These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

163 related articles for article (PubMed ID: 16325416)

  • 1. Polyglutamine and polyalanine expansions in ataxin7 result in different types of aggregation and levels of toxicity.
    Latouche M; Fragner P; Martin E; El Hachimi KH; Zander C; Sittler A; Ruberg M; Brice A; Stevanin G
    Mol Cell Neurosci; 2006 Mar; 31(3):438-45. PubMed ID: 16325416
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Neuronal dysfunction in a polyglutamine disease model occurs in the absence of ubiquitin-proteasome system impairment and inversely correlates with the degree of nuclear inclusion formation.
    Bowman AB; Yoo SY; Dantuma NP; Zoghbi HY
    Hum Mol Genet; 2005 Mar; 14(5):679-91. PubMed ID: 15661755
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Amyloid precursor-like protein 2 cleavage contributes to neuronal intranuclear inclusions and cytotoxicity in spinocerebellar ataxia-7 (SCA7).
    Takahashi-Fujigasaki J; Breidert T; Fujigasaki H; Duyckaerts C; Camonis JH; Brice A; Lebre AS
    Neurobiol Dis; 2011 Jan; 41(1):33-42. PubMed ID: 20732423
    [TBL] [Abstract][Full Text] [Related]  

  • 4. SUMOylation attenuates the aggregation propensity and cellular toxicity of the polyglutamine expanded ataxin-7.
    Janer A; Werner A; Takahashi-Fujigasaki J; Daret A; Fujigasaki H; Takada K; Duyckaerts C; Brice A; Dejean A; Sittler A
    Hum Mol Genet; 2010 Jan; 19(1):181-95. PubMed ID: 19843541
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Molecular chaperones as modulators of polyglutamine protein aggregation and toxicity.
    Sakahira H; Breuer P; Hayer-Hartl MK; Hartl FU
    Proc Natl Acad Sci U S A; 2002 Dec; 99 Suppl 4(Suppl 4):16412-8. PubMed ID: 12189209
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Ataxin-7 aggregation and ubiquitination in infantile SCA7 with 180 CAG repeats.
    Ansorge O; Giunti P; Michalik A; Van Broeckhoven C; Harding B; Wood N; Scaravilli F
    Ann Neurol; 2004 Sep; 56(3):448-52. PubMed ID: 15349877
    [TBL] [Abstract][Full Text] [Related]  

  • 7. CHIP protects from the neurotoxicity of expanded and wild-type ataxin-1 and promotes their ubiquitination and degradation.
    Al-Ramahi I; Lam YC; Chen HK; de Gouyon B; Zhang M; Pérez AM; Branco J; de Haro M; Patterson C; Zoghbi HY; Botas J
    J Biol Chem; 2006 Sep; 281(36):26714-24. PubMed ID: 16831871
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Intranuclear immunolocalization of 14-3-3 protein isoforms in brains with spinocerebellar ataxia type 1.
    Umahara T; Uchihara T; Yagishita S; Nakamura A; Tsuchiya K; Iwamoto T
    Neurosci Lett; 2007 Mar; 414(2):130-5. PubMed ID: 17224237
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Neuronal toxicity of expanded polyglutamine depends on intracellular distribution in addition to the expression level.
    Satoh M; Shimada A; Kawamura N; Chiba Y; Yoshikawa K; Ishii S; Furukawa A; Kumagai N; Hosokawa M
    Neuropathology; 2008 Oct; 28(5):485-96. PubMed ID: 18384512
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Nanoparticle-induced cell culture models for degenerative protein aggregation diseases.
    Chen M; von Mikecz A
    Inhal Toxicol; 2009 Jul; 21 Suppl 1():110-4. PubMed ID: 19558242
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Mimicking proteasomal release of polyglutamine peptides initiates aggregation and toxicity.
    Raspe M; Gillis J; Krol H; Krom S; Bosch K; van Veen H; Reits E
    J Cell Sci; 2009 Sep; 122(Pt 18):3262-71. PubMed ID: 19690053
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Role of polyunsaturated fatty acids for misfolding protein aggregations: implication for neurodegenerative diseases.
    Kim YJ; Takahashi R
    Ann N Y Acad Sci; 2006 Nov; 1086():11-20. PubMed ID: 17185502
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A conditional pan-neuronal Drosophila model of spinocerebellar ataxia 7 with a reversible adult phenotype suitable for identifying modifier genes.
    Latouche M; Lasbleiz C; Martin E; Monnier V; Debeir T; Mouatt-Prigent A; Muriel MP; Morel L; Ruberg M; Brice A; Stevanin G; Tricoire H
    J Neurosci; 2007 Mar; 27(10):2483-92. PubMed ID: 17344386
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Interferon β induces clearance of mutant ataxin 7 and improves locomotion in SCA7 knock-in mice.
    Chort A; Alves S; Marinello M; Dufresnois B; Dornbierer JG; Tesson C; Latouche M; Baker DP; Barkats M; El Hachimi KH; Ruberg M; Janer A; Stevanin G; Brice A; Sittler A
    Brain; 2013 Jun; 136(Pt 6):1732-45. PubMed ID: 23518714
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Decreased expression of Hsp27 and Hsp70 in transformed lymphoblastoid cells from patients with spinocerebellar ataxia type 7.
    Tsai HF; Lin SJ; Li C; Hsieh M
    Biochem Biophys Res Commun; 2005 Sep; 334(4):1279-86. PubMed ID: 16039988
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Analyzing the aggregation of polyglutamine-expansion proteins and its modulation by molecular chaperones.
    Kubota H; Kitamura A; Nagata K
    Methods; 2011 Mar; 53(3):267-74. PubMed ID: 21195182
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Neuropathological staging of spinocerebellar ataxia type 2 by semiquantitative 1C2-positive neuron typing. Nuclear translocation of cytoplasmic 1C2 underlies disease progression of spinocerebellar ataxia type 2.
    Koyano S; Yagishita S; Kuroiwa Y; Tanaka F; Uchihara T
    Brain Pathol; 2014 Nov; 24(6):599-606. PubMed ID: 24674145
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Familial frontotemporal dementia with neuronal intranuclear inclusions is not a polyglutamine expansion disease.
    Mackenzie IR; Butland SL; Devon RS; Dwosh E; Feldman H; Lindholm C; Neal SJ; Ouellette BF; Leavitt BR
    BMC Neurol; 2006 Aug; 6():32. PubMed ID: 16945149
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Hsp70 and Hsp40 chaperones do not modulate retinal phenotype in SCA7 mice.
    Helmlinger D; Bonnet J; Mandel JL; Trottier Y; Devys D
    J Biol Chem; 2004 Dec; 279(53):55969-77. PubMed ID: 15494410
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Similarities between spinocerebellar ataxia type 7 (SCA7) cell models and human brain: proteins recruited in inclusions and activation of caspase-3.
    Zander C; Takahashi J; El Hachimi KH; Fujigasaki H; Albanese V; Lebre AS; Stevanin G; Duyckaerts C; Brice A
    Hum Mol Genet; 2001 Oct; 10(22):2569-79. PubMed ID: 11709544
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.