BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

151 related articles for article (PubMed ID: 16327993)

  • 1. Antitumor triptycene analogs induce a rapid collapse of mitochondrial transmembrane potential in HL-60 cells and isolated mitochondria.
    Wang Y; Perchellet EM; Ward MM; Lou K; Zhao H; Battina SK; Wiredu B; Hua DH; Perchellet JP
    Int J Oncol; 2006 Jan; 28(1):161-72. PubMed ID: 16327993
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Rapid collapse of mitochondrial transmembrane potential in HL-60 cells and isolated mitochondria treated with anti-tumor 1,4-anthracenediones.
    Wang Y; Perchellet EM; Ward MM; Lou K; Hua DH; Perchellet JP
    Anticancer Drugs; 2005 Oct; 16(9):953-67. PubMed ID: 16162972
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Antitumor triptycene analogs directly interact with isolated mitochondria to rapidly trigger markers of permeability transition.
    Perchellet EM; Wang Y; Lou K; Zhao H; Battina SK; Hua DH; Perchellet JP
    Anticancer Res; 2007; 27(5A):3259-71. PubMed ID: 17970069
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Antitumor triptycene bisquinones induce a caspase-independent release of mitochondrial cytochrome c and a caspase-2-mediated activation of initiator caspase-8 and -9 in HL-60 cells by a mechanism which does not involve Fas signaling.
    Perchellet EM; Wang Y; Weber RL; Lou K; Hua DH; Perchellet JP
    Anticancer Drugs; 2004 Nov; 15(10):929-46. PubMed ID: 15514562
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Novel substituted 1,4-anthracenediones with antitumor activity directly induce permeability transition in isolated mitochondria.
    Perchellet EM; Wang Y; Lou K; Zhao H; Battina SK; Hua DH; Perchellet JP
    Int J Oncol; 2007 Nov; 31(5):1231-41. PubMed ID: 17912452
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthetic 1,4-anthracenedione analogs induce cytochrome c release, caspase-9, -3, and -8 activities, poly(ADP-ribose) polymerase-1 cleavage and internucleosomal DNA fragmentation in HL-60 cells by a mechanism which involves caspase-2 activation but not Fas signaling.
    Perchellet EM; Wang Y; Weber RL; Sperfslage BJ; Lou K; Crossland J; Hua DH; Perchellet JP
    Biochem Pharmacol; 2004 Feb; 67(3):523-37. PubMed ID: 15037204
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Collapse of the inner mitochondrial transmembrane potential is not required for apoptosis of HL60 cells.
    Finucane DM; Waterhouse NJ; Amarante-Mendes GP; Cotter TG; Green DR
    Exp Cell Res; 1999 Aug; 251(1):166-74. PubMed ID: 10438582
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Induction of poly(ADP-ribose) polymerase-1 cleavage by antitumor triptycene bisquinones in wild-type and daunorubicin-resistant HL-60 cell lines.
    Wang Y; Perchellet EM; Tamura M; Hua DH; Perchellet JP
    Cancer Lett; 2002 Dec; 188(1-2):73-83. PubMed ID: 12406551
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Triptycenes: a novel synthetic class of bifunctional anticancer drugs that inhibit nucleoside transport, induce DNA cleavage and decrease the viability of leukemic cells in the nanomolar range in vitro.
    Perchellet EM; Magill MJ; Huang X; Brantis CE; Hua DH; Perchellet JP
    Anticancer Drugs; 1999 Sep; 10(8):749-66. PubMed ID: 10573208
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Vanadium compounds induced mitochondria permeability transition pore (PTP) opening related to oxidative stress.
    Zhao Y; Ye L; Liu H; Xia Q; Zhang Y; Yang X; Wang K
    J Inorg Biochem; 2010 Apr; 104(4):371-8. PubMed ID: 20015552
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A synthetic triptycene bisquinone, which blocks nucleoside transport and induces DNA fragmentation, retains its cytotoxic efficacy in daunorubicin-resistant HL-60 cell lines.
    Wang B; Wu M; Perchellet EM; McIlvain CJ; Sperfslage BJ; Huang X; Tamura M; Stephany HA; Hua DH; Perchellet JP
    Int J Oncol; 2001 Dec; 19(6):1169-78. PubMed ID: 11713586
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mitochondrial permeability transition and swelling can occur reversibly without inducing cell death in intact human cells.
    Minamikawa T; Williams DA; Bowser DN; Nagley P
    Exp Cell Res; 1999 Jan; 246(1):26-37. PubMed ID: 9882512
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Inhibition of glutamate-induced mitochondrial depolarization by tamoxifen in cultured neurons.
    Hoyt KR; McLaughlin BA; Higgins DS; Reynolds IJ
    J Pharmacol Exp Ther; 2000 May; 293(2):480-6. PubMed ID: 10773018
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Among substituted 9,10-dihydro-9,10-[1,2]benzenoanthracene-1,4,5,8-tetraones, the lead antitumor triptycene bisquinone TT24 blocks nucleoside transport, induces apoptotic DNA fragmentation and decreases the viability of L1210 leukemic cells in the nanomolar range of daunorubicin in vitro.
    Perchellet EM; Sperfslage BJ; Wang Y; Huang X; Tamura M; Hua DH; Perchellet JP
    Anticancer Drugs; 2002 Jul; 13(6):567-81. PubMed ID: 12172502
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Calcineurin-independent inhibition of mitochondrial Ca2+ uptake by cyclosporin A.
    Montero M; Lobatón CD; Gutierrez-Fernández S; Moreno A; Alvarez J
    Br J Pharmacol; 2004 Jan; 141(2):263-8. PubMed ID: 14691054
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Estradiol attenuates mitochondrial depolarization in polyol-stressed lens epithelial cells.
    Flynn JM; Cammarata PR
    Mol Vis; 2006 Apr; 12():271-82. PubMed ID: 16617294
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Genistein induces apoptosis of RPE-J cells by opening mitochondrial PTP.
    Yoon HS; Moon SC; Kim ND; Park BS; Jeong MH; Yoo YH
    Biochem Biophys Res Commun; 2000 Sep; 276(1):151-6. PubMed ID: 11006098
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mitochondrial free [Ca2+] levels and the permeability transition.
    Vay L; Hernández-SanMiguel E; Lobatón CD; Moreno A; Montero M; Alvarez J
    Cell Calcium; 2009 Mar; 45(3):243-50. PubMed ID: 19100620
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Permeability transition pore regulates both mitochondrial membrane potential and agonist-evoked Ca2+ signals in oligodendrocyte progenitors.
    Smaili SS; Russell JT
    Cell Calcium; 1999; 26(3-4):121-30. PubMed ID: 10598276
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Head and neck cancer cell lines are resistant to mitochondrial-depolarization-induced apoptosis.
    Zhao M; Mydlarz WK; Zhou S; Califano J
    ORL J Otorhinolaryngol Relat Spec; 2008; 70(4):257-63. PubMed ID: 18483464
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.