BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

145 related articles for article (PubMed ID: 16327895)

  • 1. The effects of substrate orientation on the mechanism of a phosphotriesterase.
    Jackson CJ; Liu JW; Coote ML; Ollis DL
    Org Biomol Chem; 2005 Dec; 3(24):4343-50. PubMed ID: 16327895
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Theoretical study of the phosphotriesterase reaction mechanism.
    Chen SL; Fang WH; Himo F
    J Phys Chem B; 2007 Feb; 111(6):1253-5. PubMed ID: 17253743
    [TBL] [Abstract][Full Text] [Related]  

  • 3. In crystallo capture of a Michaelis complex and product-binding modes of a bacterial phosphotriesterase.
    Jackson CJ; Foo JL; Kim HK; Carr PD; Liu JW; Salem G; Ollis DL
    J Mol Biol; 2008 Feb; 375(5):1189-96. PubMed ID: 18082180
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Resolution of chiral phosphate, phosphonate, and phosphinate esters by an enantioselective enzyme library.
    Nowlan C; Li Y; Hermann JC; Evans T; Carpenter J; Ghanem E; Shoichet BK; Raushel FM
    J Am Chem Soc; 2006 Dec; 128(49):15892-902. PubMed ID: 17147402
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Enhanced degradation of chemical warfare agents through molecular engineering of the phosphotriesterase active site.
    Hill CM; Li WS; Thoden JB; Holden HM; Raushel FM
    J Am Chem Soc; 2003 Jul; 125(30):8990-1. PubMed ID: 15369336
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The reaction mechanism of paraoxon hydrolysis by phosphotriesterase from combined QM/MM simulations.
    Wong KY; Gao J
    Biochemistry; 2007 Nov; 46(46):13352-69. PubMed ID: 17966992
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Protonation of the binuclear metal center within the active site of phosphotriesterase.
    Samples CR; Howard T; Raushel FM; DeRose VJ
    Biochemistry; 2005 Aug; 44(33):11005-13. PubMed ID: 16101284
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Detoxification of organophosphate nerve agents by bacterial phosphotriesterase.
    Ghanem E; Raushel FM
    Toxicol Appl Pharmacol; 2005 Sep; 207(2 Suppl):459-70. PubMed ID: 15982683
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mutational and structural studies of the diisopropylfluorophosphatase from Loligo vulgaris shed new light on the catalytic mechanism of the enzyme.
    Katsemi V; Lücke C; Koepke J; Löhr F; Maurer S; Fritzsch G; Rüterjans H
    Biochemistry; 2005 Jun; 44(25):9022-33. PubMed ID: 15966726
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Structural and functional models of the active site of zinc phosphotriesterase.
    Carlsson H; Haukka M; Nordlander E
    Inorg Chem; 2004 Sep; 43(18):5681-7. PubMed ID: 15332820
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The structure of an enzyme-product complex reveals the critical role of a terminal hydroxide nucleophile in the bacterial phosphotriesterase mechanism.
    Jackson C; Kim HK; Carr PD; Liu JW; Ollis DL
    Biochim Biophys Acta; 2005 Aug; 1752(1):56-64. PubMed ID: 16054447
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structure-based and random mutagenesis approaches increase the organophosphate-degrading activity of a phosphotriesterase homologue from Deinococcus radiodurans.
    Hawwa R; Larsen SD; Ratia K; Mesecar AD
    J Mol Biol; 2009 Oct; 393(1):36-57. PubMed ID: 19631223
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Binding of a designed substrate analogue to diisopropyl fluorophosphatase: implications for the phosphotriesterase mechanism.
    Blum MM; Löhr F; Richardt A; Rüterjans H; Chen JC
    J Am Chem Soc; 2006 Oct; 128(39):12750-7. PubMed ID: 17002369
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Phosphate-bound structure of an organophosphate-degrading enzyme from Agrobacterium radiobacter.
    Ely F; Pedroso MM; Gahan LR; Ollis DL; Guddat LW; Schenk G
    J Inorg Biochem; 2012 Jan; 106(1):19-22. PubMed ID: 22112835
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Predicting substrates by docking high-energy intermediates to enzyme structures.
    Hermann JC; Ghanem E; Li Y; Raushel FM; Irwin JJ; Shoichet BK
    J Am Chem Soc; 2006 Dec; 128(49):15882-91. PubMed ID: 17147401
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Increased expression of a bacterial phosphotriesterase in Escherichia coli through directed evolution.
    McLoughlin SY; Jackson C; Liu JW; Ollis D
    Protein Expr Purif; 2005 Jun; 41(2):433-40. PubMed ID: 15866732
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Evolution in the amidohydrolase superfamily: substrate-assisted gain of function in the E183K mutant of a phosphotriesterase-like metal-carboxylesterase.
    Mandrich L; Manco G
    Biochemistry; 2009 Jun; 48(24):5602-12. PubMed ID: 19438255
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inhibitory potency against human acetylcholinesterase and enzymatic hydrolysis of fluorogenic nerve agent mimics by human paraoxonase 1 and squid diisopropyl fluorophosphatase.
    Blum MM; Timperley CM; Williams GR; Thiermann H; Worek F
    Biochemistry; 2008 May; 47(18):5216-24. PubMed ID: 18396898
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Control of stereoselectivity in phosphotriesterase.
    Hong SB; Raushel FM
    Methods Enzymol; 2004; 388():256-66. PubMed ID: 15289077
    [No Abstract]   [Full Text] [Related]  

  • 20. The electrostatic driving force for nucleophilic catalysis in L-arginine deiminase: a combined experimental and theoretical study.
    Li L; Li Z; Wang C; Xu D; Mariano PS; Guo H; Dunaway-Mariano D
    Biochemistry; 2008 Apr; 47(16):4721-32. PubMed ID: 18366187
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.