BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

210 related articles for article (PubMed ID: 16361258)

  • 1. 6-hydroxydopamine-induced apoptosis is mediated via extracellular auto-oxidation and caspase 3-dependent activation of protein kinase Cdelta.
    Hanrott K; Gudmunsen L; O'Neill MJ; Wonnacott S
    J Biol Chem; 2006 Mar; 281(9):5373-82. PubMed ID: 16361258
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Caspase-3-dependent proteolytic cleavage of protein kinase Cdelta is essential for oxidative stress-mediated dopaminergic cell death after exposure to methylcyclopentadienyl manganese tricarbonyl.
    Anantharam V; Kitazawa M; Wagner J; Kaul S; Kanthasamy AG
    J Neurosci; 2002 Mar; 22(5):1738-51. PubMed ID: 11880503
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Dieldrin induces apoptosis by promoting caspase-3-dependent proteolytic cleavage of protein kinase Cdelta in dopaminergic cells: relevance to oxidative stress and dopaminergic degeneration.
    Kitazawa M; Anantharam V; Kanthasamy AG
    Neuroscience; 2003; 119(4):945-64. PubMed ID: 12831855
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Vanadium induces dopaminergic neurotoxicity via protein kinase Cdelta dependent oxidative signaling mechanisms: relevance to etiopathogenesis of Parkinson's disease.
    Afeseh Ngwa H; Kanthasamy A; Anantharam V; Song C; Witte T; Houk R; Kanthasamy AG
    Toxicol Appl Pharmacol; 2009 Oct; 240(2):273-85. PubMed ID: 19646462
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Dopaminergic neurotoxicant 6-OHDA induces oxidative damage through proteolytic activation of PKCδ in cell culture and animal models of Parkinson's disease.
    Latchoumycandane C; Anantharam V; Jin H; Kanthasamy A; Kanthasamy A
    Toxicol Appl Pharmacol; 2011 Nov; 256(3):314-23. PubMed ID: 21846476
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Blockade of PKCdelta proteolytic activation by loss of function mutants rescues mesencephalic dopaminergic neurons from methylcyclopentadienyl manganese tricarbonyl (MMT)-induced apoptotic cell death.
    Anantharam V; Kitazawa M; Latchoumycandane C; Kanthasamy A; Kanthasamy AG
    Ann N Y Acad Sci; 2004 Dec; 1035():271-89. PubMed ID: 15681813
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Protein kinase Cdelta is a key downstream mediator of manganese-induced apoptosis in dopaminergic neuronal cells.
    Latchoumycandane C; Anantharam V; Kitazawa M; Yang Y; Kanthasamy A; Kanthasamy AG
    J Pharmacol Exp Ther; 2005 Apr; 313(1):46-55. PubMed ID: 15608081
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Differential activation of PKC delta in the substantia nigra of rats following striatal or nigral 6-hydroxydopamine lesions.
    Hanrott K; Murray TK; Orfali Z; Ward M; Finlay C; O'Neill MJ; Wonnacott S
    Eur J Neurosci; 2008 Mar; 27(5):1086-96. PubMed ID: 18312582
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Tyrosine phosphorylation regulates the proteolytic activation of protein kinase Cdelta in dopaminergic neuronal cells.
    Kaul S; Anantharam V; Yang Y; Choi CJ; Kanthasamy A; Kanthasamy AG
    J Biol Chem; 2005 Aug; 280(31):28721-30. PubMed ID: 15961393
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Environmental neurotoxin dieldrin induces apoptosis via caspase-3-dependent proteolytic activation of protein kinase C delta (PKCdelta): Implications for neurodegeneration in Parkinson's disease.
    Kanthasamy AG; Kitazawa M; Yang Y; Anantharam V; Kanthasamy A
    Mol Brain; 2008 Oct; 1():12. PubMed ID: 18945348
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Phosphorylation of p38 MAPK induced by oxidative stress is linked to activation of both caspase-8- and -9-mediated apoptotic pathways in dopaminergic neurons.
    Choi WS; Eom DS; Han BS; Kim WK; Han BH; Choi EJ; Oh TH; Markelonis GJ; Cho JW; Oh YJ
    J Biol Chem; 2004 May; 279(19):20451-60. PubMed ID: 14993216
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Intracellular signaling pathways involved in post-mitotic dopaminergic PC12 cell death induced by 6-hydroxydopamine.
    Rodriguez-Blanco J; Martín V; Herrera F; García-Santos G; Antolín I; Rodriguez C
    J Neurochem; 2008 Oct; 107(1):127-40. PubMed ID: 18665912
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Caspase-3 dependent proteolytic activation of protein kinase C delta mediates and regulates 1-methyl-4-phenylpyridinium (MPP+)-induced apoptotic cell death in dopaminergic cells: relevance to oxidative stress in dopaminergic degeneration.
    Kaul S; Kanthasamy A; Kitazawa M; Anantharam V; Kanthasamy AG
    Eur J Neurosci; 2003 Sep; 18(6):1387-401. PubMed ID: 14511319
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Activation of protein kinase C delta by proteolytic cleavage contributes to manganese-induced apoptosis in dopaminergic cells: protective role of Bcl-2.
    Kitazawa M; Anantharam V; Yang Y; Hirata Y; Kanthasamy A; Kanthasamy AG
    Biochem Pharmacol; 2005 Jan; 69(1):133-46. PubMed ID: 15588722
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Proteasome inhibitor-induced apoptosis is mediated by positive feedback amplification of PKCdelta proteolytic activation and mitochondrial translocation.
    Sun F; Kanthasamy A; Song C; Yang Y; Anantharam V; Kanthasamy AG
    J Cell Mol Med; 2008 Dec; 12(6A):2467-81. PubMed ID: 18298651
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Baicalein attenuates 6-hydroxydopamine-induced neurotoxicity in SH-SY5Y cells.
    Lee HJ; Noh YH; Lee DY; Kim YS; Kim KY; Chung YH; Lee WB; Kim SS
    Eur J Cell Biol; 2005 Nov; 84(11):897-905. PubMed ID: 16323286
    [TBL] [Abstract][Full Text] [Related]  

  • 17. [Phosphorylation of PKCdelta participates in the toxicity of 6-hydroxydopamine on dopaminergic neuroblastoma cell].
    Fan Y; Zhang YN; Zhang YQ; Teng ZY; Li ZW; Wu XW; Li HL
    Zhonghua Yi Xue Za Zhi; 2006 Dec; 86(45):3173-6. PubMed ID: 17313780
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Protein kinase C delta mediated cytotoxicity of 6-Hydroxydopamine via sustained extracellular signal-regulated kinase 1/2 activation in PC12 cells.
    Fan Y; Li J; Zhang YQ; Jiang LH; Zhang YN; Yan CQ
    Neurol Res; 2014 Jan; 36(1):53-64. PubMed ID: 24107416
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Role of proteolytic activation of protein kinase Cdelta in oxidative stress-induced apoptosis.
    Kanthasamy AG; Kitazawa M; Kanthasamy A; Anantharam V
    Antioxid Redox Signal; 2003 Oct; 5(5):609-20. PubMed ID: 14580317
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Proteolytic activation of proapoptotic kinase protein kinase Cδ by tumor necrosis factor α death receptor signaling in dopaminergic neurons during neuroinflammation.
    Gordon R; Anantharam V; Kanthasamy AG; Kanthasamy A
    J Neuroinflammation; 2012 Apr; 9():82. PubMed ID: 22540228
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.