These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

134 related articles for article (PubMed ID: 16303768)

  • 1. Down-regulation of endogenous amyloid precursor protein processing due to cellular aging.
    Kern A; Roempp B; Prager K; Walter J; Behl C
    J Biol Chem; 2006 Feb; 281(5):2405-13. PubMed ID: 16303768
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Nicastrin is required for assembly of presenilin/gamma-secretase complexes to mediate Notch signaling and for processing and trafficking of beta-amyloid precursor protein in mammals.
    Li T; Ma G; Cai H; Price DL; Wong PC
    J Neurosci; 2003 Apr; 23(8):3272-7. PubMed ID: 12716934
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The discrepancy between presenilin subcellular localization and gamma-secretase processing of amyloid precursor protein.
    Cupers P; Bentahir M; Craessaerts K; Orlans I; Vanderstichele H; Saftig P; De Strooper B; Annaert W
    J Cell Biol; 2001 Aug; 154(4):731-40. PubMed ID: 11502763
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Failure of the interaction between presenilin 1 and the substrate of gamma-secretase to produce Abeta in insect cells.
    Pitsi D; Kienlen-Campard P; Octave JN
    J Neurochem; 2002 Oct; 83(2):390-9. PubMed ID: 12423249
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Regulation of amyloid precursor protein processing by presenilin 1 (PS1) and PS2 in PS1 knockout cells.
    Palacino JJ; Berechid BE; Alexander P; Eckman C; Younkin S; Nye JS; Wolozin B
    J Biol Chem; 2000 Jan; 275(1):215-22. PubMed ID: 10617607
    [TBL] [Abstract][Full Text] [Related]  

  • 6. S-palmitoylation of gamma-secretase subunits nicastrin and APH-1.
    Cheng H; Vetrivel KS; Drisdel RC; Meckler X; Gong P; Leem JY; Li T; Carter M; Chen Y; Nguyen P; Iwatsubo T; Tomita T; Wong PC; Green WN; Kounnas MZ; Thinakaran G
    J Biol Chem; 2009 Jan; 284(3):1373-84. PubMed ID: 19028695
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inhibition of intracellular cholesterol transport alters presenilin localization and amyloid precursor protein processing in neuronal cells.
    Runz H; Rietdorf J; Tomic I; de Bernard M; Beyreuther K; Pepperkok R; Hartmann T
    J Neurosci; 2002 Mar; 22(5):1679-89. PubMed ID: 11880497
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Proteolytic processing of the Alzheimer's disease amyloid precursor protein in brain and platelets.
    Evin G; Zhu A; Holsinger RM; Masters CL; Li QX
    J Neurosci Res; 2003 Nov; 74(3):386-92. PubMed ID: 14598315
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Exclusively targeting beta-secretase to lipid rafts by GPI-anchor addition up-regulates beta-site processing of the amyloid precursor protein.
    Cordy JM; Hussain I; Dingwall C; Hooper NM; Turner AJ
    Proc Natl Acad Sci U S A; 2003 Sep; 100(20):11735-40. PubMed ID: 14504402
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The role of presenilin-1 in the gamma-secretase cleavage of the amyloid precursor protein of Alzheimer's disease.
    Octave JN; Essalmani R; Tasiaux B; Menager J; Czech C; Mercken L
    J Biol Chem; 2000 Jan; 275(3):1525-8. PubMed ID: 10636839
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Spatial segregation of gamma-secretase and substrates in distinct membrane domains.
    Vetrivel KS; Cheng H; Kim SH; Chen Y; Barnes NY; Parent AT; Sisodia SS; Thinakaran G
    J Biol Chem; 2005 Jul; 280(27):25892-900. PubMed ID: 15886206
    [TBL] [Abstract][Full Text] [Related]  

  • 12. A role for presenilin 1 in regulating the delivery of amyloid precursor protein to the cell surface.
    Leem JY; Saura CA; Pietrzik C; Christianson J; Wanamaker C; King LT; Veselits ML; Tomita T; Gasparini L; Iwatsubo T; Xu H; Green WN; Koo EH; Thinakaran G
    Neurobiol Dis; 2002 Oct; 11(1):64-82. PubMed ID: 12460547
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Presenilin complexes with the C-terminal fragments of amyloid precursor protein at the sites of amyloid beta-protein generation.
    Xia W; Ray WJ; Ostaszewski BL; Rahmati T; Kimberly WT; Wolfe MS; Zhang J; Goate AM; Selkoe DJ
    Proc Natl Acad Sci U S A; 2000 Aug; 97(16):9299-304. PubMed ID: 10922078
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Association of gamma-secretase with lipid rafts in post-Golgi and endosome membranes.
    Vetrivel KS; Cheng H; Lin W; Sakurai T; Li T; Nukina N; Wong PC; Xu H; Thinakaran G
    J Biol Chem; 2004 Oct; 279(43):44945-54. PubMed ID: 15322084
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Human wild presenilin-1 mimics the effect of the mutant presenilin-1 on the processing of Alzheimer's amyloid precursor protein in PC12D cells.
    Kametani F; Tanaka K; Usami M; Maruyama K; Mori H
    J Neurol Sci; 2001 Jul; 188(1-2):27-31. PubMed ID: 11489281
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Identification of a beta-secretase activity, which truncates amyloid beta-peptide after its presenilin-dependent generation.
    Fluhrer R; Multhaup G; Schlicksupp A; Okochi M; Takeda M; Lammich S; Willem M; Westmeyer G; Bode W; Walter J; Haass C
    J Biol Chem; 2003 Feb; 278(8):5531-8. PubMed ID: 12471021
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Deficiency of presenilin-1 inhibits the normal cleavage of amyloid precursor protein.
    De Strooper B; Saftig P; Craessaerts K; Vanderstichele H; Guhde G; Annaert W; Von Figura K; Van Leuven F
    Nature; 1998 Jan; 391(6665):387-90. PubMed ID: 9450754
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Low density lipoprotein receptor-related protein (LRP) interacts with presenilin 1 and is a competitive substrate of the amyloid precursor protein (APP) for gamma-secretase.
    Lleó A; Waldron E; von Arnim CA; Herl L; Tangredi MM; Peltan ID; Strickland DK; Koo EH; Hyman BT; Pietrzik CU; Berezovska O
    J Biol Chem; 2005 Jul; 280(29):27303-9. PubMed ID: 15917251
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Interaction of the cytosolic domains of sorLA/LR11 with the amyloid precursor protein (APP) and beta-secretase beta-site APP-cleaving enzyme.
    Spoelgen R; von Arnim CA; Thomas AV; Peltan ID; Koker M; Deng A; Irizarry MC; Andersen OM; Willnow TE; Hyman BT
    J Neurosci; 2006 Jan; 26(2):418-28. PubMed ID: 16407538
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Presenilin 1 controls gamma-secretase processing of amyloid precursor protein in pre-golgi compartments of hippocampal neurons.
    Annaert WG; Levesque L; Craessaerts K; Dierinck I; Snellings G; Westaway D; George-Hyslop PS; Cordell B; Fraser P; De Strooper B
    J Cell Biol; 1999 Oct; 147(2):277-94. PubMed ID: 10525535
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.