These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

123 related articles for article (PubMed ID: 16350945)

  • 1. Computer-aided design of small molecules for chemical genomics.
    Dean PM
    Methods Mol Biol; 2005; 310():25-39. PubMed ID: 16350945
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Chemical genomics: a challenge for de novo drug design.
    Dean PM
    Mol Biotechnol; 2007 Nov; 37(3):237-45. PubMed ID: 17952670
    [TBL] [Abstract][Full Text] [Related]  

  • 3. LEA3D: a computer-aided ligand design for structure-based drug design.
    Douguet D; Munier-Lehmann H; Labesse G; Pochet S
    J Med Chem; 2005 Apr; 48(7):2457-68. PubMed ID: 15801836
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Computer-based design of novel protein structures.
    Butterfoss GL; Kuhlman B
    Annu Rev Biophys Biomol Struct; 2006; 35():49-65. PubMed ID: 16689627
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Recent advances in de novo design strategy for practical lead identification.
    Honma T
    Med Res Rev; 2003 Sep; 23(5):606-32. PubMed ID: 12789688
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Enhancing reaction-based de novo design using a multi-label reaction class recommender.
    Ghiandoni GM; Bodkin MJ; Chen B; Hristozov D; Wallace JEA; Webster J; Gillet VJ
    J Comput Aided Mol Des; 2020 Jul; 34(7):783-803. PubMed ID: 32112286
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Meeting on binding sites: characterizing and satisfying steric and chemical restraints. University of York, 28-30 March 1993.
    Slater T; Timms D
    J Mol Graph; 1993 Dec; 11(4):248-51. PubMed ID: 8136328
    [No Abstract]   [Full Text] [Related]  

  • 8. Chemogenomic approaches to rational drug design.
    Rognan D
    Br J Pharmacol; 2007 Sep; 152(1):38-52. PubMed ID: 17533416
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Evolutionary algorithms in computer-aided molecular design.
    Clark DE; Westhead DR
    J Comput Aided Mol Des; 1996 Aug; 10(4):337-58. PubMed ID: 8877705
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Computer-Aided Drug Design: An Overview.
    Talevi A
    Methods Mol Biol; 2018; 1762():1-19. PubMed ID: 29594764
    [TBL] [Abstract][Full Text] [Related]  

  • 11. [Development of antituberculous drugs: current status and future prospects].
    Tomioka H; Namba K
    Kekkaku; 2006 Dec; 81(12):753-74. PubMed ID: 17240921
    [TBL] [Abstract][Full Text] [Related]  

  • 12. From drug target to leads--sketching a physicochemical pathway for lead molecule design in silico.
    Shaikh SA; Jain T; Sandhu G; Latha N; Jayaram B
    Curr Pharm Des; 2007; 13(34):3454-70. PubMed ID: 18220783
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The effect of a tightly bound water molecule on scaffold diversity in the computer-aided de novo ligand design of CDK2 inhibitors.
    García-Sosa AT; Mancera RL
    J Mol Model; 2006 Mar; 12(4):422-31. PubMed ID: 16374623
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Modern computational chemistry and drug discovery: structure generating programs.
    Bohacek RS; McMartin C
    Curr Opin Chem Biol; 1997 Aug; 1(2):157-61. PubMed ID: 9667851
    [TBL] [Abstract][Full Text] [Related]  

  • 15. In silico multi-filter screening approaches for developing novel beta-secretase inhibitors.
    Fujimoto T; Matsushita Y; Gouda H; Yamaotsu N; Hirono S
    Bioorg Med Chem Lett; 2008 May; 18(9):2771-5. PubMed ID: 18434150
    [TBL] [Abstract][Full Text] [Related]  

  • 16. De novo drug design.
    Hartenfeller M; Schneider G
    Methods Mol Biol; 2011; 672():299-323. PubMed ID: 20838974
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Reinforced Adversarial Neural Computer for de Novo Molecular Design.
    Putin E; Asadulaev A; Ivanenkov Y; Aladinskiy V; Sanchez-Lengeling B; Aspuru-Guzik A; Zhavoronkov A
    J Chem Inf Model; 2018 Jun; 58(6):1194-1204. PubMed ID: 29762023
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Reaction-driven de novo design, synthesis and testing of potential type II kinase inhibitors.
    Schneider G; Geppert T; Hartenfeller M; Reisen F; Klenner A; Reutlinger M; Hähnke V; Hiss JA; Zettl H; Keppner S; Spänkuch B; Schneider P
    Future Med Chem; 2011 Mar; 3(4):415-24. PubMed ID: 21452978
    [TBL] [Abstract][Full Text] [Related]  

  • 19. PRO-LIGAND: an approach to de novo molecular design. 3. A genetic algorithm for structure refinement.
    Westhead DR; Clark DE; Frenkel D; Li J; Murray CW; Robson B; Waszkowycz B
    J Comput Aided Mol Des; 1995 Apr; 9(2):139-48. PubMed ID: 7608745
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Ring system-based chemical graph generation for de novo molecular design.
    Miyao T; Kaneko H; Funatsu K
    J Comput Aided Mol Des; 2016 May; 30(5):425-46. PubMed ID: 27299746
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.