316 related articles for article (PubMed ID: 16311512)
1. Regulation of the antioncogenic Chk2 kinase by the oncogenic Wip1 phosphatase.
Fujimoto H; Onishi N; Kato N; Takekawa M; Xu XZ; Kosugi A; Kondo T; Imamura M; Oishi I; Yoda A; Minami Y
Cell Death Differ; 2006 Jul; 13(7):1170-80. PubMed ID: 16311512
[TBL] [Abstract][Full Text] [Related]
2. Arsenic trioxide augments Chk2/p53-mediated apoptosis by inhibiting oncogenic Wip1 phosphatase.
Yoda A; Toyoshima K; Watanabe Y; Onishi N; Hazaka Y; Tsukuda Y; Tsukada J; Kondo T; Tanaka Y; Minami Y
J Biol Chem; 2008 Jul; 283(27):18969-79. PubMed ID: 18482988
[TBL] [Abstract][Full Text] [Related]
3. The Wip1 phosphatase (PPM1D) antagonizes activation of the Chk2 tumour suppressor kinase.
Oliva-Trastoy M; Berthonaud V; Chevalier A; Ducrot C; Marsolier-Kergoat MC; Mann C; Leteurtre F
Oncogene; 2007 Mar; 26(10):1449-58. PubMed ID: 16936775
[TBL] [Abstract][Full Text] [Related]
4. Intrinsic kinase activity and SQ/TQ domain of Chk2 kinase as well as N-terminal domain of Wip1 phosphatase are required for regulation of Chk2 by Wip1.
Yoda A; Xu XZ; Onishi N; Toyoshima K; Fujimoto H; Kato N; Oishi I; Kondo T; Minami Y
J Biol Chem; 2006 Aug; 281(34):24847-62. PubMed ID: 16798742
[TBL] [Abstract][Full Text] [Related]
5. A protein phosphatase feedback mechanism regulates the basal phosphorylation of Chk2 kinase in the absence of DNA damage.
Carlessi L; Buscemi G; Fontanella E; Delia D
Biochim Biophys Acta; 2010 Oct; 1803(10):1213-23. PubMed ID: 20599567
[TBL] [Abstract][Full Text] [Related]
6. Increased wild-type p53-induced phosphatase 1 (Wip1 or PPM1D) expression correlated with downregulation of checkpoint kinase 2 in human gastric carcinoma.
Fuku T; Semba S; Yutori H; Yokozaki H
Pathol Int; 2007 Sep; 57(9):566-71. PubMed ID: 17685927
[TBL] [Abstract][Full Text] [Related]
7. The Wip1 Phosphatase acts as a gatekeeper in the p53-Mdm2 autoregulatory loop.
Lu X; Ma O; Nguyen TA; Jones SN; Oren M; Donehower LA
Cancer Cell; 2007 Oct; 12(4):342-54. PubMed ID: 17936559
[TBL] [Abstract][Full Text] [Related]
8. Augmented cancer resistance and DNA damage response phenotypes in PPM1D null mice.
Nannenga B; Lu X; Dumble M; Van Maanen M; Nguyen TA; Sutton R; Kumar TR; Donehower LA
Mol Carcinog; 2006 Aug; 45(8):594-604. PubMed ID: 16652371
[TBL] [Abstract][Full Text] [Related]
9. The estrogen receptor alpha pathway induces oncogenic Wip1 phosphatase gene expression.
Han HS; Yu E; Song JY; Park JY; Jang SJ; Choi J
Mol Cancer Res; 2009 May; 7(5):713-23. PubMed ID: 19435816
[TBL] [Abstract][Full Text] [Related]
10. Protein phosphatase 2A interacts with Chk2 and regulates phosphorylation at Thr-68 after cisplatin treatment of human ovarian cancer cells.
Liang X; Reed E; Yu JJ
Int J Mol Med; 2006 May; 17(5):703-8. PubMed ID: 16596250
[TBL] [Abstract][Full Text] [Related]
11. The Wip1 phosphatase PPM1D dephosphorylates SQ/TQ motifs in checkpoint substrates phosphorylated by PI3K-like kinases.
Yamaguchi H; Durell SR; Chatterjee DK; Anderson CW; Appella E
Biochemistry; 2007 Nov; 46(44):12594-603. PubMed ID: 17939684
[TBL] [Abstract][Full Text] [Related]
12. Wip1 phosphatase modulates ATM-dependent signaling pathways.
Shreeram S; Demidov ON; Hee WK; Yamaguchi H; Onishi N; Kek C; Timofeev ON; Dudgeon C; Fornace AJ; Anderson CW; Minami Y; Appella E; Bulavin DV
Mol Cell; 2006 Sep; 23(5):757-64. PubMed ID: 16949371
[TBL] [Abstract][Full Text] [Related]
13. Fenofibrate antagonizes Chk2 activation by inducing Wip1 expression: implications for cell proliferation and tumorigenesis.
Joe Y; Do MH; Seo E; Kang S; Park HT; Yun J; Lee HJ
Life Sci; 2010 May; 86(19-20):716-21. PubMed ID: 20226795
[TBL] [Abstract][Full Text] [Related]
14. PPM1D dephosphorylates Chk1 and p53 and abrogates cell cycle checkpoints.
Lu X; Nannenga B; Donehower LA
Genes Dev; 2005 May; 19(10):1162-74. PubMed ID: 15870257
[TBL] [Abstract][Full Text] [Related]
15. Reversal of the ATM/ATR-mediated DNA damage response by the oncogenic phosphatase PPM1D.
Lu X; Nguyen TA; Donehower LA
Cell Cycle; 2005 Aug; 4(8):1060-4. PubMed ID: 15970689
[TBL] [Abstract][Full Text] [Related]
16. Overexpression of the wip1 gene abrogates the p38 MAPK/p53/Wip1 pathway and silences p16 expression in human breast cancers.
Yu E; Ahn YS; Jang SJ; Kim MJ; Yoon HS; Gong G; Choi J
Breast Cancer Res Treat; 2007 Mar; 101(3):269-78. PubMed ID: 16897432
[TBL] [Abstract][Full Text] [Related]
17. DNA damage-induced regulatory interplay between DAXX, p53, ATM kinase and Wip1 phosphatase.
Brazina J; Svadlenka J; Macurek L; Andera L; Hodny Z; Bartek J; Hanzlikova H
Cell Cycle; 2015; 14(3):375-87. PubMed ID: 25659035
[TBL] [Abstract][Full Text] [Related]
18. Priming phosphorylation of Chk2 by polo-like kinase 3 (Plk3) mediates its full activation by ATM and a downstream checkpoint in response to DNA damage.
Bahassi el M; Myer DL; McKenney RJ; Hennigan RF; Stambrook PJ
Mutat Res; 2006 Apr; 596(1-2):166-76. PubMed ID: 16481012
[TBL] [Abstract][Full Text] [Related]
19. Regulation of ATM/p53-dependent suppression of myc-induced lymphomas by Wip1 phosphatase.
Shreeram S; Hee WK; Demidov ON; Kek C; Yamaguchi H; Fornace AJ; Anderson CW; Appella E; Bulavin DV
J Exp Med; 2006 Dec; 203(13):2793-9. PubMed ID: 17158963
[TBL] [Abstract][Full Text] [Related]
20. Wip1 phosphatase is associated with chromatin and dephosphorylates gammaH2AX to promote checkpoint inhibition.
Macůrek L; Lindqvist A; Voets O; Kool J; Vos HR; Medema RH
Oncogene; 2010 Apr; 29(15):2281-91. PubMed ID: 20101220
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]