201 related articles for article (PubMed ID: 16299552)
1. [32P]2-iodo-N6-methyl-(N)-methanocarba-2'-deoxyadenosine-3',5'-bisphosphate ([32P]MRS2500), a novel radioligand for quantification of native P2Y1 receptors.
Houston D; Ohno M; Nicholas RA; Jacobson KA; Harden TK
Br J Pharmacol; 2006 Mar; 147(5):459-67. PubMed ID: 16299552
[TBL] [Abstract][Full Text] [Related]
2. Quantification of recombinant and platelet P2Y(1) receptors utilizing a [(125)I]-labeled high-affinity antagonist 2-iodo-N(6)-methyl-(N)-methanocarba-2'-deoxyadenosine-3',5'-bisphosphate ([(125)I]MRS2500).
Ohlmann P; de Castro S; Brown GG; Gachet C; Jacobson KA; Harden TK
Pharmacol Res; 2010 Oct; 62(4):344-51. PubMed ID: 20594939
[TBL] [Abstract][Full Text] [Related]
3. Quantitation of the P2Y(1) receptor with a high affinity radiolabeled antagonist.
Waldo GL; Corbitt J; Boyer JL; Ravi G; Kim HS; Ji XD; Lacy J; Jacobson KA; Harden TK
Mol Pharmacol; 2002 Nov; 62(5):1249-57. PubMed ID: 12391289
[TBL] [Abstract][Full Text] [Related]
4. MRS2500 [2-iodo-N6-methyl-(N)-methanocarba-2'-deoxyadenosine-3',5'-bisphosphate], a potent, selective, and stable antagonist of the platelet P2Y1 receptor with strong antithrombotic activity in mice.
Hechler B; Nonne C; Roh EJ; Cattaneo M; Cazenave JP; Lanza F; Jacobson KA; Gachet C
J Pharmacol Exp Ther; 2006 Feb; 316(2):556-63. PubMed ID: 16236815
[TBL] [Abstract][Full Text] [Related]
5. 2-Substitution of adenine nucleotide analogues containing a bicyclo[3.1.0]hexane ring system locked in a northern conformation: enhanced potency as P2Y1 receptor antagonists.
Kim HS; Ohno M; Xu B; Kim HO; Choi Y; Ji XD; Maddileti S; Marquez VE; Harden TK; Jacobson KA
J Med Chem; 2003 Nov; 46(23):4974-87. PubMed ID: 14584948
[TBL] [Abstract][Full Text] [Related]
6. 2-Chloro N(6)-methyl-(N)-methanocarba-2'-deoxyadenosine-3',5'-bisphosphate is a selective high affinity P2Y(1) receptor antagonist.
Boyer JL; Adams M; Ravi RG; Jacobson KA; Harden TK
Br J Pharmacol; 2002 Apr; 135(8):2004-10. PubMed ID: 11959804
[TBL] [Abstract][Full Text] [Related]
7. Antiaggregatory activity in human platelets of potent antagonists of the P2Y 1 receptor.
Cattaneo M; Lecchi A; Ohno M; Joshi BV; Besada P; Tchilibon S; Lombardi R; Bischofberger N; Harden TK; Jacobson KA
Biochem Pharmacol; 2004 Nov; 68(10):1995-2002. PubMed ID: 15476670
[TBL] [Abstract][Full Text] [Related]
8. Agonist binding and Gq-stimulating activities of the purified human P2Y1 receptor.
Waldo GL; Harden TK
Mol Pharmacol; 2004 Feb; 65(2):426-36. PubMed ID: 14742685
[TBL] [Abstract][Full Text] [Related]
9. 2-Chloro-N6-methyl-(N)-methanocarba-2'-deoxyadenosine-3',5'-bisphosphate is a selective high affinity P2Y1 receptor antagonist: commentary on Boyer et al.
King BF
Br J Pharmacol; 2002 Apr; 135(8):1839-40. PubMed ID: 11959784
[No Abstract] [Full Text] [Related]
10. Pharmacological characterization of purinergic inhibitory neuromuscular transmission in the human colon.
Gallego D; Gil V; Aleu J; Martinez-Cutillas M; Clavé P; Jimenez M
Neurogastroenterol Motil; 2011 Aug; 23(8):792-e338. PubMed ID: 21585621
[TBL] [Abstract][Full Text] [Related]
11. Competitive and selective antagonism of P2Y1 receptors by N6-methyl 2'-deoxyadenosine 3',5'-bisphosphate.
Boyer JL; Mohanram A; Camaioni E; Jacobson KA; Harden TK
Br J Pharmacol; 1998 May; 124(1):1-3. PubMed ID: 9630335
[TBL] [Abstract][Full Text] [Related]
12. Distribution and characterisation of [3H]alpha,beta-methylene ATP binding sites in the rat.
Michel AD; Humphrey PP
Naunyn Schmiedebergs Arch Pharmacol; 1993 Dec; 348(6):608-17. PubMed ID: 8133903
[TBL] [Abstract][Full Text] [Related]
13. Methanocarba modification of uracil and adenine nucleotides: high potency of Northern ring conformation at P2Y1, P2Y2, P2Y4, and P2Y11 but not P2Y6 receptors.
Kim HS; Ravi RG; Marquez VE; Maddileti S; Wihlborg AK; Erlinge D; Malmsjö M; Boyer JL; Harden TK; Jacobson KA
J Med Chem; 2002 Jan; 45(1):208-18. PubMed ID: 11754592
[TBL] [Abstract][Full Text] [Related]
14. Characterization of a P2Y purinoceptor in the brain.
Simon J; Webb TE; Barnard EA
Pharmacol Toxicol; 1995 May; 76(5):302-7. PubMed ID: 7567779
[TBL] [Abstract][Full Text] [Related]
15. Synthesis, biological activity, and molecular modeling of ribose-modified deoxyadenosine bisphosphate analogues as P2Y(1) receptor ligands.
Nandanan E; Jang SY; Moro S; Kim HO; Siddiqui MA; Russ P; Marquez VE; Busson R; Herdewijn P; Harden TK; Boyer JL; Jacobson KA
J Med Chem; 2000 Mar; 43(5):829-42. PubMed ID: 10715151
[TBL] [Abstract][Full Text] [Related]
16. Development of selective high affinity antagonists, agonists, and radioligands for the P2Y1 receptor.
Houston D; Costanzi S; Jacobson KA; Harden TK
Comb Chem High Throughput Screen; 2008 Jul; 11(6):410-9. PubMed ID: 18673269
[TBL] [Abstract][Full Text] [Related]
17. Structure-activity relationships of bisphosphate nucleotide derivatives as P2Y1 receptor antagonists and partial agonists.
Nandanan E; Camaioni E; Jang SY; Kim YC; Cristalli G; Herdewijn P; Secrist JA; Tiwari KN; Mohanram A; Harden TK; Boyer JL; Jacobson KA
J Med Chem; 1999 May; 42(9):1625-38. PubMed ID: 10229631
[TBL] [Abstract][Full Text] [Related]
18. Participation of peripheral P2Y1, P2Y6 and P2Y11 receptors in formalin-induced inflammatory pain in rats.
Barragán-Iglesias P; Mendoza-Garcés L; Pineda-Farias JB; Solano-Olivares V; Rodríguez-Silverio J; Flores-Murrieta FJ; Granados-Soto V; Rocha-González HI
Pharmacol Biochem Behav; 2015 Jan; 128():23-32. PubMed ID: 25449358
[TBL] [Abstract][Full Text] [Related]
19. Molecular recognition at adenine nucleotide (P2) receptors in platelets.
Jacobson KA; Mamedova L; Joshi BV; Besada P; Costanzi S
Semin Thromb Hemost; 2005 Apr; 31(2):205-16. PubMed ID: 15852224
[TBL] [Abstract][Full Text] [Related]
20. Immunoreactive localisation of P2Y1 receptors within the rat and human nodose ganglia and rat brainstem: comparison with [alpha 33P]deoxyadenosine 5'-triphosphate autoradiography.
Fong AY; Krstew EV; Barden J; Lawrence AJ
Neuroscience; 2002; 113(4):809-23. PubMed ID: 12182888
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
