213 related articles for article (PubMed ID: 16307453)
1. Transport of drugs in the kidney by the human organic cation transporter, OCT2 and its genetic variants.
Fujita T; Urban TJ; Leabman MK; Fujita K; Giacomini KM
J Pharm Sci; 2006 Jan; 95(1):25-36. PubMed ID: 16307453
[TBL] [Abstract][Full Text] [Related]
2. Deficiency in the organic cation transporters 1 and 2 (Oct1/Oct2 [Slc22a1/Slc22a2]) in mice abolishes renal secretion of organic cations.
Jonker JW; Wagenaar E; Van Eijl S; Schinkel AH
Mol Cell Biol; 2003 Nov; 23(21):7902-8. PubMed ID: 14560032
[TBL] [Abstract][Full Text] [Related]
3. Functional characterization of the human organic cation transporter 2 variant p.270Ala>Ser.
Zolk O; Solbach TF; König J; Fromm MF
Drug Metab Dispos; 2009 Jun; 37(6):1312-8. PubMed ID: 19251820
[TBL] [Abstract][Full Text] [Related]
4. Vectorial transport of the plant alkaloid berberine by double-transfected cells expressing the human organic cation transporter 1 (OCT1, SLC22A1) and the efflux pump MDR1 P-glycoprotein (ABCB1).
Nies AT; Herrmann E; Brom M; Keppler D
Naunyn Schmiedebergs Arch Pharmacol; 2008 Feb; 376(6):449-61. PubMed ID: 18157518
[TBL] [Abstract][Full Text] [Related]
5. Functional characteristics and membrane localization of rat multispecific organic cation transporters, OCT1 and OCT2, mediating tubular secretion of cationic drugs.
Urakami Y; Okuda M; Masuda S; Saito H; Inui KI
J Pharmacol Exp Ther; 1998 Nov; 287(2):800-5. PubMed ID: 9808712
[TBL] [Abstract][Full Text] [Related]
6. Human multidrug and toxin extrusion 1 (MATE1/SLC47A1) transporter: functional characterization, interaction with OCT2 (SLC22A2), and single nucleotide polymorphisms.
Meyer zu Schwabedissen HE; Verstuyft C; Kroemer HK; Becquemont L; Kim RB
Am J Physiol Renal Physiol; 2010 Apr; 298(4):F997-F1005. PubMed ID: 20053795
[TBL] [Abstract][Full Text] [Related]
7. Kidney-specific expression of human organic cation transporter 2 (OCT2/SLC22A2) is regulated by DNA methylation.
Aoki M; Terada T; Kajiwara M; Ogasawara K; Ikai I; Ogawa O; Katsura T; Inui K
Am J Physiol Renal Physiol; 2008 Jul; 295(1):F165-70. PubMed ID: 18508876
[TBL] [Abstract][Full Text] [Related]
8. Genetic variants of organic cation transporter 2 (OCT2) significantly reduce metformin uptake in oocytes.
Song IS; Shin HJ; Shin JG
Xenobiotica; 2008 Sep; 38(9):1252-62. PubMed ID: 18728938
[TBL] [Abstract][Full Text] [Related]
9. Organic cation transporter OCTs (SLC22) and MATEs (SLC47) in the human kidney.
Motohashi H; Inui K
AAPS J; 2013 Apr; 15(2):581-8. PubMed ID: 23435786
[TBL] [Abstract][Full Text] [Related]
10. Characterization of human organic cation transporter 1 (OCT1/SLC22A1)- and OCT2 (SLC22A2)-mediated transport of 1-(2-methoxyethyl)-2-methyl-4,9-dioxo-3-(pyrazin-2-ylmethyl)- 4,9-dihydro-1H-naphtho[2,3-d]imidazolium bromide (YM155 monobromide), a novel small molecule survivin suppressant.
Minematsu T; Iwai M; Umehara K; Usui T; Kamimura H
Drug Metab Dispos; 2010 Jan; 38(1):1-4. PubMed ID: 19833842
[TBL] [Abstract][Full Text] [Related]
11. Correlation between Apparent Substrate Affinity and OCT2 Transport Turnover.
Severance AC; Sandoval PJ; Wright SH
J Pharmacol Exp Ther; 2017 Sep; 362(3):405-412. PubMed ID: 28615288
[TBL] [Abstract][Full Text] [Related]
12. Renal uptake of substrates for organic anion transporters Oat1 and Oat3 and organic cation transporters Oct1 and Oct2 is altered in rats with adenine-induced chronic renal failure.
Komazawa H; Yamaguchi H; Hidaka K; Ogura J; Kobayashi M; Iseki K
J Pharm Sci; 2013 Mar; 102(3):1086-94. PubMed ID: 23280877
[TBL] [Abstract][Full Text] [Related]
13. Organic cation transporters (OCTs, MATEs), in vitro and in vivo evidence for the importance in drug therapy.
Nies AT; Koepsell H; Damme K; Schwab M
Handb Exp Pharmacol; 2011; (201):105-67. PubMed ID: 21103969
[TBL] [Abstract][Full Text] [Related]
14. Structural determinants of inhibitor interaction with the human organic cation transporter OCT2 (SLC22A2).
Zolk O; Solbach TF; König J; Fromm MF
Naunyn Schmiedebergs Arch Pharmacol; 2009 Apr; 379(4):337-48. PubMed ID: 19002438
[TBL] [Abstract][Full Text] [Related]
15. Functional characteristics and steroid hormone-mediated regulation of an organic cation transporter in Madin-Darby canine kidney cells.
Shu Y; Bello CL; Mangravite LM; Feng B; Giacomini KM
J Pharmacol Exp Ther; 2001 Oct; 299(1):392-8. PubMed ID: 11561104
[TBL] [Abstract][Full Text] [Related]
16. Investigation of the role of organic cation transporter 2 (OCT2) in the renal transport of guanfacine, a selective α2A-adrenoreceptor agonist.
Li X; Sun X; Chen J; Lu Y; Zhang Y; Wang C; Li J; Zhang Q; Zhao D; Chen X
Xenobiotica; 2015 Jan; 45(1):88-94. PubMed ID: 25115365
[TBL] [Abstract][Full Text] [Related]
17. Prediction of clinical drug-drug interactions of veliparib (ABT-888) with human renal transporters (OAT1, OAT3, OCT2, MATE1, and MATE2K).
Kikuchi R; Lao Y; Bow DA; Chiou WJ; Andracki ME; Carr RA; Voorman RL; De Morais SM
J Pharm Sci; 2013 Dec; 102(12):4426-32. PubMed ID: 24122511
[TBL] [Abstract][Full Text] [Related]
18. Organic cation transporter 2 (SLC22A2), a low-affinity and high-capacity choline transporter, is preferentially enriched on synaptic vesicles in cholinergic neurons.
Nakata T; Matsui T; Kobayashi K; Kobayashi Y; Anzai N
Neuroscience; 2013 Nov; 252():212-21. PubMed ID: 23958595
[TBL] [Abstract][Full Text] [Related]
19. Interaction of Cisplatin with the human organic cation transporter 2.
Filipski KK; Loos WJ; Verweij J; Sparreboom A
Clin Cancer Res; 2008 Jun; 14(12):3875-80. PubMed ID: 18559608
[TBL] [Abstract][Full Text] [Related]
20. In vitro interaction of clopidogrel and its hydrolysate with OCT1, OCT2 and OAT1.
Li L; Song F; Tu M; Wang K; Zhao L; Wu X; Zhou H; Xia Z; Jiang H
Int J Pharm; 2014 Apr; 465(1-2):5-10. PubMed ID: 24530383
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
