BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

248 related articles for article (PubMed ID: 16314489)

  • 1. Inactivation of NF1 in CNS causes increased glial progenitor proliferation and optic glioma formation.
    Zhu Y; Harada T; Liu L; Lush ME; Guignard F; Harada C; Burns DK; Bajenaru ML; Gutmann DH; Parada LF
    Development; 2005 Dec; 132(24):5577-88. PubMed ID: 16314489
    [TBL] [Abstract][Full Text] [Related]  

  • 2. NG2-cells are not the cell of origin for murine neurofibromatosis-1 (Nf1) optic glioma.
    Solga AC; Gianino SM; Gutmann DH
    Oncogene; 2014 Jan; 33(3):289-99. PubMed ID: 23318450
    [TBL] [Abstract][Full Text] [Related]  

  • 3. NF1 germline mutation differentially dictates optic glioma formation and growth in neurofibromatosis-1.
    Toonen JA; Anastasaki C; Smithson LJ; Gianino SM; Li K; Kesterson RA; Gutmann DH
    Hum Mol Genet; 2016 May; 25(9):1703-13. PubMed ID: 26908603
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The cell of origin dictates the temporal course of neurofibromatosis-1 (Nf1) low-grade glioma formation.
    Solga AC; Toonen JA; Pan Y; Cimino PJ; Ma Y; Castillon GA; Gianino SM; Ellisman MH; Lee DY; Gutmann DH
    Oncotarget; 2017 Jul; 8(29):47206-47215. PubMed ID: 28525381
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Akt- or MEK-mediated mTOR inhibition suppresses Nf1 optic glioma growth.
    Kaul A; Toonen JA; Cimino PJ; Gianino SM; Gutmann DH
    Neuro Oncol; 2015 Jun; 17(6):843-53. PubMed ID: 25534823
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Preclinical cancer therapy in a mouse model of neurofibromatosis-1 optic glioma.
    Hegedus B; Banerjee D; Yeh TH; Rothermich S; Perry A; Rubin JB; Garbow JR; Gutmann DH
    Cancer Res; 2008 Mar; 68(5):1520-8. PubMed ID: 18316617
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Neurofibromatosis Type 1 and tumorigenesis: molecular mechanisms and therapeutic implications.
    Gottfried ON; Viskochil DH; Couldwell WT
    Neurosurg Focus; 2010 Jan; 28(1):E8. PubMed ID: 20043723
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Optic nerve glioma in mice requires astrocyte Nf1 gene inactivation and Nf1 brain heterozygosity.
    Bajenaru ML; Hernandez MR; Perry A; Zhu Y; Parada LF; Garbow JR; Gutmann DH
    Cancer Res; 2003 Dec; 63(24):8573-7. PubMed ID: 14695164
    [TBL] [Abstract][Full Text] [Related]  

  • 9. NF1 mutation drives neuronal activity-dependent initiation of optic glioma.
    Pan Y; Hysinger JD; Barron T; Schindler NF; Cobb O; Guo X; Yalçın B; Anastasaki C; Mulinyawe SB; Ponnuswami A; Scheaffer S; Ma Y; Chang KC; Xia X; Toonen JA; Lennon JJ; Gibson EM; Huguenard JR; Liau LM; Goldberg JL; Monje M; Gutmann DH
    Nature; 2021 Jun; 594(7862):277-282. PubMed ID: 34040258
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Spatiotemporal differences in CXCL12 expression and cyclic AMP underlie the unique pattern of optic glioma growth in neurofibromatosis type 1.
    Warrington NM; Woerner BM; Daginakatte GC; Dasgupta B; Perry A; Gutmann DH; Rubin JB
    Cancer Res; 2007 Sep; 67(18):8588-95. PubMed ID: 17875698
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Treatment during a developmental window prevents NF1-associated optic pathway gliomas by targeting Erk-dependent migrating glial progenitors.
    Jecrois ES; Zheng W; Bornhorst M; Li Y; Treisman DM; Muguyo D; Huynh S; Andrew SF; Wang Y; Jiang J; Pierce BR; Mao H; Krause MK; Friend A; Nadal-Nicolas F; Stasheff SF; Li W; Zong H; Packer RJ; Zhu Y
    Dev Cell; 2021 Oct; 56(20):2871-2885.e6. PubMed ID: 34428430
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mice with GFAP-targeted loss of neurofibromin demonstrate increased axonal MET expression with aging.
    Su W; Xing R; Guha A; Gutmann DH; Sherman LS
    Glia; 2007 May; 55(7):723-33. PubMed ID: 17348023
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The impact of coexisting genetic mutations on murine optic glioma biology.
    Kaul A; Toonen JA; Gianino SM; Gutmann DH
    Neuro Oncol; 2015 May; 17(5):670-7. PubMed ID: 25246427
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Cerebrospinal fluid proteomic analysis reveals dysregulation of methionine aminopeptidase-2 expression in human and mouse neurofibromatosis 1-associated glioma.
    Dasgupta B; Yi Y; Hegedus B; Weber JD; Gutmann DH
    Cancer Res; 2005 Nov; 65(21):9843-50. PubMed ID: 16267007
    [TBL] [Abstract][Full Text] [Related]  

  • 15. RNA Sequencing of Tumor-Associated Microglia Reveals Ccl5 as a Stromal Chemokine Critical for Neurofibromatosis-1 Glioma Growth.
    Solga AC; Pong WW; Kim KY; Cimino PJ; Toonen JA; Walker J; Wylie T; Magrini V; Griffith M; Griffith OL; Ly A; Ellisman MH; Mardis ER; Gutmann DH
    Neoplasia; 2015 Oct; 17(10):776-88. PubMed ID: 26585233
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Neurofibromin regulates neural stem cell proliferation, survival, and astroglial differentiation in vitro and in vivo.
    Dasgupta B; Gutmann DH
    J Neurosci; 2005 Jun; 25(23):5584-94. PubMed ID: 15944386
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Neurofibromatosis-1 (Nf1) heterozygous brain microglia elaborate paracrine factors that promote Nf1-deficient astrocyte and glioma growth.
    Daginakatte GC; Gutmann DH
    Hum Mol Genet; 2007 May; 16(9):1098-112. PubMed ID: 17400655
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Ultrastructural characterization of the optic pathway in a mouse model of neurofibromatosis-1 optic glioma.
    Kim KY; Ju WK; Hegedus B; Gutmann DH; Ellisman MH
    Neuroscience; 2010 Sep; 170(1):178-88. PubMed ID: 20600672
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Insights into optic pathway glioma vision loss from mouse models of neurofibromatosis type 1.
    Freret ME; Gutmann DH
    J Neurosci Res; 2019 Jan; 97(1):45-56. PubMed ID: 29704429
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Increased c-Jun-NH2-kinase signaling in neurofibromatosis-1 heterozygous microglia drives microglia activation and promotes optic glioma proliferation.
    Daginakatte GC; Gianino SM; Zhao NW; Parsadanian AS; Gutmann DH
    Cancer Res; 2008 Dec; 68(24):10358-66. PubMed ID: 19074905
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.