BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

208 related articles for article (PubMed ID: 16352531)

  • 1. Anti-CD45RO suppresses human immunodeficiency virus type 1 replication in microglia: role of Hck tyrosine kinase and implications for AIDS dementia.
    Kim MO; Suh HS; Si Q; Terman BI; Lee SC
    J Virol; 2006 Jan; 80(1):62-72. PubMed ID: 16352531
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inhibition of granulocyte-macrophage colony-stimulating factor signaling and microglial proliferation by anti-CD45RO: role of Hck tyrosine kinase and phosphatidylinositol 3-kinase/Akt.
    Suh HS; Kim MO; Lee SC
    J Immunol; 2005 Mar; 174(5):2712-9. PubMed ID: 15728479
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The human immunodeficiency virus type 1 Nef protein binds the Src-related tyrosine kinase Lck SH2 domain through a novel phosphotyrosine independent mechanism.
    Dutartre H; Harris M; Olive D; Collette Y
    Virology; 1998 Aug; 247(2):200-11. PubMed ID: 9705913
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Conserved residues in the HIV-1 Nef hydrophobic pocket are essential for recruitment and activation of the Hck tyrosine kinase.
    Choi HJ; Smithgall TE
    J Mol Biol; 2004 Nov; 343(5):1255-68. PubMed ID: 15491611
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Oligomerization is required for HIV-1 Nef-induced activation of the Src family protein-tyrosine kinase, Hck.
    Ye H; Choi HJ; Poe J; Smithgall TE
    Biochemistry; 2004 Dec; 43(50):15775-84. PubMed ID: 15595833
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Activation of the Src-family tyrosine kinase Hck by SH3 domain displacement.
    Moarefi I; LaFevre-Bernt M; Sicheri F; Huse M; Lee CH; Kuriyan J; Miller WT
    Nature; 1997 Feb; 385(6617):650-3. PubMed ID: 9024665
    [TBL] [Abstract][Full Text] [Related]  

  • 7. SH3-mediated Hck tyrosine kinase activation and fibroblast transformation by the Nef protein of HIV-1.
    Briggs SD; Sharkey M; Stevenson M; Smithgall TE
    J Biol Chem; 1997 Jul; 272(29):17899-902. PubMed ID: 9218412
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Subtle Dynamic Changes Accompany Hck Activation by HIV-1 Nef and are Reversed by an Antiretroviral Kinase Inhibitor.
    Wales TE; Hochrein JM; Morgan CR; Emert-Sedlak LA; Smithgall TE; Engen JR
    Biochemistry; 2015 Oct; 54(41):6382-91. PubMed ID: 26440750
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The tyrosine kinase Hck is an inhibitor of HIV-1 replication counteracted by the viral vif protein.
    Hassaïne G; Courcoul M; Bessou G; Barthalay Y; Picard C; Olive D; Collette Y; Vigne R; Decroly E
    J Biol Chem; 2001 May; 276(20):16885-93. PubMed ID: 11278465
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Affinity of Src family kinase SH3 domains for HIV Nef in vitro does not predict kinase activation by Nef in vivo.
    Briggs SD; Lerner EC; Smithgall TE
    Biochemistry; 2000 Jan; 39(3):489-95. PubMed ID: 10642173
    [TBL] [Abstract][Full Text] [Related]  

  • 11. HIV-1 infection of T cells and macrophages are differentially modulated by virion-associated Hck: a Nef-dependent phenomenon.
    Cornall A; Mak J; Greenway A; Tachedjian G
    Viruses; 2013 Sep; 5(9):2235-52. PubMed ID: 24051604
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Induction of activator protein 1 (AP-1) in macrophages by human immunodeficiency virus type-1 NEF is a cell-type-specific response that requires both hck and MAPK signaling events.
    Biggs TE; Cooke SJ; Barton CH; Harris MP; Saksela K; Mann DA
    J Mol Biol; 1999 Jul; 290(1):21-35. PubMed ID: 10388555
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Interaction with the Src homology (SH3-SH2) region of the Src-family kinase Hck structures the HIV-1 Nef dimer for kinase activation and effector recruitment.
    Alvarado JJ; Tarafdar S; Yeh JI; Smithgall TE
    J Biol Chem; 2014 Oct; 289(41):28539-53. PubMed ID: 25122770
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A single amino acid in the SH3 domain of Hck determines its high affinity and specificity in binding to HIV-1 Nef protein.
    Lee CH; Leung B; Lemmon MA; Zheng J; Cowburn D; Kuriyan J; Saksela K
    EMBO J; 1995 Oct; 14(20):5006-15. PubMed ID: 7588629
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Simian immunodeficiency virus and human immunodeficiency virus type 1 nef proteins show distinct patterns and mechanisms of Src kinase activation.
    Greenway AL; Dutartre H; Allen K; McPhee DA; Olive D; Collette Y
    J Virol; 1999 Jul; 73(7):6152-8. PubMed ID: 10364375
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A mammalian two-hybrid screening system for inhibitors of interaction between HIV Nef and the cellular tyrosine kinase Hck.
    Murakami Y; Fukazawa H; Kobatake T; Yamagoe S; Takebe Y; Tobiume M; Matsuda M; Uehara Y
    Antiviral Res; 2002 Jul; 55(1):161-8. PubMed ID: 12076760
    [TBL] [Abstract][Full Text] [Related]  

  • 17. HIV-1 Nef selectively activates Src family kinases Hck, Lyn, and c-Src through direct SH3 domain interaction.
    Trible RP; Emert-Sedlak L; Smithgall TE
    J Biol Chem; 2006 Sep; 281(37):27029-38. PubMed ID: 16849330
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The pathogenicity of human immunodeficiency virus (HIV) type 1 Nef in CD4C/HIV transgenic mice is abolished by mutation of its SH3-binding domain, and disease development is delayed in the absence of Hck.
    Hanna Z; Weng X; Kay DG; Poudrier J; Lowell C; Jolicoeur P
    J Virol; 2001 Oct; 75(19):9378-92. PubMed ID: 11533201
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Hck SH3 domain-dependent abrogation of Nef-induced class 1 MHC down-regulation.
    Chang AH; O'Shaughnessy MV; Jirik FR
    Eur J Immunol; 2001 Aug; 31(8):2382-7. PubMed ID: 11500821
    [TBL] [Abstract][Full Text] [Related]  

  • 20. SH3-dependent stimulation of Src-family kinase autophosphorylation without tail release from the SH2 domain in vivo.
    Lerner EC; Smithgall TE
    Nat Struct Biol; 2002 May; 9(5):365-9. PubMed ID: 11976726
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.