185 related articles for article (PubMed ID: 16303304)
1. Thyroid receptor ligands. Part 4: 4'-amido bioisosteric ligands selective for the thyroid hormone receptor beta.
Li YL; Litten C; Koehler KF; Mellström K; Garg N; Garcia Collazo AM; Färnegård M; Grynfarb M; Husman B; Sandberg J; Malm J
Bioorg Med Chem Lett; 2006 Feb; 16(4):884-6. PubMed ID: 16303304
[TBL] [Abstract][Full Text] [Related]
2. Thyroid receptor ligands. 1. Agonist ligands selective for the thyroid receptor beta1.
Ye L; Li YL; Mellström K; Mellin C; Bladh LG; Koehler K; Garg N; Garcia Collazo AM; Litten C; Husman B; Persson K; Ljunggren J; Grover G; Sleph PG; George R; Malm J
J Med Chem; 2003 Apr; 46(9):1580-8. PubMed ID: 12699376
[TBL] [Abstract][Full Text] [Related]
3. Thyroid receptor ligands. Part 2: Thyromimetics with improved selectivity for the thyroid hormone receptor beta.
Hangeland JJ; Doweyko AM; Dejneka T; Friends TJ; Devasthale P; Mellström K; Sandberg J; Grynfarb M; Sack JS; Einspahr H; Färnegårdh M; Husman B; Ljunggren J; Koehler K; Sheppard C; Malm J; Ryono DE
Bioorg Med Chem Lett; 2004 Jul; 14(13):3549-53. PubMed ID: 15177471
[TBL] [Abstract][Full Text] [Related]
4. Design and synthesis of novel 3-hydroxy-cyclobut-3-ene-1,2-dione derivatives as thyroid hormone receptor beta (TR-beta) selective ligands.
Raval S; Raval P; Bandyopadhyay D; Soni K; Yevale D; Jogiya D; Modi H; Joharapurkar A; Gandhi N; Jain MR; Patel PR
Bioorg Med Chem Lett; 2008 Jul; 18(14):3919-24. PubMed ID: 18585912
[TBL] [Abstract][Full Text] [Related]
5. Thyroid receptor ligands. Part 5: novel bicyclic agonist ligands selective for the thyroid hormone receptor beta.
Garcia Collazo AM; Koehler KF; Garg N; Färnegårdh M; Husman B; Ye L; Ljunggren J; Mellström K; Sandberg J; Grynfarb M; Ahola H; Malm J
Bioorg Med Chem Lett; 2006 Mar; 16(5):1240-4. PubMed ID: 16338239
[TBL] [Abstract][Full Text] [Related]
6. Role of halogen bonds in thyroid hormone receptor selectivity: pharmacophore-based 3D-QSSR studies.
Valadares NF; Salum LB; Polikarpov I; Andricopulo AD; Garratt RC
J Chem Inf Model; 2009 Nov; 49(11):2606-16. PubMed ID: 19863110
[TBL] [Abstract][Full Text] [Related]
7. A new class of high affinity thyromimetics containing a phenyl-naphthylene core.
Hangeland JJ; Friends TJ; Doweyko AM; Mellström K; Sandberg J; Grynfarb M; Ryono DE
Bioorg Med Chem Lett; 2005 Oct; 15(20):4579-84. PubMed ID: 16099653
[TBL] [Abstract][Full Text] [Related]
8. Only subtle protein conformational adaptations are required for ligand binding to thyroid hormone receptors: simulations using a novel multipoint steered molecular dynamics approach.
Martínez L; Polikarpov I; Skaf MS
J Phys Chem B; 2008 Aug; 112(34):10741-51. PubMed ID: 18681473
[TBL] [Abstract][Full Text] [Related]
9. Thyroid receptor ligands. 3. Design and synthesis of 3,5-dihalo-4-alkoxyphenylalkanoic acids as indirect antagonists of the thyroid hormone receptor.
Hedfors A; Appelqvist T; Carlsson B; Bladh LG; Litten C; Agback P; Grynfarb M; Koehler KF; Malm J
J Med Chem; 2005 May; 48(9):3114-7. PubMed ID: 15857115
[TBL] [Abstract][Full Text] [Related]
10. Structural rearrangements in the thyroid hormone receptor hinge domain and their putative role in the receptor function.
Nascimento AS; Dias SM; Nunes FM; Aparício R; Ambrosio AL; Bleicher L; Figueira AC; Santos MA; de Oliveira Neto M; Fischer H; Togashi M; Craievich AF; Garratt RC; Baxter JD; Webb P; Polikarpov I
J Mol Biol; 2006 Jul; 360(3):586-98. PubMed ID: 16781732
[TBL] [Abstract][Full Text] [Related]
11. Development of a thyroid hormone receptor targeting conjugate.
Zheng J; Hashimoto A; Putnam M; Miller K; Koh JT
Bioconjug Chem; 2008 Jun; 19(6):1227-34. PubMed ID: 18507428
[TBL] [Abstract][Full Text] [Related]
12. Thyroid receptor ligands. Part 7: Indirect antagonists of the thyroid hormone receptor with improved affinity.
Malm J; Gordon S; Brandt P; Carlsson B; Agback P; Bäckbro Saeidi A; Sandberg J
Bioorg Med Chem Lett; 2007 Apr; 17(7):2018-21. PubMed ID: 17254783
[TBL] [Abstract][Full Text] [Related]
13. [Thyroid hormones and their precursors I. Biochemical properties].
Tóth G; Noszál B
Acta Pharm Hung; 2013; 83(2):35-45. PubMed ID: 23926648
[TBL] [Abstract][Full Text] [Related]
14. Crystallization and preliminary X-ray diffraction studies of isoform alpha1 of the human thyroid hormone receptor ligand-binding domain.
Nunes FM; Aparicio R; Santos MA; Portugal RV; Dias SM; Neves FA; Simeoni LA; Baxter JD; Webb P; Polikarpov I
Acta Crystallogr D Biol Crystallogr; 2004 Oct; 60(Pt 10):1867-70. PubMed ID: 15388935
[TBL] [Abstract][Full Text] [Related]
15. N-(substituted-anilinoethyl)amides: design, synthesis, and pharmacological characterization of a new class of melatonin receptor ligands.
Rivara S; Lodola A; Mor M; Bedini A; Spadoni G; Lucini V; Pannacci M; Fraschini F; Scaglione F; Sanchez RO; Gobbi G; Tarzia G
J Med Chem; 2007 Dec; 50(26):6618-26. PubMed ID: 18052314
[TBL] [Abstract][Full Text] [Related]
16. Design, synthesis, and X-ray structure of potent memapsin 2 (beta-secretase) inhibitors with isophthalamide derivatives as the P2-P3-ligands.
Ghosh AK; Kumaragurubaran N; Hong L; Kulkarni SS; Xu X; Chang W; Weerasena V; Turner R; Koelsch G; Bilcer G; Tang J
J Med Chem; 2007 May; 50(10):2399-407. PubMed ID: 17432843
[TBL] [Abstract][Full Text] [Related]
17. Thyroid receptor ligands. Part 8: Thyromimetics derived from N-acylated-alpha-amino acid derivatives displaying modulated pharmacological selectivity compared with KB-141.
Garg N; Li YL; Garcia Collazo AM; Litten C; Ryono DE; Zhang M; Caringal Y; Brigance RP; Meng W; Washburn WN; Agback P; Mellström K; Rehnmark S; Rahimi-Ghadim M; Norin T; Grynfarb M; Sandberg J; Grover G; Malm J
Bioorg Med Chem Lett; 2007 Aug; 17(15):4131-4. PubMed ID: 17543524
[TBL] [Abstract][Full Text] [Related]
18. Design, synthesis, and structure-activity relationship (SAR) of N-[7-(4-hydroxyphenoxy)-6-methylindan-4-yl]malonamic acids as thyroid hormone receptor β (TRβ) selective agonists.
Shiohara H; Nakamura T; Kikuchi N; Ozawa T; Matsuzawa A; Nagano R; Ohnota H; Miyamoto T; Ichikawa K; Hashizume K
Bioorg Med Chem; 2013 Feb; 21(3):592-607. PubMed ID: 23276448
[TBL] [Abstract][Full Text] [Related]
19. Potential therapeutic applications of thyroid hormone analogs.
Brenta G; Danzi S; Klein I
Nat Clin Pract Endocrinol Metab; 2007 Sep; 3(9):632-40. PubMed ID: 17710084
[TBL] [Abstract][Full Text] [Related]
20. 2D QSAR studies on thyroid hormone receptor ligands.
Valadares NF; Castilho MS; Polikarpov I; Garratt RC
Bioorg Med Chem; 2007 Jul; 15(13):4609-17. PubMed ID: 17467994
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
