BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

234 related articles for article (PubMed ID: 16303771)

  • 1. Tissue-type plasminogen activator acts as a cytokine that triggers intracellular signal transduction and induces matrix metalloproteinase-9 gene expression.
    Hu K; Yang J; Tanaka S; Gonias SL; Mars WM; Liu Y
    J Biol Chem; 2006 Jan; 281(4):2120-7. PubMed ID: 16303771
    [TBL] [Abstract][Full Text] [Related]  

  • 2. tPA protects renal interstitial fibroblasts and myofibroblasts from apoptosis.
    Hu K; Lin L; Tan X; Yang J; Bu G; Mars WM; Liu Y
    J Am Soc Nephrol; 2008 Mar; 19(3):503-14. PubMed ID: 18199803
    [TBL] [Abstract][Full Text] [Related]  

  • 3. tPA activates LDL receptor-related protein 1-mediated mitogenic signaling involving the p90RSK and GSK3beta pathway.
    Lin L; Bu G; Mars WM; Reeves WB; Tanaka S; Hu K
    Am J Pathol; 2010 Oct; 177(4):1687-96. PubMed ID: 20724593
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Tissue-type plasminogen activator promotes murine myofibroblast activation through LDL receptor-related protein 1-mediated integrin signaling.
    Hu K; Wu C; Mars WM; Liu Y
    J Clin Invest; 2007 Dec; 117(12):3821-32. PubMed ID: 18037995
    [TBL] [Abstract][Full Text] [Related]  

  • 5. LRP1 assembles unique co-receptor systems to initiate cell signaling in response to tissue-type plasminogen activator and myelin-associated glycoprotein.
    Mantuano E; Lam MS; Gonias SL
    J Biol Chem; 2013 Nov; 288(47):34009-34018. PubMed ID: 24129569
    [TBL] [Abstract][Full Text] [Related]  

  • 6. tPA is a potent mitogen for renal interstitial fibroblasts: role of beta1 integrin/focal adhesion kinase signaling.
    Hao S; Shen H; Hou Y; Mars WM; Liu Y
    Am J Pathol; 2010 Sep; 177(3):1164-75. PubMed ID: 20639453
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Isoflurane Postconditioning Inhibits tPA-Induced Matrix Metalloproteinases Activation After Hypoxic Injury via Low-Density Lipoprotein Receptor-Related Protein and Extracellular Signal-Regulated Kinase Pathway.
    Kim SY; Cheon SY; Kim EJ; Lee JH; Kam EH; Kim JM; Park M; Koo BN
    Neurochem Res; 2017 May; 42(5):1533-1542. PubMed ID: 28303501
    [TBL] [Abstract][Full Text] [Related]  

  • 8. JNK1 differentially regulates osteopontin-induced nuclear factor-inducing kinase/MEKK1-dependent activating protein-1-mediated promatrix metalloproteinase-9 activation.
    Rangaswami H; Bulbule A; Kundu GC
    J Biol Chem; 2005 May; 280(19):19381-92. PubMed ID: 15757900
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Low density lipoprotein receptor-related protein (LRP) is required for lactoferrin-enhanced collagen gel contractile activity of human fibroblasts.
    Takayama Y; Takahashi H; Mizumachi K; Takezawa T
    J Biol Chem; 2003 Jun; 278(24):22112-8. PubMed ID: 12672816
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Signal integration and coincidence detection in the mitogen-activated protein kinase/extracellular signal-regulated kinase (ERK) cascade: concomitant activation of receptor tyrosine kinases and of LRP-1 leads to sustained ERK phosphorylation via down-regulation of dual specificity phosphatases (DUSP1 and -6).
    Geetha N; Mihaly J; Stockenhuber A; Blasi F; Uhrin P; Binder BR; Freissmuth M; Breuss JM
    J Biol Chem; 2011 Jul; 286(29):25663-74. PubMed ID: 21610072
    [TBL] [Abstract][Full Text] [Related]  

  • 11. IL-17 stimulates MMP-1 expression in primary human cardiac fibroblasts via p38 MAPK- and ERK1/2-dependent C/EBP-beta , NF-kappaB, and AP-1 activation.
    Cortez DM; Feldman MD; Mummidi S; Valente AJ; Steffensen B; Vincenti M; Barnes JL; Chandrasekar B
    Am J Physiol Heart Circ Physiol; 2007 Dec; 293(6):H3356-65. PubMed ID: 17921324
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Connective tissue growth factor increases matrix metalloproteinase-2 and suppresses tissue inhibitor of matrix metalloproteinase-2 production by cultured renal interstitial fibroblasts.
    Yang M; Huang H; Li J; Huang W; Wang H
    Wound Repair Regen; 2007; 15(6):817-24. PubMed ID: 18028129
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Novel actions of tissue-type plasminogen activator in chronic kidney disease.
    Hu K; Mars WM; Liu Y
    Front Biosci; 2008 May; 13():5174-86. PubMed ID: 18508579
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Secretion of matrix metalloproteinase-9 by the proinflammatory cytokine, IL-1beta: a role for the dual signalling pathways, Akt and Erk.
    Ruhul Amin AR; Senga T; Oo ML; Thant AA; Hamaguchi M
    Genes Cells; 2003 Jun; 8(6):515-23. PubMed ID: 12786942
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Oncostatin M, an interleukin-6 family cytokine, upregulates matrix metalloproteinase-9 through the mitogen-activated protein kinase kinase-extracellular signal-regulated kinase pathway in cultured smooth muscle cells.
    Nagata T; Kai H; Shibata R; Koga M; Yoshimura A; Imaizumi T
    Arterioscler Thromb Vasc Biol; 2003 Apr; 23(4):588-93. PubMed ID: 12615664
    [TBL] [Abstract][Full Text] [Related]  

  • 16. ERK pathway mediates P2X7 expression and cell death in renal interstitial fibroblasts exposed to necrotic renal epithelial cells.
    Ponnusamy M; Liu N; Gong R; Yan H; Zhuang S
    Am J Physiol Renal Physiol; 2011 Sep; 301(3):F650-9. PubMed ID: 21677150
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Disruption of tissue-type plasminogen activator gene in mice reduces renal interstitial fibrosis in obstructive nephropathy.
    Yang J; Shultz RW; Mars WM; Wegner RE; Li Y; Dai C; Nejak K; Liu Y
    J Clin Invest; 2002 Nov; 110(10):1525-38. PubMed ID: 12438450
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Protein kinase C alpha trigger Ras and Raf-independent MEK/ERK activation for TPA-induced growth inhibition of human hepatoma cell HepG2.
    Wen-Sheng W
    Cancer Lett; 2006 Jul; 239(1):27-35. PubMed ID: 16169661
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The hemopexin domain of matrix metalloproteinase-9 activates cell signaling and promotes migration of schwann cells by binding to low-density lipoprotein receptor-related protein.
    Mantuano E; Inoue G; Li X; Takahashi K; Gaultier A; Gonias SL; Campana WM
    J Neurosci; 2008 Nov; 28(45):11571-82. PubMed ID: 18987193
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Nuclear factor-inducing kinase plays a crucial role in osteopontin-induced MAPK/IkappaBalpha kinase-dependent nuclear factor kappaB-mediated promatrix metalloproteinase-9 activation.
    Rangaswami H; Bulbule A; Kundu GC
    J Biol Chem; 2004 Sep; 279(37):38921-35. PubMed ID: 15247285
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.