BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

69 related articles for article (PubMed ID: 16356459)

  • 1. Comparative analysis of various in vitro COT kinase assay formats and their applications in inhibitor identification and characterization.
    Jia Y; Quinn CM; Clabbers A; Talanian R; Xu Y; Wishart N; Allen H
    Anal Biochem; 2006 Mar; 350(2):268-76. PubMed ID: 16356459
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Purification and kinetic characterization of recombinant human mitogen-activated protein kinase kinase kinase COT and the complexes with its cellular partner NF-kappa B1 p105.
    Jia Y; Quinn CM; Bump NJ; Clark KM; Clabbers A; Hardman J; Gagnon A; Kamens J; Tomlinson MJ; Wishart N; Allen H
    Arch Biochem Biophys; 2005 Sep; 441(1):64-74. PubMed ID: 16087150
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Identification of a selective thieno[2,3-c]pyridine inhibitor of COT kinase and TNF-alpha production.
    Cusack K; Allen H; Bischoff A; Clabbers A; Dixon R; Fix-Stenzel S; Friedman M; Gaumont Y; George D; Gordon T; Grongsaard P; Janssen B; Jia Y; Moskey M; Quinn C; Salmeron A; Thomas C; Wallace G; Wishart N; Yu Z
    Bioorg Med Chem Lett; 2009 Mar; 19(6):1722-5. PubMed ID: 19217782
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Luteolin, a novel natural inhibitor of tumor progression locus 2 serine/threonine kinase, inhibits tumor necrosis factor-alpha-induced cyclooxygenase-2 expression in JB6 mouse epidermis cells.
    Kim JE; Son JE; Jang YJ; Lee DE; Kang NJ; Jung SK; Heo YS; Lee KW; Lee HJ
    J Pharmacol Exp Ther; 2011 Sep; 338(3):1013-22. PubMed ID: 21705614
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Development of a 1-microl scale assay for mitogen-activated kinase kinase 7 using 2-D fluorescence intensity distribution analysis anisotropy.
    Wright PA; Boyd HF; Bethell RC; Busch M; Gribbon P; Kraemer J; Lopez-Calle E; Mander TH; Winkler D; Benson N
    J Biomol Screen; 2002 Oct; 7(5):419-28. PubMed ID: 14599357
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Cancer Osaka thyroid (Cot) phosphorylates Polo-like kinase (PLK1) at Ser137 but not at Thr210.
    Wu B; Jiang P; Mu Y; Wilmouth RC
    Biol Chem; 2009 Dec; 390(12):1271-7. PubMed ID: 19804365
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Involvement of Cot/Tp12 in bone loss during periodontitis.
    Ohnishi T; Okamoto A; Kakimoto K; Bandow K; Chiba N; Matsuguchi T
    J Dent Res; 2010 Feb; 89(2):192-7. PubMed ID: 20089988
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Current status of HTRF(®) technology in kinase assays.
    Jia Y
    Expert Opin Drug Discov; 2008 Dec; 3(12):1461-74. PubMed ID: 23506109
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Discovery and characterization of non-ATP site inhibitors of the mitogen activated protein (MAP) kinases.
    Comess KM; Sun C; Abad-Zapatero C; Goedken ER; Gum RJ; Borhani DW; Argiriadi M; Groebe DR; Jia Y; Clampit JE; Haasch DL; Smith HT; Wang S; Song D; Coen ML; Cloutier TE; Tang H; Cheng X; Quinn C; Liu B; Xin Z; Liu G; Fry EH; Stoll V; Ng TI; Banach D; Marcotte D; Burns DJ; Calderwood DJ; Hajduk PJ
    ACS Chem Biol; 2011 Mar; 6(3):234-44. PubMed ID: 21090814
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Kinetic characterization of novel pyrazole TGF-beta receptor I kinase inhibitors and their blockade of the epithelial-mesenchymal transition.
    Peng SB; Yan L; Xia X; Watkins SA; Brooks HB; Beight D; Herron DK; Jones ML; Lampe JW; McMillen WT; Mort N; Sawyer JS; Yingling JM
    Biochemistry; 2005 Feb; 44(7):2293-304. PubMed ID: 15709742
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Designing in vitro assays for drug discovery: a study with the human MAP3 kinase COT.
    Jia Y; Quinn CM; Talanian RV
    Expert Opin Drug Discov; 2007 Jul; 2(7):909-15. PubMed ID: 23484811
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Fluorescence polarization competition immunoassay for tyrosine kinases.
    Seethala R
    Methods; 2000 Sep; 22(1):61-70. PubMed ID: 11020319
    [TBL] [Abstract][Full Text] [Related]  

  • 13. High-throughput, cell-free, liposome-based approach for assessing in vitro activity of lipid kinases.
    Demian DJ; Clugston SL; Foster MM; Rameh L; Sarkes D; Townson SA; Yang L; Zhang M; Charlton ME
    J Biomol Screen; 2009 Aug; 14(7):838-44. PubMed ID: 19641220
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Homogeneous proximity tyrosine kinase assays: scintillation proximity assay versus homogeneous time-resolved fluorescence.
    Park YW; Cummings RT; Wu L; Zheng S; Cameron PM; Woods A; Zaller DM; Marcy AI; Hermes JD
    Anal Biochem; 1999 Apr; 269(1):94-104. PubMed ID: 10094779
    [TBL] [Abstract][Full Text] [Related]  

  • 15. TRAF6 and Src kinase activity regulates Cot activation by IL-1.
    Rodríguez C; Pozo M; Nieto E; Fernández M; Alemany S
    Cell Signal; 2006 Sep; 18(9):1376-85. PubMed ID: 16371247
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Evaluating the utility of the HTRF Transcreener ADP assay technology: a comparison with the standard HTRF assay technology.
    Hong L; Quinn CM; Jia Y
    Anal Biochem; 2009 Aug; 391(1):31-8. PubMed ID: 19406097
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Serine/threonine kinase, Cot/Tpl2, regulates renal cell apoptosis in ischaemia/reperfusion injury.
    Yaomura T; Tsuboi N; Urahama Y; Hobo A; Sugimoto K; Miyoshi J; Matsuguchi T; Reiji K; Matsuo S; Yuzawa Y
    Nephrology (Carlton); 2008 Oct; 13(5):397-404. PubMed ID: 18518937
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Utilization of fluorescence polarization and time resolved fluorescence resonance energy transfer assay formats for SAR studies: Src kinase as a model system.
    Newman M; Josiah S
    J Biomol Screen; 2004 Sep; 9(6):525-32. PubMed ID: 15452339
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Discovery of thieno[2,3-c]pyridines as potent COT inhibitors.
    George D; Friedman M; Allen H; Argiriadi M; Barberis C; Bischoff A; Clabbers A; Cusack K; Dixon R; Fix-Stenzel S; Gordon T; Janssen B; Jia Y; Moskey M; Quinn C; Salmeron JA; Wishart N; Woller K; Yu Z
    Bioorg Med Chem Lett; 2008 Sep; 18(18):4952-5. PubMed ID: 18755587
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Development and applications of a broad-coverage, TR-FRET-based kinase binding assay platform.
    Lebakken CS; Riddle SM; Singh U; Frazee WJ; Eliason HC; Gao Y; Reichling LJ; Marks BD; Vogel KW
    J Biomol Screen; 2009 Sep; 14(8):924-35. PubMed ID: 19564447
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 4.