BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

278 related articles for article (PubMed ID: 16305230)

  • 1. Cloning, sequencing, analysis, and heterologous expression of the fredericamycin biosynthetic gene cluster from Streptomyces griseus.
    Wendt-Pienkowski E; Huang Y; Zhang J; Li B; Jiang H; Kwon H; Hutchinson CR; Shen B
    J Am Chem Soc; 2005 Nov; 127(47):16442-52. PubMed ID: 16305230
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Identification of fredericamycin E from Streptomyces griseus: Insights into fredericamycin A biosynthesis highlighting carbaspirocycle formation.
    Chen Y; Luo Y; Ju J; Wendt-Pienkowski E; Rajski SR; Shen B
    J Nat Prod; 2008 Mar; 71(3):431-7. PubMed ID: 18232659
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Identification and utility of FdmR1 as a Streptomyces antibiotic regulatory protein activator for fredericamycin production in Streptomyces griseus ATCC 49344 and heterologous hosts.
    Chen Y; Wendt-Pienkowski E; Shen B
    J Bacteriol; 2008 Aug; 190(16):5587-96. PubMed ID: 18556785
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The tallysomycin biosynthetic gene cluster from Streptoalloteichus hindustanus E465-94 ATCC 31158 unveiling new insights into the biosynthesis of the bleomycin family of antitumor antibiotics.
    Tao M; Wang L; Wendt-Pienkowski E; George NP; Galm U; Zhang G; Coughlin JM; Shen B
    Mol Biosyst; 2007 Jan; 3(1):60-74. PubMed ID: 17216057
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Chalcomycin biosynthesis gene cluster from Streptomyces bikiniensis: novel features of an unusual ketolide produced through expression of the chm polyketide synthase in Streptomyces fradiae.
    Ward SL; Hu Z; Schirmer A; Reid R; Revill WP; Reeves CD; Petrakovsky OV; Dong SD; Katz L
    Antimicrob Agents Chemother; 2004 Dec; 48(12):4703-12. PubMed ID: 15561847
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Cloning, sequencing, and functional analysis of the biosynthetic gene cluster of macrolactam antibiotic vicenistatin in Streptomyces halstedii.
    Ogasawara Y; Katayama K; Minami A; Otsuka M; Eguchi T; Kakinuma K
    Chem Biol; 2004 Jan; 11(1):79-86. PubMed ID: 15112997
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Biosynthesis of the antitumor chromomycin A3 in Streptomyces griseus: analysis of the gene cluster and rational design of novel chromomycin analogs.
    Menéndez N; Nur-e-Alam M; Braña AF; Rohr J; Salas JA; Méndez C
    Chem Biol; 2004 Jan; 11(1):21-32. PubMed ID: 15112992
    [TBL] [Abstract][Full Text] [Related]  

  • 8. In vivo investigation of the roles of FdmM and FdmM1 in fredericamycin biosynthesis unveiling a new family of oxygenases.
    Chen Y; Wendt-Pienkoski E; Rajski SR; Shen B
    J Biol Chem; 2009 Sep; 284(37):24735-43. PubMed ID: 19620242
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cloning, sequencing, and characterization of the pradimicin biosynthetic gene cluster of Actinomadura hibisca P157-2.
    Kim BC; Lee JM; Ahn JS; Kim BS
    J Microbiol Biotechnol; 2007 May; 17(5):830-9. PubMed ID: 18051306
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A dedicated phosphopantetheinyl transferase for the fredericamycin polyketide synthase from Streptomyces griseus.
    Huang Y; Wendt-Pienkowski E; Shen B
    J Biol Chem; 2006 Oct; 281(40):29660-8. PubMed ID: 16895912
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Characterization of biosynthetic gene cluster for the production of virginiamycin M, a streptogramin type A antibiotic, in Streptomyces virginiae.
    Pulsawat N; Kitani S; Nihira T
    Gene; 2007 May; 393(1-2):31-42. PubMed ID: 17350183
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Comparative characterization of the lactimidomycin and iso-migrastatin biosynthetic machineries revealing unusual features for acyltransferase-less type I polyketide synthases and providing an opportunity to engineer new analogues.
    Seo JW; Ma M; Kwong T; Ju J; Lim SK; Jiang H; Lohman JR; Yang C; Cleveland J; Zazopoulos E; Farnet CM; Shen B
    Biochemistry; 2014 Dec; 53(49):7854-65. PubMed ID: 25405956
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cloning and elucidation of the FR901464 gene cluster revealing a complex acyltransferase-less polyketide synthase using glycerate as starter units.
    Zhang F; He HY; Tang MC; Tang YM; Zhou Q; Tang GL
    J Am Chem Soc; 2011 Mar; 133(8):2452-62. PubMed ID: 21291275
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Cloning and characterization of the biosynthetic gene cluster of the bacterial RNA polymerase inhibitor tirandamycin from marine-derived Streptomyces sp. SCSIO1666.
    Mo X; Wang Z; Wang B; Ma J; Huang H; Tian X; Zhang S; Zhang C; Ju J
    Biochem Biophys Res Commun; 2011 Mar; 406(3):341-7. PubMed ID: 21329667
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Identification and characterization of the biosynthetic gene cluster of divergolides from Streptomyces sp. W112.
    Li SR; Zhao GS; Sun MW; He HG; Wang HX; Li YY; Lu CH; Shen YM
    Gene; 2014 Jul; 544(1):93-9. PubMed ID: 24768719
    [TBL] [Abstract][Full Text] [Related]  

  • 16. The hedamycin locus implicates a novel aromatic PKS priming mechanism.
    Bililign T; Hyun CG; Williams JS; Czisny AM; Thorson JS
    Chem Biol; 2004 Jul; 11(7):959-69. PubMed ID: 15271354
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Characterization of FdmV as an amide synthetase for fredericamycin A biosynthesis in Streptomyces griseus ATCC 43944.
    Chen Y; Wendt-Pienkowski E; Ju J; Lin S; Rajski SR; Shen B
    J Biol Chem; 2010 Dec; 285(50):38853-60. PubMed ID: 20926388
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Candicidin biosynthesis in Streptomyces griseus.
    Gil JA; Campelo-Diez AB
    Appl Microbiol Biotechnol; 2003 Feb; 60(6):633-42. PubMed ID: 12664141
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Identification of the biosynthetic gene cluster and regulatory cascade for the synergistic antibacterial antibiotics griseoviridin and viridogrisein in Streptomyces griseoviridis.
    Xie Y; Wang B; Liu J; Zhou J; Ma J; Huang H; Ju J
    Chembiochem; 2012 Dec; 13(18):2745-57. PubMed ID: 23161816
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Biosynthesis of the antitumor agent chartreusin involves the oxidative rearrangement of an anthracyclic polyketide.
    Xu Z; Jakobi K; Welzel K; Hertweck C
    Chem Biol; 2005 May; 12(5):579-88. PubMed ID: 15911378
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.