BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

238 related articles for article (PubMed ID: 16339550)

  • 1. T cell activation-induced CrkII binding to the Zap70 protein tyrosine kinase is mediated by Lck-dependent phosphorylation of Zap70 tyrosine 315.
    Gelkop S; Gish GD; Babichev Y; Pawson T; Isakov N
    J Immunol; 2005 Dec; 175(12):8123-32. PubMed ID: 16339550
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Crk adaptor proteins regulate CD3ζ chain phosphorylation and TCR/CD3 down-modulation in activated T cells.
    Dong G; Kalifa R; Nath PR; Babichev Y; Gelkop S; Isakov N
    Cell Signal; 2017 Aug; 36():117-126. PubMed ID: 28465009
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Tyrosine 192 within the SH2 domain of the Src-protein tyrosine kinase p56
    Kästle M; Merten C; Hartig R; Kaehne T; Liaunardy-Jopeace A; Woessner NM; Schamel WW; James J; Minguet S; Simeoni L; Schraven B
    Cell Commun Signal; 2020 Nov; 18(1):183. PubMed ID: 33225946
    [TBL] [Abstract][Full Text] [Related]  

  • 4. T cell activation stimulates the association of enzymatically active tyrosine-phosphorylated ZAP-70 with the Crk adapter proteins.
    Gelkop S; Isakov N
    J Biol Chem; 1999 Jul; 274(31):21519-27. PubMed ID: 10419455
    [TBL] [Abstract][Full Text] [Related]  

  • 5. TCR crosslinking promotes Crk adaptor protein binding to tyrosine-phosphorylated CD3ζ chain.
    Dong G; Kalifa R; Nath PR; Gelkop S; Isakov N
    Biochem Biophys Res Commun; 2017 Jul; 488(3):541-546. PubMed ID: 28526413
    [TBL] [Abstract][Full Text] [Related]  

  • 6. T cell activation induces direct binding of the Crk adapter protein to the regulatory subunit of phosphatidylinositol 3-kinase (p85) via a complex mechanism involving the Cbl protein.
    Gelkop S; Babichev Y; Isakov N
    J Biol Chem; 2001 Sep; 276(39):36174-82. PubMed ID: 11418612
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Phosphorylation of a Tyrosine Residue on Zap70 by Lck and Its Subsequent Binding via an SH2 Domain May Be a Key Gatekeeper of T Cell Receptor Signaling In Vivo.
    Thill PA; Weiss A; Chakraborty AK
    Mol Cell Biol; 2016 Sep; 36(18):2396-402. PubMed ID: 27354065
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Regulation of T cell development by c-Cbl: essential role of Lck.
    Chiang YJ; Hodes RJ
    Int Immunol; 2015 May; 27(5):245-51. PubMed ID: 25477210
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Roles of Lck, Syk and ZAP-70 tyrosine kinases in TCR-mediated phosphorylation of the adapter protein Shc.
    Walk SF; March ME; Ravichandran KS
    Eur J Immunol; 1998 Aug; 28(8):2265-75. PubMed ID: 9710204
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Differential Src family kinase activity requirements for CD3 zeta phosphorylation/ZAP70 recruitment and CD3 epsilon phosphorylation.
    Lysechko TL; Ostergaard HL
    J Immunol; 2005 Jun; 174(12):7807-14. PubMed ID: 15944285
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A weak Lck tail bite is necessary for Lck function in T cell antigen receptor signaling.
    Nika K; Tautz L; Arimura Y; Vang T; Williams S; Mustelin T
    J Biol Chem; 2007 Dec; 282(49):36000-9. PubMed ID: 17897955
    [TBL] [Abstract][Full Text] [Related]  

  • 12. MHC class I ligation of human T cells activates the ZAP70 and p56lck tyrosine kinases, leads to an alternative phenotype of the TCR/CD3 zeta-chain, and induces apoptosis.
    Skov S; Bregenholt S; Claesson MH
    J Immunol; 1997 Apr; 158(7):3189-96. PubMed ID: 9120273
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Involvement of hematopoietic progenitor kinase 1 in T cell receptor signaling.
    Ling P; Meyer CF; Redmond LP; Shui JW; Davis B; Rich RR; Hu MC; Wange RL; Tan TH
    J Biol Chem; 2001 Jun; 276(22):18908-14. PubMed ID: 11279207
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Lck promotes Zap70-dependent LAT phosphorylation by bridging Zap70 to LAT.
    Lo WL; Shah NH; Ahsan N; Horkova V; Stepanek O; Salomon AR; Kuriyan J; Weiss A
    Nat Immunol; 2018 Jul; 19(7):733-741. PubMed ID: 29915297
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Phospho-mimetic CD3ε variants prevent TCR and CAR signaling.
    Woessner NM; Brandl SM; Hartmann S; Schamel WW; Hartl FA; Minguet S
    Front Immunol; 2024; 15():1392933. PubMed ID: 38779683
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mapping the Zap-70 phosphorylation sites on LAT (linker for activation of T cells) required for recruitment and activation of signalling proteins in T cells.
    Paz PE; Wang S; Clarke H; Lu X; Stokoe D; Abo A
    Biochem J; 2001 Jun; 356(Pt 2):461-71. PubMed ID: 11368773
    [TBL] [Abstract][Full Text] [Related]  

  • 17. T cell regulation of p62(dok) (Dok1) association with Crk-L.
    Martelli MP; Boomer J; Bu M; Bierer BE
    J Biol Chem; 2001 Dec; 276(49):45654-61. PubMed ID: 11553620
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Lck-dependent tyrosine phosphorylation of diacylglycerol kinase alpha regulates its membrane association in T cells.
    Merino E; Avila-Flores A; Shirai Y; Moraga I; Saito N; Mérida I
    J Immunol; 2008 May; 180(9):5805-15. PubMed ID: 18424699
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Identification of substrates of human protein-tyrosine phosphatase PTPN22.
    Wu J; Katrekar A; Honigberg LA; Smith AM; Conn MT; Tang J; Jeffery D; Mortara K; Sampang J; Williams SR; Buggy J; Clark JM
    J Biol Chem; 2006 Apr; 281(16):11002-10. PubMed ID: 16461343
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Activation of Zap-70 tyrosine kinase due to a structural rearrangement induced by tyrosine phosphorylation and/or ITAM binding.
    Visco C; Magistrelli G; Bosotti R; Perego R; Rusconi L; Toma S; Zamai M; Acuto O; Isacchi A
    Biochemistry; 2000 Mar; 39(10):2784-91. PubMed ID: 10704231
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.