124 related articles for article (PubMed ID: 16336273)
1. Structure of the substrate complex of thymidine kinase from Ureaplasma urealyticum and investigations of possible drug targets for the enzyme.
Kosinska U; Carnrot C; Eriksson S; Wang L; Eklund H
FEBS J; 2005 Dec; 272(24):6365-72. PubMed ID: 16336273
[TBL] [Abstract][Full Text] [Related]
2. Molecular characterization of thymidine kinase from Ureaplasma urealyticum: nucleoside analogues as potent inhibitors of mycoplasma growth.
Carnrot C; Wehelie R; Eriksson S; Bölske G; Wang L
Mol Microbiol; 2003 Nov; 50(3):771-80. PubMed ID: 14617140
[TBL] [Abstract][Full Text] [Related]
3. Structural studies of thymidine kinases from Bacillus anthracis and Bacillus cereus provide insights into quaternary structure and conformational changes upon substrate binding.
Kosinska U; Carnrot C; Sandrini MP; Clausen AR; Wang L; Piskur J; Eriksson S; Eklund H
FEBS J; 2007 Feb; 274(3):727-37. PubMed ID: 17288553
[TBL] [Abstract][Full Text] [Related]
4. Structures of thymidine kinase 1 of human and mycoplasmic origin.
Welin M; Kosinska U; Mikkelsen NE; Carnrot C; Zhu C; Wang L; Eriksson S; Munch-Petersen B; Eklund H
Proc Natl Acad Sci U S A; 2004 Dec; 101(52):17970-5. PubMed ID: 15611477
[TBL] [Abstract][Full Text] [Related]
5. Structure of a type II thymidine kinase with bound dTTP.
Birringer MS; Claus MT; Folkers G; Kloer DP; Schulz GE; Scapozza L
FEBS Lett; 2005 Feb; 579(6):1376-82. PubMed ID: 15733844
[TBL] [Abstract][Full Text] [Related]
6. Structural basis for feedback inhibition of the deoxyribonucleoside salvage pathway: studies of the Drosophila deoxyribonucleoside kinase.
Mikkelsen NE; Johansson K; Karlsson A; Knecht W; Andersen G; Piskur J; Munch-Petersen B; Eklund H
Biochemistry; 2003 May; 42(19):5706-12. PubMed ID: 12741827
[TBL] [Abstract][Full Text] [Related]
7. Understanding the binding of 5-substituted 2'-deoxyuridine substrates to thymidine kinase of herpes simplex virus type-1.
De Winter H; Herdewijn P
J Med Chem; 1996 Nov; 39(24):4727-37. PubMed ID: 8941385
[TBL] [Abstract][Full Text] [Related]
8. 3'-[4-Aryl-(1,2,3-triazol-1-yl)]-3'-deoxythymidine analogues as potent and selective inhibitors of human mitochondrial thymidine kinase.
Van Poecke S; Negri A; Gago F; Van Daele I; Solaroli N; Karlsson A; Balzarini J; Van Calenbergh S
J Med Chem; 2010 Apr; 53(7):2902-12. PubMed ID: 20218622
[TBL] [Abstract][Full Text] [Related]
9. N1-substituted thymine derivatives as mitochondrial thymidine kinase (TK-2) inhibitors.
Hernandez AI; Familiar O; Negri A; Rodríguez-Barrios F; Gago F; Karlsson A; Camarasa MJ; Balzarini J; Pérez-Pérez MJ
J Med Chem; 2006 Dec; 49(26):7766-73. PubMed ID: 17181158
[TBL] [Abstract][Full Text] [Related]
10. Enzyme regulatory site-directed drugs. MOdulation of thymidine triphosphate inhibition of thymidine kinase by 5'-amino-5'-deoxythymidine.
Fischer PH; Baxter D
Mol Pharmacol; 1982 Sep; 22(2):231-4. PubMed ID: 7144727
[TBL] [Abstract][Full Text] [Related]
11. Structure of vaccinia virus thymidine kinase in complex with dTTP: insights for drug design.
El Omari K; Solaroli N; Karlsson A; Balzarini J; Stammers DK
BMC Struct Biol; 2006 Oct; 6():22. PubMed ID: 17062140
[TBL] [Abstract][Full Text] [Related]
12. Reversible tetramerization of human TK1 to the high catalytic efficient form is induced by pyrophosphate, in addition to tripolyphosphates, or high enzyme concentration.
Munch-Petersen B
FEBS J; 2009 Jan; 276(2):571-80. PubMed ID: 19087190
[TBL] [Abstract][Full Text] [Related]
13. Substrate specificity and molecular modelling of the feline herpesvirus-1 thymidine kinase.
Hussein IT; Miguel RN; Tiley LS; Field HJ
Arch Virol; 2008; 153(3):495-505. PubMed ID: 18196203
[TBL] [Abstract][Full Text] [Related]
14. Enzyme regulatory site-directed drugs: study of the interactions of 5'-amino-2', 5'-dideoxythymidine (5'-AdThd) and thymidine triphosphate with thymidine kinase and the relationship to the stimulation of thymidine uptake by 5'-AdThd in 647V cells.
Vazquez-Padua MA; Kunugi K; Fischer PH
Mol Pharmacol; 1989 Jan; 35(1):98-104. PubMed ID: 2536472
[TBL] [Abstract][Full Text] [Related]
15. Comparative active-site mutation study of human and Caenorhabditis elegans thymidine kinase 1.
Skovgaard T; Uhlin U; Munch-Petersen B
FEBS J; 2012 May; 279(10):1777-87. PubMed ID: 22385435
[TBL] [Abstract][Full Text] [Related]
16. Structures of human thymidylate kinase in complex with prodrugs: implications for the structure-based design of novel compounds.
Ostermann N; Segura-Peña D; Meier C; Veit T; Monnerjahn C; Konrad M; Lavie A
Biochemistry; 2003 Mar; 42(9):2568-77. PubMed ID: 12614151
[TBL] [Abstract][Full Text] [Related]
17. Enzymatic regulation of cytosolic thymidine kinase 1 and mitochondrial thymidine kinase 2: a mini review.
Munch-Petersen B
Nucleosides Nucleotides Nucleic Acids; 2010 Jun; 29(4-6):363-9. PubMed ID: 20544521
[TBL] [Abstract][Full Text] [Related]
18. Enzyme kinetics of thymidine kinase isoenzymes of Ehrlich ascites tumour.
He QM; Skog S; Welander I; Tribukait B
Anticancer Res; 1990; 10(5A):1257-63. PubMed ID: 2241101
[TBL] [Abstract][Full Text] [Related]
19. Methylene substitution at the alpha-beta bridging position within the phosphate chain of dUDP profoundly perturbs ligand accommodation into the dUTPase active site.
Kovári J; Barabás O; Varga B; Békési A; Tölgyesi F; Fidy J; Nagy J; Vértessy BG
Proteins; 2008 Apr; 71(1):308-19. PubMed ID: 17932923
[TBL] [Abstract][Full Text] [Related]
20. Biophysical characterization of vaccinia virus thymidine kinase substrate utilization.
Smith RF; Freyer MW; Lewis EA
J Virol Methods; 2007 Jun; 142(1-2):151-8. PubMed ID: 17335913
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]