240 related articles for article (PubMed ID: 16360193)
1. Parallel synthesis of 5-cyano-6-aryl-2-thiouracil derivatives as inhibitors for hepatitis C viral NS5B RNA-dependent RNA polymerase.
Ding Y; Girardet JL; Smith KL; Larson G; Prigaro B; Wu JZ; Yao N
Bioorg Chem; 2006 Feb; 34(1):26-38. PubMed ID: 16360193
[TBL] [Abstract][Full Text] [Related]
2. Non-nucleoside inhibitors of the hepatitis C virus NS5B polymerase: discovery and preliminary SAR of benzimidazole derivatives.
Beaulieu PL; Bös M; Bousquet Y; Fazal G; Gauthier J; Gillard J; Goulet S; LaPlante S; Poupart MA; Lefebvre S; McKercher G; Pellerin C; Austel V; Kukolj G
Bioorg Med Chem Lett; 2004 Jan; 14(1):119-24. PubMed ID: 14684311
[TBL] [Abstract][Full Text] [Related]
3. 2-(3-Thienyl)-5,6-dihydroxypyrimidine-4-carboxylic acids as inhibitors of HCV NS5B RdRp.
Pacini B; Avolio S; Ercolani C; Koch U; Migliaccio G; Narjes F; Pacini L; Tomei L; Harper S
Bioorg Med Chem Lett; 2009 Nov; 19(21):6245-9. PubMed ID: 19800789
[TBL] [Abstract][Full Text] [Related]
4. Non-nucleoside inhibitors of the hepatitis C virus NS5B RNA-dependant RNA polymerase: 2-aryl-3-heteroaryl-1,3-thiazolidin-4-one derivatives.
Rawal RK; Katti SB; Kaushik-Basu N; Arora P; Pan Z
Bioorg Med Chem Lett; 2008 Dec; 18(23):6110-4. PubMed ID: 18947995
[TBL] [Abstract][Full Text] [Related]
5. Preparation and biological evaluation of 1'-cyano-2'-C-methyl pyrimidine nucleosides as HCV NS5B polymerase inhibitors.
Mish MR; Cho A; Kirschberg T; Xu J; Zonte CS; Fenaux M; Park Y; Babusis D; Feng JY; Ray AS; Kim CU
Bioorg Med Chem Lett; 2014 Jul; 24(14):3092-5. PubMed ID: 24907145
[TBL] [Abstract][Full Text] [Related]
6. Aryl uracil inhibitors of hepatitis C virus NS5B polymerase: synthesis and characterization of analogs with a fused 5,6-bicyclic ring motif.
Krueger AC; Randolph JT; DeGoey DA; Donner PL; Flentge CA; Hutchinson DK; Liu D; Motter CE; Rockway TW; Wagner R; Beno DW; Koev G; Lim HB; Beyer JM; Mondal R; Liu Y; Kati WM; Longenecker KL; Molla A; Stewart KD; Maring CJ
Bioorg Med Chem Lett; 2013 Jun; 23(12):3487-90. PubMed ID: 23664214
[TBL] [Abstract][Full Text] [Related]
7. Parallel synthesis of pteridine derivatives as potent inhibitors for hepatitis C virus NS5B RNA-dependent RNA polymerase.
Ding Y; Girardet JL; Smith KL; Larson G; Prigaro B; Lai VC; Zhong W; Wu JZ
Bioorg Med Chem Lett; 2005 Feb; 15(3):675-8. PubMed ID: 15664835
[TBL] [Abstract][Full Text] [Related]
8. Synthesis and antiviral properties of novel tetracyclic nucleoside inhibitors of hepatitis C NS5B polymerase.
Di Francesco ME; Avolio S; Dessole G; Koch U; Pompei M; Pucci V; Rowley M; Summa V
Nucleosides Nucleotides Nucleic Acids; 2012; 31(8):592-607. PubMed ID: 22908950
[TBL] [Abstract][Full Text] [Related]
9. Chemical genetics-based discovery of indole derivatives as HCV NS5B polymerase inhibitors.
Jin G; Lee S; Choi M; Son S; Kim GW; Oh JW; Lee C; Lee K
Eur J Med Chem; 2014 Mar; 75():413-25. PubMed ID: 24561671
[TBL] [Abstract][Full Text] [Related]
10. The discovery of pyrano[3,4-b]indole-based allosteric inhibitors of HCV NS5B polymerase with in vivo activity.
Laporte MG; Jackson RW; Draper TL; Gaboury JA; Galie K; Herbertz T; Hussey AR; Rippin SR; Benetatos CA; Chunduru SK; Christensen JS; Coburn GA; Rizzo CJ; Rhodes G; O'Connell J; Howe AY; Mansour TS; Collett MS; Pevear DC; Young DC; Gao T; Tyrrell DL; Kneteman NM; Burns CJ; Condon SM
ChemMedChem; 2008 Oct; 3(10):1508-15. PubMed ID: 18729128
[No Abstract] [Full Text] [Related]
11. Novel nonnucleoside inhibitor of hepatitis C virus RNA-dependent RNA polymerase.
Howe AY; Bloom J; Baldick CJ; Benetatos CA; Cheng H; Christensen JS; Chunduru SK; Coburn GA; Feld B; Gopalsamy A; Gorczyca WP; Herrmann S; Johann S; Jiang X; Kimberland ML; Krisnamurthy G; Olson M; Orlowski M; Swanberg S; Thompson I; Thorn M; Del Vecchio A; Young DC; van Zeijl M; Ellingboe JW; Upeslacis J; Collett M; Mansour TS; O'Connell JF
Antimicrob Agents Chemother; 2004 Dec; 48(12):4813-21. PubMed ID: 15561861
[TBL] [Abstract][Full Text] [Related]
12. 5,5'- and 6,6'-dialkyl-5,6-dihydro-1H-pyridin-2-ones as potent inhibitors of HCV NS5B polymerase.
Ellis DA; Blazel JK; Tran CV; Ruebsam F; Murphy DE; Li LS; Zhao J; Zhou Y; McGuire HM; Xiang AX; Webber SE; Zhao Q; Han Q; Kissinger CR; Lardy M; Gobbi A; Showalter RE; Shah AM; Tsan M; Patel RA; LeBrun LA; Kamran R; Bartkowski DM; Nolan TG; Norris DA; Sergeeva MV; Kirkovsky L
Bioorg Med Chem Lett; 2009 Nov; 19(21):6047-52. PubMed ID: 19796938
[TBL] [Abstract][Full Text] [Related]
13. Design and synthesis of lactam-thiophene carboxylic acids as potent hepatitis C virus polymerase inhibitors.
Barnes-Seeman D; Boiselle C; Capacci-Daniel C; Chopra R; Hoffmaster K; Jones CT; Kato M; Lin K; Ma S; Pan G; Shu L; Wang J; Whiteman L; Xu M; Zheng R; Fu J
Bioorg Med Chem Lett; 2014 Aug; 24(16):3979-85. PubMed ID: 24986660
[TBL] [Abstract][Full Text] [Related]
14. Novel 4-thiazolidinones as non-nucleoside inhibitors of hepatitis C virus NS5B RNA-dependent RNA polymerase.
Çakir G; Küçükgüzel İ; Guhamazumder R; Tatar E; Manvar D; Basu A; Patel BA; Zia J; Talele TT; Kaushik-Basu N
Arch Pharm (Weinheim); 2015 Jan; 348(1):10-22. PubMed ID: 25449674
[TBL] [Abstract][Full Text] [Related]
15. Specific inhibitors of HCV polymerase identified using an NS5B with lower affinity for template/primer substrate.
McKercher G; Beaulieu PL; Lamarre D; LaPlante S; Lefebvre S; Pellerin C; Thauvette L; Kukolj G
Nucleic Acids Res; 2004; 32(2):422-31. PubMed ID: 14739234
[TBL] [Abstract][Full Text] [Related]
16. [Non-hydrolysable analogs of inorganic pyrophosphate as inhibitors of hepatitis C virus RNA-dependent RNA-polymerase].
Ianvarev DV; Korovina AN; Usanov NN; Kochetkov SN
Bioorg Khim; 2012; 38(2):257-62. PubMed ID: 22792731
[TBL] [Abstract][Full Text] [Related]
17. Recent advances in discovery and development of promising therapeutics against hepatitis C virus NS5B RNA-dependent RNA polymerase.
Wu JZ; Yao N; Walker M; Hong Z
Mini Rev Med Chem; 2005 Dec; 5(12):1103-12. PubMed ID: 16375756
[TBL] [Abstract][Full Text] [Related]
18. Further SAR studies on novel small molecule inhibitors of the hepatitis C (HCV) NS5B polymerase.
Reddy TJ; Chan L; Turcotte N; Proulx M; Pereira OZ; Das SK; Siddiqui A; Wang W; Poisson C; Yannopoulos CG; Bilimoria D; L'Heureux L; Alaoui HM; Nguyen-Ba N
Bioorg Med Chem Lett; 2003 Oct; 13(19):3341-4. PubMed ID: 12951122
[TBL] [Abstract][Full Text] [Related]
19. Synthesis of new 4,5-dihydrofuranoindoles and their evaluation as HCV NS5B polymerase inhibitors.
Velázquez F; Venkatraman S; Lesburg CA; Duca J; Rosenblum SB; Kozlowski JA; Njoroge FG
Org Lett; 2012 Jan; 14(2):556-9. PubMed ID: 22220815
[TBL] [Abstract][Full Text] [Related]
20. 1,5-benzodiazepines, a novel class of hepatitis C virus polymerase nonnucleoside inhibitors.
Nyanguile O; Pauwels F; Van den Broeck W; Boutton CW; Quirynen L; Ivens T; van der Helm L; Vandercruyssen G; Mostmans W; Delouvroy F; Dehertogh P; Cummings MD; Bonfanti JF; Simmen KA; Raboisson P
Antimicrob Agents Chemother; 2008 Dec; 52(12):4420-31. PubMed ID: 18852280
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
