285 related articles for article (PubMed ID: 16339184)
1. Dysregulation of the Hedgehog pathway in human hepatocarcinogenesis.
Sicklick JK; Li YX; Jayaraman A; Kannangai R; Qi Y; Vivekanandan P; Ludlow JW; Owzar K; Chen W; Torbenson MS; Diehl AM
Carcinogenesis; 2006 Apr; 27(4):748-57. PubMed ID: 16339184
[TBL] [Abstract][Full Text] [Related]
2. Small-molecule modulators of Hedgehog signaling: identification and characterization of Smoothened agonists and antagonists.
Frank-Kamenetsky M; Zhang XM; Bottega S; Guicherit O; Wichterle H; Dudek H; Bumcrot D; Wang FY; Jones S; Shulok J; Rubin LL; Porter JA
J Biol; 2002 Nov; 1(2):10. PubMed ID: 12437772
[TBL] [Abstract][Full Text] [Related]
3. Response to inhibition of smoothened in diverse epithelial cancer cells that lack smoothened or patched 1 mutations.
Galimberti F; Busch AM; Chinyengetere F; Ma T; Sekula D; Memoli VA; Dragnev KH; Liu F; Johnson KC; Guo Y; Freemantle SJ; Andrew AS; Greninger P; Robbins DJ; Settleman J; Benes C; Dmitrovsky E
Int J Oncol; 2012 Nov; 41(5):1751-61. PubMed ID: 22923130
[TBL] [Abstract][Full Text] [Related]
4. Activation of the hedgehog pathway in human hepatocellular carcinomas.
Huang S; He J; Zhang X; Bian Y; Yang L; Xie G; Zhang K; Tang W; Stelter AA; Wang Q; Zhang H; Xie J
Carcinogenesis; 2006 Jul; 27(7):1334-40. PubMed ID: 16501253
[TBL] [Abstract][Full Text] [Related]
5. Identification and characterization of Hedgehog modulator properties after functional coupling of Smoothened to G15.
Masdeu C; Faure H; Coulombe J; Schoenfelder A; Mann A; Brabet I; Pin JP; Traiffort E; Ruat M
Biochem Biophys Res Commun; 2006 Oct; 349(2):471-9. PubMed ID: 16945339
[TBL] [Abstract][Full Text] [Related]
6. Epigenetic high regulation of ATAD2 regulates the Hh pathway in human hepatocellular carcinoma.
Wu G; Lu X; Wang Y; He H; Meng X; Xia S; Zhen K; Liu Y
Int J Oncol; 2014 Jul; 45(1):351-61. PubMed ID: 24805933
[TBL] [Abstract][Full Text] [Related]
7. Selective down-regulation of glioma-associated oncogene 2 inhibits the proliferation of hepatocellular carcinoma cells.
Kim Y; Yoon JW; Xiao X; Dean NM; Monia BP; Marcusson EG
Cancer Res; 2007 Apr; 67(8):3583-93. PubMed ID: 17440069
[TBL] [Abstract][Full Text] [Related]
8. Patched acts catalytically to suppress the activity of Smoothened.
Taipale J; Cooper MK; Maiti T; Beachy PA
Nature; 2002 Aug; 418(6900):892-7. PubMed ID: 12192414
[TBL] [Abstract][Full Text] [Related]
9. Functional domains and sub-cellular distribution of the Hedgehog transducing protein Smoothened in Drosophila.
Nakano Y; Nystedt S; Shivdasani AA; Strutt H; Thomas C; Ingham PW
Mech Dev; 2004 Jun; 121(6):507-18. PubMed ID: 15172682
[TBL] [Abstract][Full Text] [Related]
10. Identification and mechanism of action of the acylguanidine MRT-83, a novel potent Smoothened antagonist.
Roudaut H; Traiffort E; Gorojankina T; Vincent L; Faure H; Schoenfelder A; Mann A; Manetti F; Solinas A; Taddei M; Ruat M
Mol Pharmacol; 2011 Mar; 79(3):453-60. PubMed ID: 21177415
[TBL] [Abstract][Full Text] [Related]
11. Hedgehog signaling overrides p53-mediated tumor suppression by activating Mdm2.
Abe Y; Oda-Sato E; Tobiume K; Kawauchi K; Taya Y; Okamoto K; Oren M; Tanaka N
Proc Natl Acad Sci U S A; 2008 Mar; 105(12):4838-43. PubMed ID: 18359851
[TBL] [Abstract][Full Text] [Related]
12. Small molecule inhibition of GDC-0449 refractory smoothened mutants and downstream mechanisms of drug resistance.
Dijkgraaf GJ; Alicke B; Weinmann L; Januario T; West K; Modrusan Z; Burdick D; Goldsmith R; Robarge K; Sutherlin D; Scales SJ; Gould SE; Yauch RL; de Sauvage FJ
Cancer Res; 2011 Jan; 71(2):435-44. PubMed ID: 21123452
[TBL] [Abstract][Full Text] [Related]
13. Prostaglandin E2 promotes the cell growth and invasive ability of hepatocellular carcinoma cells by upregulating c-Myc expression via EP4 receptor and the PKA signaling pathway.
Xia S; Ma J; Bai X; Zhang H; Cheng S; Zhang M; Zhang L; Du M; Wang Y; Li H; Rong R; Shi F; Yang Q; Leng J
Oncol Rep; 2014 Oct; 32(4):1521-30. PubMed ID: 25109834
[TBL] [Abstract][Full Text] [Related]
14. Role of Hedgehog signaling pathway in proliferation and invasiveness of hepatocellular carcinoma cells.
Cheng WT; Xu K; Tian DY; Zhang ZG; Liu LJ; Chen Y
Int J Oncol; 2009 Mar; 34(3):829-36. PubMed ID: 19212688
[TBL] [Abstract][Full Text] [Related]
15. Regulation of smoothened by Drosophila G-protein-coupled receptor kinases.
Cheng S; Maier D; Neubueser D; Hipfner DR
Dev Biol; 2010 Jan; 337(1):99-109. PubMed ID: 19850026
[TBL] [Abstract][Full Text] [Related]
16. In vivo evidence that Patched and Smoothened constitute distinct binding and transducing components of a Hedgehog receptor complex.
Chen Y; Struhl G
Development; 1998 Dec; 125(24):4943-8. PubMed ID: 9811578
[TBL] [Abstract][Full Text] [Related]
17. Pleiotropic effects of methionine adenosyltransferases deregulation as determinants of liver cancer progression and prognosis.
Frau M; Feo F; Pascale RM
J Hepatol; 2013 Oct; 59(4):830-41. PubMed ID: 23665184
[TBL] [Abstract][Full Text] [Related]
18. The hedgehog signaling pathway in the mouse ovary.
Russell MC; Cowan RG; Harman RM; Walker AL; Quirk SM
Biol Reprod; 2007 Aug; 77(2):226-36. PubMed ID: 17392501
[TBL] [Abstract][Full Text] [Related]
19. Inhibition mechanism of a newly cloned candidate tumor suppressor gene JST during hepatocarcinogenesis and its abnormal expression in human hepatocellular carcinoma from Qidong liver cancer risk area, China.
Dong-Dong L; Xi-Ran Z
Hepatogastroenterology; 2004; 51(56):515-25. PubMed ID: 15086194
[TBL] [Abstract][Full Text] [Related]
20. Inhibition of Hedgehog-dependent tumors and cancer stem cells by a newly identified naturally occurring chemotype.
Infante P; Alfonsi R; Ingallina C; Quaglio D; Ghirga F; D'Acquarica I; Bernardi F; Di Magno L; Canettieri G; Screpanti I; Gulino A; Botta B; Mori M; Di Marcotullio L
Cell Death Dis; 2016 Sep; 7(9):e2376. PubMed ID: 27899820
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
