BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

297 related articles for article (PubMed ID: 16302803)

  • 1. Identification of the structural requirements of the receptor-binding affinity of diphenolic azoles to estrogen receptors alpha and beta by three-dimensional quantitative structure-activity relationship and structure-activity relationship analysis.
    Demyttenaere-Kovatcheva A; Cronin MT; Benfenati E; Roncaglioni A; Lopiparo E
    J Med Chem; 2005 Dec; 48(24):7628-36. PubMed ID: 16302803
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Comparison of estrogen receptor alpha and beta subtypes based on comparative molecular field analysis (CoMFA).
    Xing L; Welsh WJ; Tong W; Perkins R; Sheehan DM
    SAR QSAR Environ Res; 1999; 10(2-3):215-37. PubMed ID: 10491851
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Use of binding energy in comparative molecular field analysis of isoform selective estrogen receptor ligands.
    Wolohan P; Reichert DE
    J Mol Graph Model; 2004 Sep; 23(1):23-38. PubMed ID: 15331051
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Insight into the structural requirements of urokinase-type plasminogen activator inhibitors based on 3D QSAR CoMFA/CoMSIA models.
    Bhongade BA; Gadad AK
    J Med Chem; 2006 Jan; 49(2):475-89. PubMed ID: 16420035
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Induction of the estrogen specific mitogenic response of MCF-7 cells by selected analogues of estradiol-17 beta: a 3D QSAR study.
    Wiese TE; Polin LA; Palomino E; Brooks SC
    J Med Chem; 1997 Oct; 40(22):3659-69. PubMed ID: 9357533
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Design and synthesis of aryl diphenolic azoles as potent and selective estrogen receptor-beta ligands.
    Malamas MS; Manas ES; McDevitt RE; Gunawan I; Xu ZB; Collini MD; Miller CP; Dinh T; Henderson RA; Keith JC; Harris HA
    J Med Chem; 2004 Oct; 47(21):5021-40. PubMed ID: 15456246
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structural and chemical basis for enhanced affinity and potency for a large series of estrogen receptor ligands: 2D and 3D QSAR studies.
    Salum Lde B; Polikarpov I; Andricopulo AD
    J Mol Graph Model; 2007 Sep; 26(2):434-42. PubMed ID: 17349808
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Development and validation of an average mammalian estrogen receptor-based QSAR model.
    Mekenya O; Kamenska V; Serafimova R; Poellinger L; Brouwer A; Walker J
    SAR QSAR Environ Res; 2002 Oct; 13(6):579-95. PubMed ID: 12479373
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Three-dimensional quantitative structure-activity relationship study of nonsteroidal estrogen receptor ligands using the comparative molecular field analysis/cross-validated r2-guided region selection approach.
    Sadler BR; Cho SJ; Ishaq KS; Chae K; Korach KS
    J Med Chem; 1998 Jun; 41(13):2261-7. PubMed ID: 9632359
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structure-based quantitative structure--activity relationship modeling of estrogen receptor β-ligands.
    Dong X; Hilliard SG; Zheng W
    Future Med Chem; 2011 Jun; 3(8):933-45. PubMed ID: 21707397
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Synthesis and biological evaluation of phenolic 4,5-dihydroisoxazoles and 3-hydroxy ketones as estrogen receptor alpha and beta agonists.
    Poutiainen PK; Venäläinen TA; Peräkylä M; Matilainen JM; Väisänen S; Honkakoski P; Laatikainen R; Pulkkinen JT
    Bioorg Med Chem; 2010 May; 18(10):3437-47. PubMed ID: 20430632
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structure-based approach for the study of estrogen receptor binding affinity and subtype selectivity.
    Salum LB; Polikarpov I; Andricopulo AD
    J Chem Inf Model; 2008 Nov; 48(11):2243-53. PubMed ID: 18937440
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Insights into the structural requirements of farnesyltransferase inhibitors as potential anti-tumor agents based on 3D-QSAR CoMFA and CoMSIA models.
    Puntambekar DS; Giridhar R; Yadav MR
    Eur J Med Chem; 2008 Jan; 43(1):142-54. PubMed ID: 17448576
    [TBL] [Abstract][Full Text] [Related]  

  • 14. 3D-QSAR and molecular docking studies of selective agonists for the thyroid hormone receptor beta.
    Du J; Qin J; Liu H; Yao X
    J Mol Graph Model; 2008 Sep; 27(2):95-104. PubMed ID: 18436460
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Three-dimensional quantitative structure-activity relationship of interleukin 1-beta converting enzyme inhibitors: A comparative molecular field analysis study.
    Kulkarni SS; Kulkarni VM
    J Med Chem; 1999 Feb; 42(3):373-80. PubMed ID: 9986707
    [TBL] [Abstract][Full Text] [Related]  

  • 16. 3D-QSAR studies for the binding affinity toward (R, S)-2-amino-3-(3-hydroxy-5-methylisoxazol-4-yl)-propionic acid receptor.
    Sharma RN; Thakar H; Vasu KK; Chaturvedi SC
    Acta Pharm; 2008 Sep; 58(3):335-45. PubMed ID: 19103570
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis and characterization of 3-arylquinazolinone and 3-arylquinazolinethione derivatives as selective estrogen receptor beta modulators.
    Güngör T; Chen Y; Golla R; Ma Z; Corte JR; Northrop JP; Bin B; Dickson JK; Stouch T; Zhou R; Johnson SE; Seethala R; Feyen JH
    J Med Chem; 2006 Apr; 49(8):2440-55. PubMed ID: 16610787
    [TBL] [Abstract][Full Text] [Related]  

  • 18. New insights into the SAR and binding modes of bis(hydroxyphenyl)thiophenes and -benzenes: influence of additional substituents on 17beta-hydroxysteroid dehydrogenase type 1 (17beta-HSD1) inhibitory activity and selectivity.
    Bey E; Marchais-Oberwinkler S; Negri M; Kruchten P; Oster A; Klein T; Spadaro A; Werth R; Frotscher M; Birk B; Hartmann RW
    J Med Chem; 2009 Nov; 52(21):6724-43. PubMed ID: 19831396
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Comparative molecular field analysis (CoMFA) model using a large diverse set of natural, synthetic and environmental chemicals for binding to the androgen receptor.
    Hong H; Fang H; Xie Q; Perkins R; Sheehan DM; Tong W
    SAR QSAR Environ Res; 2003; 14(5-6):373-88. PubMed ID: 14758981
    [TBL] [Abstract][Full Text] [Related]  

  • 20. QSAR study of a large set of 3-pyridyl ethers as ligands of the alpha4beta2 nicotinic acetylcholine receptor.
    Zhang H; Li H; Ma Q
    J Mol Graph Model; 2007 Jul; 26(1):226-35. PubMed ID: 17208024
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.