These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

313 related articles for article (PubMed ID: 16300786)

  • 1. Molecular basis for nucleotide-binding specificity: role of the exocyclic amino group "N2" in recognition by a guanylyl-ribonuclease.
    Schrift GL; Waldron TT; Timmons MA; Ramaswamy S; Kearney WR; Murphy KP
    J Mol Biol; 2006 Jan; 355(1):72-84. PubMed ID: 16300786
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The salt-dependence of a protein-ligand interaction: ion-protein binding energetics.
    Waldron TT; Schrift GL; Murphy KP
    J Mol Biol; 2005 Feb; 346(3):895-905. PubMed ID: 15713470
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Crystal structures of the ribonuclease MC1 mutants N71T and N71S in complex with 5'-GMP: structural basis for alterations in substrate specificity.
    Numata T; Suzuki A; Kakuta Y; Kimura K; Yao M; Tanaka I; Yoshida Y; Ueda T; Kimura M
    Biochemistry; 2003 May; 42(18):5270-8. PubMed ID: 12731868
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Analysis of internal motions of RNase T1 complexed with a productive substrate involving 15N NMR relaxation measurements.
    Yoshida Y; Tanaka M; Ohkuri T; Tanaka Y; Imoto T; Ueda T
    J Biochem; 2006 Jul; 140(1):43-8. PubMed ID: 16877767
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Crystal structure reveals two alternative conformations in the active site of ribonuclease Sa2.
    Sevcík J; Dauter Z; Wilson KS
    Acta Crystallogr D Biol Crystallogr; 2004 Jul; 60(Pt 7):1198-204. PubMed ID: 15213380
    [TBL] [Abstract][Full Text] [Related]  

  • 6. pH dependence of binding reactions from free energy simulations and macroscopic continuum electrostatic calculations: application to 2'GMP/3'GMP binding to ribonuclease T1 and implications for catalysis.
    MacKerell AD; Sommer MS; Karplus M
    J Mol Biol; 1995 Apr; 247(4):774-807. PubMed ID: 7723031
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Zinc(II)-mediated inhibition of ribonuclease Sa by an N-hydroxyurea nucleotide and its basis.
    Makarov AA; Yakovlev GI; Mitkevich VA; Higgin JJ; Raines RT
    Biochem Biophys Res Commun; 2004 Jun; 319(1):152-6. PubMed ID: 15158454
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Three-dimensional structure of ribonuclease T1 complexed with an isosteric phosphonate substrate analogue of GpU: alternate substrate binding modes and catalysis.
    Arni RK; Watanabe L; Ward RJ; Kreitman RJ; Kumar K; Walz FG
    Biochemistry; 1999 Feb; 38(8):2452-61. PubMed ID: 10029539
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Crystal structures of ribonuclease F1 of Fusarium moniliforme in its free form and in complex with 2'GMP.
    Vassylyev DG; Katayanagi K; Ishikawa K; Tsujimoto-Hirano M; Danno M; Pähler A; Matsumoto O; Matsushima M; Yoshida H; Morikawa K
    J Mol Biol; 1993 Apr; 230(3):979-96. PubMed ID: 8386773
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Calculation of the relative binding free energy of 2'GMP and 2'AMP to ribonuclease T1 using molecular dynamics/free energy perturbation approaches.
    Hirono S; Kollman PA
    J Mol Biol; 1990 Mar; 212(1):197-209. PubMed ID: 2157020
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structural analysis of an RNase T1 variant with an altered guanine binding segment.
    Höschler K; Hoier H; Hubner B; Saenger W; Orth P; Hahn U
    J Mol Biol; 1999 Dec; 294(5):1231-8. PubMed ID: 10600381
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Temperature dependence of the backbone dynamics of ribonuclease A in the ground state and bound to the inhibitor 5'-phosphothymidine (3'-5')pyrophosphate adenosine 3'-phosphate.
    Kovrigin EL; Cole R; Loria JP
    Biochemistry; 2003 May; 42(18):5279-91. PubMed ID: 12731869
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Site specific point mutation changes specificity: a molecular modeling study by free energy simulations and enzyme kinetics of the thermodynamics in ribonuclease T1 substrate interactions.
    Elofsson A; Kulinski T; Rigler R; Nilsson L
    Proteins; 1993 Oct; 17(2):161-75. PubMed ID: 8265564
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Selective binding of monovalent cations to the stacking G-quartet structure formed by guanosine 5'-monophosphate: a solid-state NMR study.
    Wong A; Wu G
    J Am Chem Soc; 2003 Nov; 125(45):13895-905. PubMed ID: 14599230
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The structure of substrate-free microbial ribonuclease binase and of its complexes with 3'GMP and sulfate ions.
    Polyakov KM; Lebedev AA; Okorokov AL; Panov KI; Schulga AA; Pavlovsky AG; Karpeisky MY; Dodson GG
    Acta Crystallogr D Biol Crystallogr; 2002 May; 58(Pt 5):744-50. PubMed ID: 11976484
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Recognition templates for predicting adenylate-binding sites in proteins.
    Zhao S; Morris GM; Olson AJ; Goodsell DS
    J Mol Biol; 2001 Dec; 314(5):1245-55. PubMed ID: 11743737
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Tyrosine hydrogen bonds make a large contribution to protein stability.
    Pace CN; Horn G; Hebert EJ; Bechert J; Shaw K; Urbanikova L; Scholtz JM; Sevcik J
    J Mol Biol; 2001 Sep; 312(2):393-404. PubMed ID: 11554795
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Binding modes of inhibitors to ribonuclease T1 as elucidated by the analysis of two-dimensional NMR.
    Shimada I; Inagaki F
    Nucleic Acids Symp Ser; 1989; (21):57-8. PubMed ID: 2514414
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A calorimetric study of the thermal stability of barnase and its interaction with 3'GMP.
    Martínez JC; el Harrous M; Filimonov VV; Mateo PL; Fersht AR
    Biochemistry; 1994 Apr; 33(13):3919-26. PubMed ID: 8142395
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Crystal structure of the complex RNase Sa-barstar at 1.7 A resolution.
    Urbániková L; Sevcík J
    Gen Physiol Biophys; 1998 Jun; 17 Suppl 1():12-4. PubMed ID: 9789743
    [No Abstract]   [Full Text] [Related]  

    [Next]    [New Search]
    of 16.