BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

295 related articles for article (PubMed ID: 16357143)

  • 1. CDC4 mutations occur in a subset of colorectal cancers but are not predicted to cause loss of function and are not associated with chromosomal instability.
    Kemp Z; Rowan A; Chambers W; Wortham N; Halford S; Sieber O; Mortensen N; von Herbay A; Gunther T; Ilyas M; Tomlinson I
    Cancer Res; 2005 Dec; 65(24):11361-6. PubMed ID: 16357143
    [TBL] [Abstract][Full Text] [Related]  

  • 2. SMAD4 mutations in colorectal cancer probably occur before chromosomal instability, but after divergence of the microsatellite instability pathway.
    Woodford-Richens KL; Rowan AJ; Gorman P; Halford S; Bicknell DC; Wasan HS; Roylance RR; Bodmer WF; Tomlinson IP
    Proc Natl Acad Sci U S A; 2001 Aug; 98(17):9719-23. PubMed ID: 11481457
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Somatic mutations of the CDC4 (FBXW7) gene in hereditary colorectal tumors.
    Miyaki M; Yamaguchi T; Iijima T; Takahashi K; Matsumoto H; Mori T
    Oncology; 2009; 76(6):430-4. PubMed ID: 19420964
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Fbxw7/Cdc4 is a p53-dependent, haploinsufficient tumour suppressor gene.
    Mao JH; Perez-Losada J; Wu D; Delrosario R; Tsunematsu R; Nakayama KI; Brown K; Bryson S; Balmain A
    Nature; 2004 Dec; 432(7018):775-9. PubMed ID: 15592418
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Colorectal cancer without high microsatellite instability and chromosomal instability--an alternative genetic pathway to human colorectal cancer.
    Tang R; Changchien CR; Wu MC; Fan CW; Liu KW; Chen JS; Chien HT; Hsieh LL
    Carcinogenesis; 2004 May; 25(5):841-6. PubMed ID: 14729584
    [TBL] [Abstract][Full Text] [Related]  

  • 6. High copy amplification of the Aurora-A gene is associated with chromosomal instability phenotype in human colorectal cancers.
    Nishida N; Nagasaka T; Kashiwagi K; Boland CR; Goel A
    Cancer Biol Ther; 2007 Apr; 6(4):525-33. PubMed ID: 17457043
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Relationship between genetic alterations and prognosis in sporadic colorectal cancer.
    Chang SC; Lin JK; Yang SH; Wang HS; Li AF; Chi CW
    Int J Cancer; 2006 Apr; 118(7):1721-7. PubMed ID: 16231316
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Loss of CDC4/FBXW7 in gastric carcinoma.
    Milne AN; Leguit R; Corver WE; Morsink FH; Polak M; de Leng WW; Carvalho R; Offerhaus GJ
    Cell Oncol; 2010; 32(5-6):347-59. PubMed ID: 20448329
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Frequent p53 gene mutations in serrated adenomas of the colorectum.
    Hiyama T; Yokozaki H; Shimamoto F; Haruma K; Yasui W; Kajiyama G; Tahara E
    J Pathol; 1998 Oct; 186(2):131-9. PubMed ID: 9924427
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Copy number of the Adenomatous Polyposis Coli gene is not always neutral in sporadic colorectal cancers with loss of heterozygosity for the gene.
    Zauber P; Marotta S; Sabbath-Solitare M
    BMC Cancer; 2016 Mar; 16():213. PubMed ID: 26970738
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Refining molecular analysis in the pathways of colorectal carcinogenesis.
    Rowan A; Halford S; Gaasenbeek M; Kemp Z; Sieber O; Volikos E; Douglas E; Fiegler H; Carter N; Talbot I; Silver A; Tomlinson I
    Clin Gastroenterol Hepatol; 2005 Nov; 3(11):1115-23. PubMed ID: 16271343
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Control of genomic instability and epithelial tumor development by the p53-Fbxw7/Cdc4 pathway.
    Perez-Losada J; Mao JH; Balmain A
    Cancer Res; 2005 Aug; 65(15):6488-92. PubMed ID: 16061623
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Comprehensive mutation analysis in colorectal flat adenomas.
    Voorham QJ; Carvalho B; Spiertz AJ; Claes B; Mongera S; van Grieken NC; Grabsch H; Kliment M; Rembacken B; van de Wiel MA; Quirke P; Mulder CJ; Lambrechts D; van Engeland M; Meijer GA
    PLoS One; 2012; 7(7):e41963. PubMed ID: 22848674
    [TBL] [Abstract][Full Text] [Related]  

  • 14. FBXW7 mutation in adult T-cell and B-cell acute lymphocytic leukemias.
    Song JH; Schnittke N; Zaat A; Walsh CS; Miller CW
    Leuk Res; 2008 Nov; 32(11):1751-5. PubMed ID: 18485478
    [TBL] [Abstract][Full Text] [Related]  

  • 15. FBXW7/hCDC4 is a general tumor suppressor in human cancer.
    Akhoondi S; Sun D; von der Lehr N; Apostolidou S; Klotz K; Maljukova A; Cepeda D; Fiegl H; Dafou D; Marth C; Mueller-Holzner E; Corcoran M; Dagnell M; Nejad SZ; Nayer BN; Zali MR; Hansson J; Egyhazi S; Petersson F; Sangfelt P; Nordgren H; Grander D; Reed SI; Widschwendter M; Sangfelt O; Spruck C
    Cancer Res; 2007 Oct; 67(19):9006-12. PubMed ID: 17909001
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Investigation of the atypical FBXW7 mutation spectrum in human tumours by conditional expression of a heterozygous propellor tip missense allele in the mouse intestines.
    Davis H; Lewis A; Behrens A; Tomlinson I
    Gut; 2014 May; 63(5):792-9. PubMed ID: 23676439
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Analysis of chromosomal instability in human colorectal adenomas with two mutational hits at APC.
    Sieber OM; Heinimann K; Gorman P; Lamlum H; Crabtree M; Simpson CA; Davies D; Neale K; Hodgson SV; Roylance RR; Phillips RK; Bodmer WF; Tomlinson IP
    Proc Natl Acad Sci U S A; 2002 Dec; 99(26):16910-5. PubMed ID: 12486240
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mutations in the p53 and Ki-ras genes, microsatellite instability and site of tumor origin in colorectal cancer.
    Catalano T; Curia MC; Aceto G; Verginelli F; Cascinu S; Cama A; Mariani-Costantini R; Teti D; Battista P
    Oncol Rep; 2005 Sep; 14(3):625-31. PubMed ID: 16077965
    [TBL] [Abstract][Full Text] [Related]  

  • 19. DNA alterations of microsatellite DNA, p53, APC and K-ras in Chinese colorectal cancer patients.
    Xu XM; Qian JC; Cai Z; Tang T; Wang P; Zhang KH; Deng ZL; Cai JP
    Eur J Clin Invest; 2012 Jul; 42(7):751-9. PubMed ID: 22324744
    [TBL] [Abstract][Full Text] [Related]  

  • 20. FBXW7-mutated colorectal cancer cells exhibit aberrant expression of phosphorylated-p53 at Serine-15.
    Li N; Lorenzi F; Kalakouti E; Normatova M; Babaei-Jadidi R; Tomlinson I; Nateri AS
    Oncotarget; 2015 Apr; 6(11):9240-56. PubMed ID: 25860929
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 15.