These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

123 related articles for article (PubMed ID: 1634512)

  • 1. Relation between the insulin receptor number in cells, autophosphorylation and insulin-stimulated Ras.GTP formation.
    Osterop AP; Medema RH; Bos JL; vd Zon GC; Moller DE; Flier JS; Möller W; Maassen JA
    J Biol Chem; 1992 Jul; 267(21):14647-53. PubMed ID: 1634512
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A mutant insulin receptor induces formation of a Shc-growth factor receptor bound protein 2 (Grb2) complex and p21ras-GTP without detectable interaction of insulin receptor substrate 1 (IRS1) with Grb2. Evidence for IRS1-independent p21ras-GTP formation.
    Ouwens DM; van der Zon GC; Pronk GJ; Bos JL; Möller W; Cheatham B; Kahn CR; Maassen JA
    J Biol Chem; 1994 Dec; 269(52):33116-22. PubMed ID: 7806540
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Activation of overexpressed receptors for insulin and epidermal growth factor interferes in mitogenic signaling without affecting the activation of p21ras.
    Osterop AP; Medema RH; Ouwens DM; Van der Zon GC; Möller W; Maassen JA
    Biochemistry; 1994 Jun; 33(23):7453-9. PubMed ID: 8003510
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Epidermal-growth-factor receptors generate Ras.GTP more efficiently than insulin receptors.
    Osterop AP; Medema RH; vd Zon GC; Bos JL; Möller W; Maassen JA
    Eur J Biochem; 1993 Mar; 212(2):477-82. PubMed ID: 8444185
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Insulin activates p21Ras and guanine nucleotide releasing factor in cells expressing wild type and mutant insulin receptors.
    Draznin B; Chang L; Leitner JW; Takata Y; Olefsky JM
    J Biol Chem; 1993 Sep; 268(27):19998-20001. PubMed ID: 8376360
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Enhanced insulin-induced mitogenesis and mitogen-activated protein kinase activities in mutant insulin receptors with substitution of two COOH-terminal tyrosine autophosphorylation sites by phenylalanine.
    Ando A; Momomura K; Tobe K; Yamamoto-Honda R; Sakura H; Tamori Y; Kaburagi Y; Koshio O; Akanuma Y; Yazaki Y
    J Biol Chem; 1992 Jun; 267(18):12788-96. PubMed ID: 1618780
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Differential role of insulin receptor autophosphorylation sites 1162 and 1163 in the long-term insulin stimulation of glucose transport, glycogenesis, and protein synthesis.
    Desbois C; Capeau J; Hainault I; Wicek D; Reynet C; Veissière D; Caron M; Picard J; Guerre-Millo M; Cherqui G
    J Biol Chem; 1992 Jul; 267(19):13488-97. PubMed ID: 1618850
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Shc is the predominant signaling molecule coupling insulin receptors to activation of guanine nucleotide releasing factor and p21ras-GTP formation.
    Sasaoka T; Draznin B; Leitner JW; Langlois WJ; Olefsky JM
    J Biol Chem; 1994 Apr; 269(14):10734-8. PubMed ID: 8144662
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Biologic activities of naturally occurring human insulin receptor mutations. Evidence that metabolic effects of insulin can be mediated by a kinase-deficient insulin receptor mutant.
    Moller DE; Benecke H; Flier JS
    J Biol Chem; 1991 Jun; 266(17):10995-1001. PubMed ID: 1645719
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Signal transduction pathways from insulin receptors to Ras. Analysis by mutant insulin receptors.
    Yonezawa K; Ando A; Kaburagi Y; Yamamoto-Honda R; Kitamura T; Hara K; Nakafuku M; Okabayashi Y; Kadowaki T; Kaziro Y
    J Biol Chem; 1994 Feb; 269(6):4634-40. PubMed ID: 7508445
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Increased levels of p21ras-GTP and enhanced DNA synthesis accompany elevated tyrosyl phosphorylation of GAP-associated proteins, p190 and p62, in c-src overexpressors.
    Chang JH; Wilson LK; Moyers JS; Zhang K; Parsons SJ
    Oncogene; 1993 Apr; 8(4):959-67. PubMed ID: 7681161
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Ras-independent and wortmannin-sensitive activation of glycogen synthase by insulin in Chinese hamster ovary cells.
    Sakaue H; Hara K; Noguchi T; Matozaki T; Kotani K; Ogawa W; Yonezawa K; Waterfield MD; Kasuga M
    J Biol Chem; 1995 May; 270(19):11304-9. PubMed ID: 7744767
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Platelet-derived growth factor stimulation of GTPase-activating protein tyrosine phosphorylation in control and c-H-ras-expressing NIH 3T3 cells correlates with p21ras activation.
    Molloy CJ; Fleming TP; Bottaro DP; Cuadrado A; Aaronson SA
    Mol Cell Biol; 1992 Sep; 12(9):3903-9. PubMed ID: 1508192
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Platelet-derived growth factor stimulates formation of active p21ras.GTP complex in Swiss mouse 3T3 cells.
    Satoh T; Endo M; Nakafuku M; Nakamura S; Kaziro Y
    Proc Natl Acad Sci U S A; 1990 Aug; 87(15):5993-7. PubMed ID: 2198577
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Recombinant human alpha 2-HS glycoprotein inhibits insulin-stimulated mitogenic pathway without affecting metabolic signalling in Chinese hamster ovary cells overexpressing the human insulin receptor.
    Srinivas PR; Deutsch DD; Mathews ST; Goustin AS; Leon MA; Grunberger G
    Cell Signal; 1996 Dec; 8(8):567-73. PubMed ID: 9115849
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Activation of Ras by insulin in 3T3 L1 cells does not involve GTPase-activating protein phosphorylation.
    Porras A; Nebreda AR; Benito M; Santos E
    J Biol Chem; 1992 Oct; 267(29):21124-31. PubMed ID: 1328223
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Insulin stimulation of phosphatidylinositol 3-kinase activity maps to insulin receptor regions required for endogenous substrate phosphorylation.
    Backer JM; Schroeder GG; Kahn CR; Myers MG; Wilden PA; Cahill DA; White MF
    J Biol Chem; 1992 Jan; 267(2):1367-74. PubMed ID: 1309768
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Two naturally occurring insulin receptor tyrosine kinase domain mutants provide evidence that phosphoinositide 3-kinase activation alone is not sufficient for the mediation of insulin's metabolic and mitogenic effects.
    Krook A; Whitehead JP; Dobson SP; Griffiths MR; Ouwens M; Baker C; Hayward AC; Sen SK; Maassen JA; Siddle K; Tavaré JM; O'Rahilly S
    J Biol Chem; 1997 Nov; 272(48):30208-14. PubMed ID: 9374504
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Functional activation of mutant human insulin receptor by monoclonal antibody.
    Krook A; Soos MA; Kumar S; Siddle K; O'Rahilly S
    Lancet; 1996 Jun; 347(9015):1586-90. PubMed ID: 8667867
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A dominant-negative mutant of mSOS1 inhibits insulin-induced Ras activation and reveals Ras-dependent and -independent insulin signaling pathways.
    Sakaue M; Bowtell D; Kasuga M
    Mol Cell Biol; 1995 Jan; 15(1):379-88. PubMed ID: 7799946
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.