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5. Ikaros directly represses the notch target gene Hes1 in a leukemia T cell line: implications for CD4 regulation. Kathrein KL; Chari S; Winandy S J Biol Chem; 2008 Apr; 283(16):10476-84. PubMed ID: 18287091 [TBL] [Abstract][Full Text] [Related]
6. Activating Notch1 mutations are an early event in T-cell malignancy of Ikaros point mutant Plastic/+ mice. Mantha S; Ward M; McCafferty J; Herron A; Palomero T; Ferrando A; Bank A; Richardson C Leuk Res; 2007 Mar; 31(3):321-7. PubMed ID: 16870249 [TBL] [Abstract][Full Text] [Related]
7. Cooperation between somatic Ikaros and Notch1 mutations at the inception of T-ALL. Sontani Y; Chapman G; Papathanasiou P; Dunwoodie S; Goodnow CC; Hoyne GF Leuk Res; 2011 Nov; 35(11):1512-9. PubMed ID: 21840596 [TBL] [Abstract][Full Text] [Related]
8. Identification of Notch target genes in uncommitted T-cell progenitors: No direct induction of a T-cell specific gene program. Weerkamp F; Luis TC; Naber BA; Koster EE; Jeannotte L; van Dongen JJ; Staal FJ Leukemia; 2006 Nov; 20(11):1967-77. PubMed ID: 16990763 [TBL] [Abstract][Full Text] [Related]
9. Combined expression of pTalpha and Notch3 in T cell leukemia identifies the requirement of preTCR for leukemogenesis. Bellavia D; Campese AF; Checquolo S; Balestri A; Biondi A; Cazzaniga G; Lendahl U; Fehling HJ; Hayday AC; Frati L; von Boehmer H; Gulino A; Screpanti I Proc Natl Acad Sci U S A; 2002 Mar; 99(6):3788-93. PubMed ID: 11891328 [TBL] [Abstract][Full Text] [Related]
10. Notch target gene deregulation and maintenance of the leukemogenic phenotype do not require RBP-J kappa in Ikaros null mice. Chari S; Umetsu SE; Winandy S J Immunol; 2010 Jul; 185(1):410-7. PubMed ID: 20511547 [TBL] [Abstract][Full Text] [Related]
11. Characterization of the transcriptional expression of Notch-1 signaling pathway members, Deltex and HES-1, in developing mouse thymocytes. Choi JW; Pampeno C; Vukmanovic S; Meruelo D Dev Comp Immunol; 2002 Jul; 26(6):575-88. PubMed ID: 12031417 [TBL] [Abstract][Full Text] [Related]
12. Oncogenic activation of the Notch1 gene by deletion of its promoter in Ikaros-deficient T-ALL. Jeannet R; Mastio J; Macias-Garcia A; Oravecz A; Ashworth T; Geimer Le Lay AS; Jost B; Le Gras S; Ghysdael J; Gridley T; Honjo T; Radtke F; Aster JC; Chan S; Kastner P Blood; 2010 Dec; 116(25):5443-54. PubMed ID: 20829372 [TBL] [Abstract][Full Text] [Related]
13. Alternative promoter usage at the Notch1 locus supports ligand-independent signaling in T cell development and leukemogenesis. Gómez-del Arco P; Kashiwagi M; Jackson AF; Naito T; Zhang J; Liu F; Kee B; Vooijs M; Radtke F; Redondo JM; Georgopoulos K Immunity; 2010 Nov; 33(5):685-98. PubMed ID: 21093322 [TBL] [Abstract][Full Text] [Related]
14. Notch signaling is activated by TLR stimulation and regulates macrophage functions. Palaga T; Buranaruk C; Rengpipat S; Fauq AH; Golde TE; Kaufmann SH; Osborne BA Eur J Immunol; 2008 Jan; 38(1):174-83. PubMed ID: 18085664 [TBL] [Abstract][Full Text] [Related]
15. The tumor suppressor Ikaros shapes the repertoire of notch target genes in T cells. Geimer Le Lay AS; Oravecz A; Mastio J; Jung C; Marchal P; Ebel C; Dembélé D; Jost B; Le Gras S; Thibault C; Borggrefe T; Kastner P; Chan S Sci Signal; 2014 Mar; 7(317):ra28. PubMed ID: 24643801 [TBL] [Abstract][Full Text] [Related]
16. A dominant mutation in the Ikaros gene leads to rapid development of leukemia and lymphoma. Winandy S; Wu P; Georgopoulos K Cell; 1995 Oct; 83(2):289-99. PubMed ID: 7585946 [TBL] [Abstract][Full Text] [Related]
17. NOTCH pathway inactivation promotes bladder cancer progression. Maraver A; Fernandez-Marcos PJ; Cash TP; Mendez-Pertuz M; Dueñas M; Maietta P; Martinelli P; Muñoz-Martin M; Martínez-Fernández M; Cañamero M; Roncador G; Martinez-Torrecuadrada JL; Grivas D; de la Pompa JL; Valencia A; Paramio JM; Real FX; Serrano M J Clin Invest; 2015 Feb; 125(2):824-30. PubMed ID: 25574842 [TBL] [Abstract][Full Text] [Related]
18. Enhanced Notch activation is advantageous but not essential for T cell lymphomagenesis in Id1 transgenic mice. Wang HC; Peng V; Zhao Y; Sun XH PLoS One; 2012; 7(2):e32944. PubMed ID: 22393458 [TBL] [Abstract][Full Text] [Related]