138 related articles for article (PubMed ID: 16339389)
1. Inactivation of the pure antiestrogen fulvestrant and other synthetic estrogen molecules by UDP-glucuronosyltransferase 1A enzymes expressed in breast tissue.
Chouinard S; Tessier M; Vernouillet G; Gauthier S; Labrie F; Barbier O; Bélanger A
Mol Pharmacol; 2006 Mar; 69(3):908-20. PubMed ID: 16339389
[TBL] [Abstract][Full Text] [Related]
2. Glucuronidation of catechol estrogens by expressed human UDP-glucuronosyltransferases (UGTs) 1A1, 1A3, and 2B7.
Cheng Z; Rios GR; King CD; Coffman BL; Green MD; Mojarrabi B; Mackenzie PI; Tephly TR
Toxicol Sci; 1998 Sep; 45(1):52-7. PubMed ID: 9848110
[TBL] [Abstract][Full Text] [Related]
3. Metabolic inactivation of estrogens in breast tissue by UDP-glucuronosyltransferase enzymes: an overview.
Guillemette C; Bélanger A; Lépine J
Breast Cancer Res; 2004; 6(6):246-54. PubMed ID: 15535854
[TBL] [Abstract][Full Text] [Related]
4. Epirubicin glucuronidation is catalyzed by human UDP-glucuronosyltransferase 2B7.
Innocenti F; Iyer L; Ramírez J; Green MD; Ratain MJ
Drug Metab Dispos; 2001 May; 29(5):686-92. PubMed ID: 11302935
[TBL] [Abstract][Full Text] [Related]
5. Gene expression of 17beta-estradiol-metabolizing isozymes: comparison of normal human mammary gland to normal human liver and to cultured human breast adenocarcinoma cells.
Lehmann L; Wagner J
Adv Exp Med Biol; 2008; 617():617-24. PubMed ID: 18497089
[TBL] [Abstract][Full Text] [Related]
6. Specificity and regioselectivity of the conjugation of estradiol, estrone, and their catecholestrogen and methoxyestrogen metabolites by human uridine diphospho-glucuronosyltransferases expressed in endometrium.
Lépine J; Bernard O; Plante M; Têtu B; Pelletier G; Labrie F; Bélanger A; Guillemette C
J Clin Endocrinol Metab; 2004 Oct; 89(10):5222-32. PubMed ID: 15472229
[TBL] [Abstract][Full Text] [Related]
7. The human UDP-glucuronosyltransferase UGT1A3 is highly selective towards N2 in the tetrazole ring of losartan, candesartan, and zolarsartan.
Alonen A; Finel M; Kostiainen R
Biochem Pharmacol; 2008 Sep; 76(6):763-72. PubMed ID: 18674515
[TBL] [Abstract][Full Text] [Related]
8. The configuration of the 17-hydroxy group variably influences the glucuronidation of beta-estradiol and epiestradiol by human UDP-glucuronosyltransferases.
Itäaho K; Mackenzie PI; Ikushiro S; Miners JO; Finel M
Drug Metab Dispos; 2008 Nov; 36(11):2307-15. PubMed ID: 18719240
[TBL] [Abstract][Full Text] [Related]
9. Identification of UDP-glucuronosyltransferases responsible for the glucuronidation of darexaban, an oral factor Xa inhibitor, in human liver and intestine.
Shiraga T; Yajima K; Suzuki K; Suzuki K; Hashimoto T; Iwatsubo T; Miyashita A; Usui T
Drug Metab Dispos; 2012 Feb; 40(2):276-82. PubMed ID: 22031623
[TBL] [Abstract][Full Text] [Related]
10. Regioselective glucuronidation of denopamine: marked species differences and identification of human udp-glucuronosyltransferase isoform.
Kaji H; Kume T
Drug Metab Dispos; 2005 Mar; 33(3):403-12. PubMed ID: 15608137
[TBL] [Abstract][Full Text] [Related]
11. Isoliquiritigenin showed strong inhibitory effects towards multiple UDP-glucuronosyltransferase (UGT) isoform-catalyzed 4-methylumbelliferone (4-MU) glucuronidation.
Lu H; Fang ZZ; Cao YF; Hu CM; Hong M; Sun XY; Li H; Liu Y; Fu X; Sun H
Fitoterapia; 2013 Jan; 84():208-12. PubMed ID: 23237733
[TBL] [Abstract][Full Text] [Related]
12. Identification of human UDP-glucuronosyltransferase isoform(s) responsible for the C-glucuronidation of phenylbutazone.
Nishiyama T; Kobori T; Arai K; Ogura K; Ohnuma T; Ishii K; Hayashi K; Hiratsuka A
Arch Biochem Biophys; 2006 Oct; 454(1):72-9. PubMed ID: 16949544
[TBL] [Abstract][Full Text] [Related]
13. Glucuronidation of amines and other xenobiotics catalyzed by expressed human UDP-glucuronosyltransferase 1A3.
Green MD; King CD; Mojarrabi B; Mackenzie PI; Tephly TR
Drug Metab Dispos; 1998 Jun; 26(6):507-12. PubMed ID: 9616184
[TBL] [Abstract][Full Text] [Related]
14. The UDP-glucuronosyltransferase 2B7 isozyme is responsible for gemfibrozil glucuronidation in the human liver.
Mano Y; Usui T; Kamimura H
Drug Metab Dispos; 2007 Nov; 35(11):2040-4. PubMed ID: 17670842
[TBL] [Abstract][Full Text] [Related]
15. In vitro characterisation of human renal and hepatic frusemide glucuronidation and identification of the UDP-glucuronosyltransferase enzymes involved in this pathway.
Kerdpin O; Knights KM; Elliot DJ; Miners JO
Biochem Pharmacol; 2008 Jul; 76(2):249-57. PubMed ID: 18541222
[TBL] [Abstract][Full Text] [Related]
16. Gastrointestinally distributed UDP-glucuronosyltransferase 1A10, which metabolizes estrogens and nonsteroidal anti-inflammatory drugs, depends upon phosphorylation.
Basu NK; Kubota S; Meselhy MR; Ciotti M; Chowdhury B; Hartori M; Owens IS
J Biol Chem; 2004 Jul; 279(27):28320-9. PubMed ID: 15117964
[TBL] [Abstract][Full Text] [Related]
17. Characterization of hepatic and intestinal glucuronidation of magnolol: application of the relative activity factor approach to decipher the contributions of multiple UDP-glucuronosyltransferase isoforms.
Zhu L; Ge G; Zhang H; Liu H; He G; Liang S; Zhang Y; Fang Z; Dong P; Finel M; Yang L
Drug Metab Dispos; 2012 Mar; 40(3):529-38. PubMed ID: 22180045
[TBL] [Abstract][Full Text] [Related]
18. Glucuronidation of anabolic androgenic steroids by recombinant human UDP-glucuronosyltransferases.
Kuuranne T; Kurkela M; Thevis M; Schänzer W; Finel M; Kostiainen R
Drug Metab Dispos; 2003 Sep; 31(9):1117-24. PubMed ID: 12920167
[TBL] [Abstract][Full Text] [Related]
19. Intestinal glucuronidation metabolism may have a greater impact on oral bioavailability than hepatic glucuronidation metabolism in humans: a study with raloxifene, substrate for UGT1A1, 1A8, 1A9, and 1A10.
Mizuma T
Int J Pharm; 2009 Aug; 378(1-2):140-1. PubMed ID: 19486934
[TBL] [Abstract][Full Text] [Related]
20. Glucuronidation of curcuminoids by human microsomal and recombinant UDP-glucuronosyltransferases.
Hoehle SI; Pfeiffer E; Metzler M
Mol Nutr Food Res; 2007 Aug; 51(8):932-8. PubMed ID: 17628876
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]