BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

398 related articles for article (PubMed ID: 16352719)

  • 1. Leucine-rich repeat kinase 2 (LRRK2) interacts with parkin, and mutant LRRK2 induces neuronal degeneration.
    Smith WW; Pei Z; Jiang H; Moore DJ; Liang Y; West AB; Dawson VL; Dawson TM; Ross CA
    Proc Natl Acad Sci U S A; 2005 Dec; 102(51):18676-81. PubMed ID: 16352719
    [TBL] [Abstract][Full Text] [Related]  

  • 2. LRRK2 and parkin immunoreactivity in multiple system atrophy inclusions.
    Huang Y; Song YJ; Murphy K; Holton JL; Lashley T; Revesz T; Gai WP; Halliday GM
    Acta Neuropathol; 2008 Dec; 116(6):639-46. PubMed ID: 18936941
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Leucine-rich repeat kinase 2 regulates the progression of neuropathology induced by Parkinson's-disease-related mutant alpha-synuclein.
    Lin X; Parisiadou L; Gu XL; Wang L; Shim H; Sun L; Xie C; Long CX; Yang WJ; Ding J; Chen ZZ; Gallant PE; Tao-Cheng JH; Rudow G; Troncoso JC; Liu Z; Li Z; Cai H
    Neuron; 2009 Dec; 64(6):807-27. PubMed ID: 20064389
    [TBL] [Abstract][Full Text] [Related]  

  • 4. LRRK2 and neurodegeneration.
    Santpere G; Ferrer I
    Acta Neuropathol; 2009 Mar; 117(3):227-46. PubMed ID: 19142648
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Role of autophagy in G2019S-LRRK2-associated neurite shortening in differentiated SH-SY5Y cells.
    Plowey ED; Cherra SJ; Liu YJ; Chu CT
    J Neurochem; 2008 May; 105(3):1048-56. PubMed ID: 18182054
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Leucine-Rich Repeat Kinase 2 interacts with Parkin, DJ-1 and PINK-1 in a Drosophila melanogaster model of Parkinson's disease.
    Venderova K; Kabbach G; Abdel-Messih E; Zhang Y; Parks RJ; Imai Y; Gehrke S; Ngsee J; Lavoie MJ; Slack RS; Rao Y; Zhang Z; Lu B; Haque ME; Park DS
    Hum Mol Genet; 2009 Nov; 18(22):4390-404. PubMed ID: 19692353
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Analysis of LRRK2, SNCA, Parkin, PINK1, and DJ-1 in Zambian patients with Parkinson's disease.
    Yonova-Doing E; Atadzhanov M; Quadri M; Kelly P; Shawa N; Musonda ST; Simons EJ; Breedveld GJ; Oostra BA; Bonifati V
    Parkinsonism Relat Disord; 2012 Jun; 18(5):567-71. PubMed ID: 22445250
    [TBL] [Abstract][Full Text] [Related]  

  • 8. [Clinical molecular genetics for PARK8 (LRRK2)].
    Tomiyama H; Hatano T; Hattori N
    Brain Nerve; 2007 Aug; 59(8):839-50. PubMed ID: 17713120
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Leucine-rich repeat kinase 2 induces alpha-synuclein expression via the extracellular signal-regulated kinase pathway.
    Carballo-Carbajal I; Weber-Endress S; Rovelli G; Chan D; Wolozin B; Klein CL; Patenge N; Gasser T; Kahle PJ
    Cell Signal; 2010 May; 22(5):821-7. PubMed ID: 20074637
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synphilin-1 attenuates mutant LRRK2-induced neurodegeneration in Parkinson's disease models.
    Liu J; Li T; Thomas JM; Pei Z; Jiang H; Engelender S; Ross CA; Smith WW
    Hum Mol Genet; 2016 Feb; 25(4):672-80. PubMed ID: 26744328
    [TBL] [Abstract][Full Text] [Related]  

  • 11. What genetics tells us about the causes and mechanisms of Parkinson's disease.
    Corti O; Lesage S; Brice A
    Physiol Rev; 2011 Oct; 91(4):1161-218. PubMed ID: 22013209
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Impaired mitochondrial dynamics and function in the pathogenesis of Parkinson's disease.
    Büeler H
    Exp Neurol; 2009 Aug; 218(2):235-46. PubMed ID: 19303005
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mechanisms in dominant parkinsonism: The toxic triangle of LRRK2, alpha-synuclein, and tau.
    Taymans JM; Cookson MR
    Bioessays; 2010 Mar; 32(3):227-235. PubMed ID: 20127702
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Conditional expression of Parkinson's disease-related R1441C LRRK2 in midbrain dopaminergic neurons of mice causes nuclear abnormalities without neurodegeneration.
    Tsika E; Kannan M; Foo CS; Dikeman D; Glauser L; Gellhaar S; Galter D; Knott GW; Dawson TM; Dawson VL; Moore DJ
    Neurobiol Dis; 2014 Nov; 71():345-58. PubMed ID: 25174890
    [TBL] [Abstract][Full Text] [Related]  

  • 15. A Drosophila model for LRRK2-linked parkinsonism.
    Liu Z; Wang X; Yu Y; Li X; Wang T; Jiang H; Ren Q; Jiao Y; Sawa A; Moran T; Ross CA; Montell C; Smith WW
    Proc Natl Acad Sci U S A; 2008 Feb; 105(7):2693-8. PubMed ID: 18258746
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Parkin and defective ubiquitination in Parkinson's disease.
    Dawson TM
    J Neural Transm Suppl; 2006; (70):209-13. PubMed ID: 17017531
    [TBL] [Abstract][Full Text] [Related]  

  • 17. LRRK2 impairs PINK1/Parkin-dependent mitophagy via its kinase activity: pathologic insights into Parkinson's disease.
    Bonello F; Hassoun SM; Mouton-Liger F; Shin YS; Muscat A; Tesson C; Lesage S; Beart PM; Brice A; Krupp J; Corvol JC; Corti O
    Hum Mol Genet; 2019 May; 28(10):1645-1660. PubMed ID: 30629163
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Biochemical and molecular features of LRRK2 and its pathophysiological roles in Parkinson's disease.
    Seol W
    BMB Rep; 2010 Apr; 43(4):233-44. PubMed ID: 20423607
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mitochondrial Calcium Dysregulation Contributes to Dendrite Degeneration Mediated by PD/LBD-Associated LRRK2 Mutants.
    Verma M; Callio J; Otero PA; Sekler I; Wills ZP; Chu CT
    J Neurosci; 2017 Nov; 37(46):11151-11165. PubMed ID: 29038245
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mutant LRRK2 toxicity in neurons depends on LRRK2 levels and synuclein but not kinase activity or inclusion bodies.
    Skibinski G; Nakamura K; Cookson MR; Finkbeiner S
    J Neurosci; 2014 Jan; 34(2):418-33. PubMed ID: 24403142
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 20.