BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

253 related articles for article (PubMed ID: 16354692)

  • 1. Notch activation is an early and critical event during T-Cell leukemogenesis in Ikaros-deficient mice.
    Dumortier A; Jeannet R; Kirstetter P; Kleinmann E; Sellars M; dos Santos NR; Thibault C; Barths J; Ghysdael J; Punt JA; Kastner P; Chan S
    Mol Cell Biol; 2006 Jan; 26(1):209-20. PubMed ID: 16354692
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Ikaros represses the transcriptional response to Notch signaling in T-cell development.
    Kleinmann E; Geimer Le Lay AS; Sellars M; Kastner P; Chan S
    Mol Cell Biol; 2008 Dec; 28(24):7465-75. PubMed ID: 18852286
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Ikaros is a critical target during simultaneous exposure to X-rays and N-ethyl-N-nitrosourea in mouse T-cell lymphomagenesis.
    Hirano S; Kakinuma S; Amasaki Y; Nishimura M; Imaoka T; Fujimoto S; Hino O; Shimada Y
    Int J Cancer; 2013 Jan; 132(2):259-68. PubMed ID: 22684892
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Ikaros regulates Notch target gene expression in developing thymocytes.
    Chari S; Winandy S
    J Immunol; 2008 Nov; 181(9):6265-74. PubMed ID: 18941217
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Ikaros directly represses the notch target gene Hes1 in a leukemia T cell line: implications for CD4 regulation.
    Kathrein KL; Chari S; Winandy S
    J Biol Chem; 2008 Apr; 283(16):10476-84. PubMed ID: 18287091
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Activating Notch1 mutations are an early event in T-cell malignancy of Ikaros point mutant Plastic/+ mice.
    Mantha S; Ward M; McCafferty J; Herron A; Palomero T; Ferrando A; Bank A; Richardson C
    Leuk Res; 2007 Mar; 31(3):321-7. PubMed ID: 16870249
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Cooperation between somatic Ikaros and Notch1 mutations at the inception of T-ALL.
    Sontani Y; Chapman G; Papathanasiou P; Dunwoodie S; Goodnow CC; Hoyne GF
    Leuk Res; 2011 Nov; 35(11):1512-9. PubMed ID: 21840596
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Identification of Notch target genes in uncommitted T-cell progenitors: No direct induction of a T-cell specific gene program.
    Weerkamp F; Luis TC; Naber BA; Koster EE; Jeannotte L; van Dongen JJ; Staal FJ
    Leukemia; 2006 Nov; 20(11):1967-77. PubMed ID: 16990763
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Combined expression of pTalpha and Notch3 in T cell leukemia identifies the requirement of preTCR for leukemogenesis.
    Bellavia D; Campese AF; Checquolo S; Balestri A; Biondi A; Cazzaniga G; Lendahl U; Fehling HJ; Hayday AC; Frati L; von Boehmer H; Gulino A; Screpanti I
    Proc Natl Acad Sci U S A; 2002 Mar; 99(6):3788-93. PubMed ID: 11891328
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Notch target gene deregulation and maintenance of the leukemogenic phenotype do not require RBP-J kappa in Ikaros null mice.
    Chari S; Umetsu SE; Winandy S
    J Immunol; 2010 Jul; 185(1):410-7. PubMed ID: 20511547
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Characterization of the transcriptional expression of Notch-1 signaling pathway members, Deltex and HES-1, in developing mouse thymocytes.
    Choi JW; Pampeno C; Vukmanovic S; Meruelo D
    Dev Comp Immunol; 2002 Jul; 26(6):575-88. PubMed ID: 12031417
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Oncogenic activation of the Notch1 gene by deletion of its promoter in Ikaros-deficient T-ALL.
    Jeannet R; Mastio J; Macias-Garcia A; Oravecz A; Ashworth T; Geimer Le Lay AS; Jost B; Le Gras S; Ghysdael J; Gridley T; Honjo T; Radtke F; Aster JC; Chan S; Kastner P
    Blood; 2010 Dec; 116(25):5443-54. PubMed ID: 20829372
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Alternative promoter usage at the Notch1 locus supports ligand-independent signaling in T cell development and leukemogenesis.
    Gómez-del Arco P; Kashiwagi M; Jackson AF; Naito T; Zhang J; Liu F; Kee B; Vooijs M; Radtke F; Redondo JM; Georgopoulos K
    Immunity; 2010 Nov; 33(5):685-98. PubMed ID: 21093322
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Notch signaling is activated by TLR stimulation and regulates macrophage functions.
    Palaga T; Buranaruk C; Rengpipat S; Fauq AH; Golde TE; Kaufmann SH; Osborne BA
    Eur J Immunol; 2008 Jan; 38(1):174-83. PubMed ID: 18085664
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The tumor suppressor Ikaros shapes the repertoire of notch target genes in T cells.
    Geimer Le Lay AS; Oravecz A; Mastio J; Jung C; Marchal P; Ebel C; Dembélé D; Jost B; Le Gras S; Thibault C; Borggrefe T; Kastner P; Chan S
    Sci Signal; 2014 Mar; 7(317):ra28. PubMed ID: 24643801
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A dominant mutation in the Ikaros gene leads to rapid development of leukemia and lymphoma.
    Winandy S; Wu P; Georgopoulos K
    Cell; 1995 Oct; 83(2):289-99. PubMed ID: 7585946
    [TBL] [Abstract][Full Text] [Related]  

  • 17. NOTCH pathway inactivation promotes bladder cancer progression.
    Maraver A; Fernandez-Marcos PJ; Cash TP; Mendez-Pertuz M; Dueñas M; Maietta P; Martinelli P; Muñoz-Martin M; Martínez-Fernández M; Cañamero M; Roncador G; Martinez-Torrecuadrada JL; Grivas D; de la Pompa JL; Valencia A; Paramio JM; Real FX; Serrano M
    J Clin Invest; 2015 Feb; 125(2):824-30. PubMed ID: 25574842
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Enhanced Notch activation is advantageous but not essential for T cell lymphomagenesis in Id1 transgenic mice.
    Wang HC; Peng V; Zhao Y; Sun XH
    PLoS One; 2012; 7(2):e32944. PubMed ID: 22393458
    [TBL] [Abstract][Full Text] [Related]  

  • 19. SCL, LMO1 and Notch1 reprogram thymocytes into self-renewing cells.
    Gerby B; Tremblay CS; Tremblay M; Rojas-Sutterlin S; Herblot S; Hébert J; Sauvageau G; Lemieux S; Lécuyer E; Veiga DF; Hoang T
    PLoS Genet; 2014 Dec; 10(12):e1004768. PubMed ID: 25522233
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Canonical notch signaling functions as a commitment switch in the epidermal lineage.
    Blanpain C; Lowry WE; Pasolli HA; Fuchs E
    Genes Dev; 2006 Nov; 20(21):3022-35. PubMed ID: 17079689
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.