213 related articles for article (PubMed ID: 16351096)
1. Hybrids of the hemiasterlin analogue taltobulin and the dolastatins are potent antimicrotubule agents.
Zask A; Kaplan J; Musto S; Loganzo F
J Am Chem Soc; 2005 Dec; 127(50):17667-71. PubMed ID: 16351096
[TBL] [Abstract][Full Text] [Related]
2. HTI-286, a synthetic analogue of the tripeptide hemiasterlin, is a potent antimicrotubule agent that circumvents P-glycoprotein-mediated resistance in vitro and in vivo.
Loganzo F; Discafani CM; Annable T; Beyer C; Musto S; Hari M; Tan X; Hardy C; Hernandez R; Baxter M; Singanallore T; Khafizova G; Poruchynsky MS; Fojo T; Nieman JA; Ayral-Kaloustian S; Zask A; Andersen RJ; Greenberger LM
Cancer Res; 2003 Apr; 63(8):1838-45. PubMed ID: 12702571
[TBL] [Abstract][Full Text] [Related]
3. Two photoaffinity analogues of the tripeptide, hemiasterlin, exclusively label alpha-tubulin.
Nunes M; Kaplan J; Wooters J; Hari M; Minnick AA; May MK; Shi C; Musto S; Beyer C; Krishnamurthy G; Qiu Y; Loganzo F; Ayral-Kaloustian S; Zask A; Greenberger LM
Biochemistry; 2005 May; 44(18):6844-57. PubMed ID: 15865430
[TBL] [Abstract][Full Text] [Related]
4. 9-Benzylidene-naphtho[2,3-b]thiophen-4-ones as novel antimicrotubule agents-synthesis, antiproliferative activity, and inhibition of tubulin polymerization.
Zuse A; Schmidt P; Baasner S; Böhm KJ; Müller K; Gerlach M; Günther EG; Unger E; Prinz H
J Med Chem; 2006 Dec; 49(26):7816-25. PubMed ID: 17181164
[TBL] [Abstract][Full Text] [Related]
5. Synthesis and biological activity of analogues of the antimicrotubule agent N,beta,beta-trimethyl-L-phenylalanyl-N(1)-[(1S,2E)-3-carboxy-1-isopropylbut-2-enyl]- N(1),3-dimethyl-L-valinamide (HTI-286).
Zask A; Birnberg G; Cheung K; Kaplan J; Niu C; Norton E; Suayan R; Yamashita A; Cole D; Tang Z; Krishnamurthy G; Williamson R; Khafizova G; Musto S; Hernandez R; Annable T; Yang X; Discafani C; Beyer C; Greenberger LM; Loganzo F; Ayral-Kaloustian S
J Med Chem; 2004 Sep; 47(19):4774-86. PubMed ID: 15341492
[TBL] [Abstract][Full Text] [Related]
6. Synthesis and activity of novel analogs of hemiasterlin as inhibitors of tubulin polymerization: modification of the A segment.
Yamashita A; Norton EB; Kaplan JA; Niu C; Loganzo F; Hernandez R; Beyer CF; Annable T; Musto S; Discafani C; Zask A; Ayral-Kaloustian S
Bioorg Med Chem Lett; 2004 Nov; 14(21):5317-22. PubMed ID: 15454219
[TBL] [Abstract][Full Text] [Related]
7. Antineoplastic agents 365. Dolastatin 10 SAR probes.
Pettit GR; Srirangam JK; Barkoczy J; Williams MD; Boyd MR; Hamel E; Pettit RK; Hogan F; Bai R; Chapuis JC; McAllister SC; Schmidt JM
Anticancer Drug Des; 1998 Jun; 13(4):243-77. PubMed ID: 9627667
[TBL] [Abstract][Full Text] [Related]
8. Synthesis and biological activity of chimeric structures derived from the cytotoxic natural compounds dolastatin 10 and dolastatin 15.
Poncet J; Busquet M; Roux F; Pierré A; Atassi G; Jouin P
J Med Chem; 1998 Apr; 41(9):1524-30. PubMed ID: 9554885
[TBL] [Abstract][Full Text] [Related]
9. Synthesis and antimitotic/cytotoxic activity of hemiasterlin analogues.
Nieman JA; Coleman JE; Wallace DJ; Piers E; Lim LY; Roberge M; Andersen RJ
J Nat Prod; 2003 Feb; 66(2):183-99. PubMed ID: 12608848
[TBL] [Abstract][Full Text] [Related]
10. Synthesis and biological evaluation of 2-amino-3-(3',4',5'-trimethoxybenzoyl)-5-aryl thiophenes as a new class of potent antitubulin agents.
Romagnoli R; Baraldi PG; Pavani MG; Tabrizi MA; Preti D; Fruttarolo F; Piccagli L; Jung MK; Hamel E; Borgatti M; Gambari R
J Med Chem; 2006 Jun; 49(13):3906-15. PubMed ID: 16789746
[TBL] [Abstract][Full Text] [Related]
11. Benzoylphenylurea sulfur analogues with potent antitumor activity.
Hallur G; Jimeno A; Dalrymple S; Zhu T; Jung MK; Hidalgo M; Isaacs JT; Sukumar S; Hamel E; Khan SR
J Med Chem; 2006 Apr; 49(7):2357-60. PubMed ID: 16570932
[TBL] [Abstract][Full Text] [Related]
12. 10-(2-oxo-2-phenylethylidene)-10H-anthracen-9-ones as highly active antimicrotubule agents: synthesis, antiproliferative activity, and inhibition of tubulin polymerization.
Prinz H; Schmidt P; Böhm KJ; Baasner S; Müller K; Unger E; Gerlach M; Günther EG
J Med Chem; 2009 Mar; 52(5):1284-94. PubMed ID: 19220018
[TBL] [Abstract][Full Text] [Related]
13. Synthesis and structure-activity relationships of 1,2,4-triazoles as a novel class of potent tubulin polymerization inhibitors.
Ouyang X; Chen X; Piatnitski EL; Kiselyov AS; He HY; Mao Y; Pattaropong V; Yu Y; Kim KH; Kincaid J; Smith L; Wong WC; Lee SP; Milligan DL; Malikzay A; Fleming J; Gerlak J; Deevi D; Doody JF; Chiang HH; Patel SN; Wang Y; Rolser RL; Kussie P; Labelle M; Tuma MC
Bioorg Med Chem Lett; 2005 Dec; 15(23):5154-9. PubMed ID: 16198562
[TBL] [Abstract][Full Text] [Related]
14. 4- and 5-aroylindoles as novel classes of potent antitubulin agents.
Liou JP; Wu CY; Hsieh HP; Chang CY; Chen CM; Kuo CC; Chang JY
J Med Chem; 2007 Sep; 50(18):4548-52. PubMed ID: 17685504
[TBL] [Abstract][Full Text] [Related]
15. Tumor cells resistant to a microtubule-depolymerizing hemiasterlin analogue, HTI-286, have mutations in alpha- or beta-tubulin and increased microtubule stability.
Poruchynsky MS; Kim JH; Nogales E; Annable T; Loganzo F; Greenberger LM; Sackett DL; Fojo T
Biochemistry; 2004 Nov; 43(44):13944-54. PubMed ID: 15518543
[TBL] [Abstract][Full Text] [Related]
16. Structure-based identification of the binding site for the hemiasterlin analogue HTI-286 on tubulin.
Ravi M; Zask A; Rush TS
Biochemistry; 2005 Dec; 44(48):15871-9. PubMed ID: 16313189
[TBL] [Abstract][Full Text] [Related]
17. Sulfonate derivatives of naphtho[2,3-b]thiophen-4(9H)-one and 9(10H)-anthracenone as highly active antimicrotubule agents. Synthesis, antiproliferative activity, and inhibition of tubulin polymerization.
Zuse A; Schmidt P; Baasner S; Böhm KJ; Müller K; Gerlach M; Günther EG; Unger E; Prinz H
J Med Chem; 2007 Nov; 50(24):6059-66. PubMed ID: 17973361
[TBL] [Abstract][Full Text] [Related]
18. 2-amino and 2'-aminocombretastatin derivatives as potent antimitotic agents.
Chang JY; Yang MF; Chang CY; Chen CM; Kuo CC; Liou JP
J Med Chem; 2006 Oct; 49(21):6412-5. PubMed ID: 17034147
[TBL] [Abstract][Full Text] [Related]
19. Novel tubulin-polymerization inhibitor derived from thalidomide directly induces apoptosis in human multiple myeloma cells: possible anti-myeloma mechanism of thalidomide.
Iguchi T; Yachide-Noguchi T; Hashimoto Y; Nakazato S; Sagawa M; Ikeda Y; Kizaki M
Int J Mol Med; 2008 Feb; 21(2):163-8. PubMed ID: 18204782
[TBL] [Abstract][Full Text] [Related]
20. Tubulin photoaffinity labeling with biotin-tagged derivatives of potent diketopiperazine antimicrotubule agents.
Yamazaki Y; Kohno K; Yasui H; Kiso Y; Akamatsu M; Nicholson B; Deyanat-Yazdi G; Neuteboom S; Potts B; Lloyd GK; Hayashi Y
Chembiochem; 2008 Dec; 9(18):3074-81. PubMed ID: 19012291
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]