistic interactions between PDE4B and GSK-3: DISC1 mutant mice.
    Lipina TV; Wang M; Liu F; Roder JC
    Neuropharmacology; 2012 Mar; 62(3):1252-62. PubMed ID: 21376063
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Molecular cloning and transient expression in COS7 cells of a novel human PDE4B cAMP-specific phosphodiesterase, HSPDE4B3.
    Huston E; Lumb S; Russell A; Catterall C; Ross AH; Steele MR; Bolger GB; Perry MJ; Owens RJ; Houslay MD
    Biochem J; 1997 Dec; 328 ( Pt 2)(Pt 2):549-58. PubMed ID: 9371714
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Noradrenergic lesions differentially alter the expression of two subtypes of low Km cAMP-sensitive phosphodiesterase type 4 (PDE4A and PDE4B) in rat brain.
    Farooqui SM; Zhang K; Makhay M; Jackson K; Farooqui SQ; Cherry JA; O'Donnell JM
    Brain Res; 2000 Jun; 867(1-2):52-61. PubMed ID: 10837797
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Role of disrupted in schizophrenia 1 (DISC1) in stress-induced prefrontal cognitive dysfunction.
    Gamo NJ; Duque A; Paspalas CD; Kata A; Fine R; Boven L; Bryan C; Lo T; Anighoro K; Bermudez L; Peng K; Annor A; Raja A; Mansson E; Taylor SR; Patel K; Simen AA; Arnsten AF
    Transl Psychiatry; 2013 Dec; 3(12):e328. PubMed ID: 24301646
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 23.