BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

315 related articles for article (PubMed ID: 16300786)

  • 1. Molecular basis for nucleotide-binding specificity: role of the exocyclic amino group "N2" in recognition by a guanylyl-ribonuclease.
    Schrift GL; Waldron TT; Timmons MA; Ramaswamy S; Kearney WR; Murphy KP
    J Mol Biol; 2006 Jan; 355(1):72-84. PubMed ID: 16300786
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The salt-dependence of a protein-ligand interaction: ion-protein binding energetics.
    Waldron TT; Schrift GL; Murphy KP
    J Mol Biol; 2005 Feb; 346(3):895-905. PubMed ID: 15713470
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Crystal structures of the ribonuclease MC1 mutants N71T and N71S in complex with 5'-GMP: structural basis for alterations in substrate specificity.
    Numata T; Suzuki A; Kakuta Y; Kimura K; Yao M; Tanaka I; Yoshida Y; Ueda T; Kimura M
    Biochemistry; 2003 May; 42(18):5270-8. PubMed ID: 12731868
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Analysis of internal motions of RNase T1 complexed with a productive substrate involving 15N NMR relaxation measurements.
    Yoshida Y; Tanaka M; Ohkuri T; Tanaka Y; Imoto T; Ueda T
    J Biochem; 2006 Jul; 140(1):43-8. PubMed ID: 16877767
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Crystal structure reveals two alternative conformations in the active site of ribonuclease Sa2.
    Sevcík J; Dauter Z; Wilson KS
    Acta Crystallogr D Biol Crystallogr; 2004 Jul; 60(Pt 7):1198-204. PubMed ID: 15213380
    [TBL] [Abstract][Full Text] [Related]  

  • 6. pH dependence of binding reactions from free energy simulations and macroscopic continuum electrostatic calculations: application to 2'GMP/3'GMP binding to ribonuclease T1 and implications for catalysis.
    MacKerell AD; Sommer MS; Karplus M
    J Mol Biol; 1995 Apr; 247(4):774-807. PubMed ID: 7723031
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Zinc(II)-mediated inhibition of ribonuclease Sa by an N-hydroxyurea nucleotide and its basis.
    Makarov AA; Yakovlev GI; Mitkevich VA; Higgin JJ; Raines RT
    Biochem Biophys Res Commun; 2004 Jun; 319(1):152-6. PubMed ID: 15158454
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Three-dimensional structure of ribonuclease T1 complexed with an isosteric phosphonate substrate analogue of GpU: alternate substrate binding modes and catalysis.
    Arni RK; Watanabe L; Ward RJ; Kreitman RJ; Kumar K; Walz FG
    Biochemistry; 1999 Feb; 38(8):2452-61. PubMed ID: 10029539
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Crystal structures of ribonuclease F1 of Fusarium moniliforme in its free form and in complex with 2'GMP.
    Vassylyev DG; Katayanagi K; Ishikawa K; Tsujimoto-Hirano M; Danno M; Pähler A; Matsumoto O; Matsushima M; Yoshida H; Morikawa K
    J Mol Biol; 1993 Apr; 230(3):979-96. PubMed ID: 8386773
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Calculation of the relative binding free energy of 2'GMP and 2'AMP to ribonuclease T1 using molecular dynamics/free energy perturbation approaches.
    Hirono S; Kollman PA
    J Mol Biol; 1990 Mar; 212(1):197-209. PubMed ID: 2157020
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structural analysis of an RNase T1 variant with an altered guanine binding segment.
    Höschler K; Hoier H; Hubner B; Saenger W; Orth P; Hahn U
    J Mol Biol; 1999 Dec; 294(5):1231-8. PubMed ID: 10600381
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Temperature dependence of the backbone dynamics of ribonuclease A in the ground state and bound to the inhibitor 5'-phosphothymidine (3'-5')pyrophosphate adenosine 3'-phosphate.
    Kovrigin EL; Cole R; Loria JP
    Biochemistry; 2003 May; 42(18):5279-91. PubMed ID: 12731869
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Site specific point mutation changes specificity: a molecular modeling study by free energy simulations and enzyme kinetics of the thermodynamics in ribonuclease T1 substrate interactions.
    Elofsson A; Kulinski T; Rigler R; Nilsson L
    Proteins; 1993 Oct; 17(2):161-75. PubMed ID: 8265564
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Selective binding of monovalent cations to the stacking G-quartet structure formed by guanosine 5'-monophosphate: a solid-state NMR study.
    Wong A; Wu G
    J Am Chem Soc; 2003 Nov; 125(45):13895-905. PubMed ID: 14599230
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The structure of substrate-free microbial ribonuclease binase and of its complexes with 3'GMP and sulfate ions.
    Polyakov KM; Lebedev AA; Okorokov AL; Panov KI; Schulga AA; Pavlovsky AG; Karpeisky MY; Dodson GG
    Acta Crystallogr D Biol Crystallogr; 2002 May; 58(Pt 5):744-50. PubMed ID: 11976484
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Recognition templates for predicting adenylate-binding sites in proteins.
    Zhao S; Morris GM; Olson AJ; Goodsell DS
    J Mol Biol; 2001 Dec; 314(5):1245-55. PubMed ID: 11743737
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Tyrosine hydrogen bonds make a large contribution to protein stability.
    Pace CN; Horn G; Hebert EJ; Bechert J; Shaw K; Urbanikova L; Scholtz JM; Sevcik J
    J Mol Biol; 2001 Sep; 312(2):393-404. PubMed ID: 11554795
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Binding modes of inhibitors to ribonuclease T1 as elucidated by the analysis of two-dimensional NMR.
    Shimada I; Inagaki F
    Nucleic Acids Symp Ser; 1989; (21):57-8. PubMed ID: 2514414
    [TBL] [Abstract][Full Text] [Related]  

  • 19. A calorimetric study of the thermal stability of barnase and its interaction with 3'GMP.
    Martínez JC; el Harrous M; Filimonov VV; Mateo PL; Fersht AR
    Biochemistry; 1994 Apr; 33(13):3919-26. PubMed ID: 8142395
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Crystal structure of the complex RNase Sa-barstar at 1.7 A resolution.
    Urbániková L; Sevcík J
    Gen Physiol Biophys; 1998 Jun; 17 Suppl 1():12-4. PubMed ID: 9789743
    [No Abstract]   [Full Text] [Related]  

    [Next]    [New Search]
    of 16.