BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

341 related articles for article (PubMed ID: 16365303)

  • 1. Brain estrogen deficiency accelerates Abeta plaque formation in an Alzheimer's disease animal model.
    Yue X; Lu M; Lancaster T; Cao P; Honda S; Staufenbiel M; Harada N; Zhong Z; Shen Y; Li R
    Proc Natl Acad Sci U S A; 2005 Dec; 102(52):19198-203. PubMed ID: 16365303
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Genetic targeting aromatase in male amyloid precursor protein transgenic mice down-regulates beta-secretase (BACE1) and prevents Alzheimer-like pathology and cognitive impairment.
    McAllister C; Long J; Bowers A; Walker A; Cao P; Honda S; Harada N; Staufenbiel M; Shen Y; Li R
    J Neurosci; 2010 May; 30(21):7326-34. PubMed ID: 20505099
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Diet-induced insulin resistance promotes amyloidosis in a transgenic mouse model of Alzheimer's disease.
    Ho L; Qin W; Pompl PN; Xiang Z; Wang J; Zhao Z; Peng Y; Cambareri G; Rocher A; Mobbs CV; Hof PR; Pasinetti GM
    FASEB J; 2004 May; 18(7):902-4. PubMed ID: 15033922
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Brain endogenous estrogen levels determine responses to estrogen replacement therapy via regulation of BACE1 and NEP in female Alzheimer's transgenic mice.
    Li R; He P; Cui J; Staufenbiel M; Harada N; Shen Y
    Mol Neurobiol; 2013 Jun; 47(3):857-67. PubMed ID: 23180279
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Amyloid beta peptide load is correlated with increased beta-secretase activity in sporadic Alzheimer's disease patients.
    Li R; Lindholm K; Yang LB; Yue X; Citron M; Yan R; Beach T; Sue L; Sabbagh M; Cai H; Wong P; Price D; Shen Y
    Proc Natl Acad Sci U S A; 2004 Mar; 101(10):3632-7. PubMed ID: 14978286
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Transgenic BACE expression in mouse neurons accelerates amyloid plaque pathology.
    Mohajeri MH; Saini KD; Nitsch RM
    J Neural Transm (Vienna); 2004 Mar; 111(3):413-25. PubMed ID: 14991462
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Gender-dependent transthyretin modulation of brain amyloid-β levels: evidence from a mouse model of Alzheimer's disease.
    Oliveira SM; Ribeiro CA; Cardoso I; Saraiva MJ
    J Alzheimers Dis; 2011; 27(2):429-39. PubMed ID: 21841252
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Dispersible amyloid β-protein oligomers, protofibrils, and fibrils represent diffusible but not soluble aggregates: their role in neurodegeneration in amyloid precursor protein (APP) transgenic mice.
    Rijal Upadhaya A; Capetillo-Zarate E; Kosterin I; Abramowski D; Kumar S; Yamaguchi H; Walter J; Fändrich M; Staufenbiel M; Thal DR
    Neurobiol Aging; 2012 Nov; 33(11):2641-60. PubMed ID: 22305478
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Hypercholesterolemia accelerates intraneuronal accumulation of Aβ oligomers resulting in memory impairment in Alzheimer's disease model mice.
    Umeda T; Tomiyama T; Kitajima E; Idomoto T; Nomura S; Lambert MP; Klein WL; Mori H
    Life Sci; 2012 Dec; 91(23-24):1169-76. PubMed ID: 22273754
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Connective tissue growth factor (CTGF) expression in the brain is a downstream effector of insulin resistance- associated promotion of Alzheimer's disease beta-amyloid neuropathology.
    Zhao Z; Ho L; Wang J; Qin W; Festa ED; Mobbs C; Hof P; Rocher A; Masur S; Haroutunian V; Pasinetti GM
    FASEB J; 2005 Dec; 19(14):2081-2. PubMed ID: 16186174
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Dynamics of {beta}-amyloid reductions in brain, cerebrospinal fluid, and plasma of {beta}-amyloid precursor protein transgenic mice treated with a {gamma}-secretase inhibitor.
    Barten DM; Guss VL; Corsa JA; Loo A; Hansel SB; Zheng M; Munoz B; Srinivasan K; Wang B; Robertson BJ; Polson CT; Wang J; Roberts SB; Hendrick JP; Anderson JJ; Loy JK; Denton R; Verdoorn TA; Smith DW; Felsenstein KM
    J Pharmacol Exp Ther; 2005 Feb; 312(2):635-43. PubMed ID: 15452193
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Temporal memory deficits in Alzheimer's mouse models: rescue by genetic deletion of BACE1.
    Ohno M; Chang L; Tseng W; Oakley H; Citron M; Klein WL; Vassar R; Disterhoft JF
    Eur J Neurosci; 2006 Jan; 23(1):251-60. PubMed ID: 16420434
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Effects of the superoxide dismutase/catalase mimetic EUK-207 in a mouse model of Alzheimer's disease: protection against and interruption of progression of amyloid and tau pathology and cognitive decline.
    Clausen A; Xu X; Bi X; Baudry M
    J Alzheimers Dis; 2012; 30(1):183-208. PubMed ID: 22406441
    [TBL] [Abstract][Full Text] [Related]  

  • 14. RAGE regulates BACE1 and Abeta generation via NFAT1 activation in Alzheimer's disease animal model.
    Cho HJ; Son SM; Jin SM; Hong HS; Shin DH; Kim SJ; Huh K; Mook-Jung I
    FASEB J; 2009 Aug; 23(8):2639-49. PubMed ID: 19332646
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Caloric restriction attenuates beta-amyloid neuropathology in a mouse model of Alzheimer's disease.
    Wang J; Ho L; Qin W; Rocher AB; Seror I; Humala N; Maniar K; Dolios G; Wang R; Hof PR; Pasinetti GM
    FASEB J; 2005 Apr; 19(6):659-61. PubMed ID: 15650008
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Immunomodulation of AβPP processing alleviates amyloid-β-related pathology in Alzheimer's disease transgenic mice.
    Arbel-Ornath M; Becker M; Rabinovich-Toidman P; Gartner M; Solomon B
    J Alzheimers Dis; 2010; 22(2):469-82. PubMed ID: 20847413
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Neuroprotective mechanism conferred by 17beta-estradiol on the biochemical basis of Alzheimer's disease.
    Amtul Z; Wang L; Westaway D; Rozmahel RF
    Neuroscience; 2010 Aug; 169(2):781-6. PubMed ID: 20493928
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Tenascin-C deficiency ameliorates Alzheimer's disease-related pathology in mice.
    Xie K; Liu Y; Hao W; Walter S; Penke B; Hartmann T; Schachner M; Fassbender K
    Neurobiol Aging; 2013 Oct; 34(10):2389-98. PubMed ID: 23673309
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The Swedish APP mutation alters the effect of genetically reduced BACE1 expression on the APP processing.
    Rabe S; Reichwald J; Ammaturo D; de Strooper B; Saftig P; Neumann U; Staufenbiel M
    J Neurochem; 2011 Oct; 119(1):231-9. PubMed ID: 21812781
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Myeloid differentiation factor 88-deficient bone marrow cells improve Alzheimer's disease-related symptoms and pathology.
    Hao W; Liu Y; Liu S; Walter S; Grimm MO; Kiliaan AJ; Penke B; Hartmann T; Rübe CE; Menger MD; Fassbender K
    Brain; 2011 Jan; 134(Pt 1):278-92. PubMed ID: 21115468
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.