159 related articles for article (PubMed ID: 16327215)
1. Cell-cycle-dependent pharmacology of methotrexate in HL-60.
Yamauchi A; Ichimiya T; Inoue K; Taguchi Y; Matsunaga N; Koyanagi S; Fukagawa T; Aramaki H; Higuchi S; Ohdo S
J Pharmacol Sci; 2005 Dec; 99(4):335-41. PubMed ID: 16327215
[TBL] [Abstract][Full Text] [Related]
2. Dihydrofolate reductase binding and cellular uptake of nonpolyglutamatable antifolates: correlates of cytotoxicity toward methotrexate-sensitive and -resistant human head and neck squamous carcinoma cells.
Chen G; Wright JE; Rosowsky A
Mol Pharmacol; 1995 Oct; 48(4):758-65. PubMed ID: 7476904
[TBL] [Abstract][Full Text] [Related]
3. Resistance mechanisms to methotrexate in tumors.
Bertino JR; Göker E; Gorlick R; Li WW; Banerjee D
Stem Cells; 1996 Jan; 14(1):5-9. PubMed ID: 8820944
[TBL] [Abstract][Full Text] [Related]
4. Drug-resistant dihydrofolate reductases: generation, expression and therapeutic application.
McIvor RS
Bone Marrow Transplant; 1996 Dec; 18 Suppl 3():S50-4. PubMed ID: 8971409
[TBL] [Abstract][Full Text] [Related]
5. Dihydrofolate Reductase and Thymidylate Synthase Transgenes Resistant to Methotrexate Interact to Permit Novel Transgene Regulation.
Rushworth D; Mathews A; Alpert A; Cooper LJ
J Biol Chem; 2015 Sep; 290(38):22970-6. PubMed ID: 26242737
[TBL] [Abstract][Full Text] [Related]
6. Much more than you expected: The non-DHFR-mediated effects of methotrexate.
Sramek M; Neradil J; Veselska R
Biochim Biophys Acta Gen Subj; 2017 Mar; 1861(3):499-503. PubMed ID: 27993660
[TBL] [Abstract][Full Text] [Related]
7. [Primary study on establishment of namalwa 12/MTX resistant cell strain and its mechanism].
Chen J; Gu LJ; Ying DM; Shen M; Wu HJ
Ai Zheng; 2002 Dec; 21(12):1335-40. PubMed ID: 12520743
[TBL] [Abstract][Full Text] [Related]
8. Selection for methotrexate resistance in mammalian cells bearing a Drosophila dihydrofolate reductase transgene: Methotrexate resistance in transgenic mammalian cells.
Affleck JG; Nowickyj SM; Walker VK
Cell Biol Toxicol; 2010 Apr; 26(2):117-26. PubMed ID: 19337845
[TBL] [Abstract][Full Text] [Related]
9. Molecular mechanisms of resistance to antifolates, a review.
Banerjee D; Ercikan-Abali E; Waltham M; Schnieders B; Hochhauser D; Li WW; Fan J; Gorlick R; Goker E; Bertino JR
Acta Biochim Pol; 1995; 42(4):457-64. PubMed ID: 8852336
[TBL] [Abstract][Full Text] [Related]
10. Methotrexate-based PROTACs as DHFR-specific chemical probes.
Rana S; Dranchak P; Dahlin JL; Lamy L; Li W; Oliphant E; Shrimp JH; Rajacharya GH; Tharakan R; Holland DO; Whitten AS; Wilson KM; Singh PK; Durum SK; Tao D; Rai G; Inglese J
Cell Chem Biol; 2024 Feb; 31(2):221-233.e14. PubMed ID: 37875111
[TBL] [Abstract][Full Text] [Related]
11. Chronotoxicity of methotrexate in mice and its relation to circadian rhythm of DNA synthesis and pharmacokinetics.
Ohdo S; Inoue K; Yukawa E; Higuchi S; Nakano S; Ogawa N
Jpn J Pharmacol; 1997 Nov; 75(3):283-90. PubMed ID: 9434260
[TBL] [Abstract][Full Text] [Related]
12. Evolution of drug resistance in CCRF-CEM human leukemia cells selected by intermittent methotrexate exposure.
McGuire JJ; Haile WH; Russell CA; Galvin JM; Shane B
Oncol Res; 1995; 7(10-11):535-43. PubMed ID: 8866666
[TBL] [Abstract][Full Text] [Related]
13. Expression of variant dihydrofolate reductase with decreased binding affinity to antifolates in MOLT-3 human leukemia cell lines resistant to trimetrexate.
Miyachi H; Takemura Y; Kobayashi H; Ando Y
Cancer Lett; 1995 Jan; 88(1):93-9. PubMed ID: 7850779
[TBL] [Abstract][Full Text] [Related]
14. Changes in enzyme activity and expression of DHFR of Toxoplasma gondii by antifolates.
Baek EJ; Nam HW
Korean J Parasitol; 1998 Sep; 36(3):191-8. PubMed ID: 9755590
[TBL] [Abstract][Full Text] [Related]
15. Biochemical factors in the selectivity of leucovorin rescue: selective inhibition of leucovorin reactivation of dihydrofolate reductase and leucovorin utilization in purine and pyrimidine biosynthesis by methotrexate and dihydrofolate polyglutamates.
Goldman ID; Matherly LH
NCI Monogr; 1987; (5):17-26. PubMed ID: 2448654
[TBL] [Abstract][Full Text] [Related]
16. Increased dihydrofolate reductase activity in methotrexate-resistant human promyelocytic-leukaemia (HL-60) cells. Lack of correlation between increased activity and overproduction.
Dedhar S; Hartley D; Goldie JH
Biochem J; 1985 Feb; 225(3):609-17. PubMed ID: 3856428
[TBL] [Abstract][Full Text] [Related]
17. Biological activity and intracellular metabolism of ZD1694 in human leukemia cell lines with different resistance mechanisms to antifolate drugs.
Takemura Y; Kobayashi H; Miyachi H; Gibson W; Kimbell R; Jackman AL
Jpn J Cancer Res; 1996 Jul; 87(7):773-80. PubMed ID: 8698629
[TBL] [Abstract][Full Text] [Related]
18. Investigations on the mechanisms of methotrexate resistance in a cisplatin-resistant L1210 murine leukemia cell subline.
Wroblewski DH; Bhushan A; Xuan Y; Brinton BT; Tritton TR; Hacker MP
Cancer Chemother Pharmacol; 1996; 37(4):337-42. PubMed ID: 8548879
[TBL] [Abstract][Full Text] [Related]
19. Novel aspects of resistance to drugs targeted to dihydrofolate reductase and thymidylate synthase.
Banerjee D; Mayer-Kuckuk P; Capiaux G; Budak-Alpdogan T; Gorlick R; Bertino JR
Biochim Biophys Acta; 2002 Jul; 1587(2-3):164-73. PubMed ID: 12084458
[TBL] [Abstract][Full Text] [Related]
20. Lipophilic methotrexate conjugates with antitumor activity.
Pignatello R; Spampinato G; Sorrenti V; Di Giacomo C; Vicari L; McGuire JJ; Russell CA; Puglisi G; Toth I
Eur J Pharm Sci; 2000 May; 10(3):237-45. PubMed ID: 10767601
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
